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The synthesis and application of 3-arylazo-4-phenylthieno[2,3-c]isothiazole and ethyl 3-arylazo-4-phenylthieno[2,3-c]isothiazole-5-carboxylate [PDF]
Journal of the Serbian Chemical Society, 2005 The paper describes the synthesis of 3-amino-4-phenylthieno[2,3-c]isothiazole and ethyl 3-amino-4-phenylthieno[2,3-c]isothiazole-5-carboxylate and their utilization to prepare a range of azo disperse dyes.
G. G. PAWAR +4 more
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Isothiazole Derivatives as Antiviral Agents
Antiviral Chemistry and Chemotherapy, 2007 We recently described the synthesis and antiviral activity of the compounds 5-phenyl-3-(4-cyano-5-phenylisothiazol-3-yl) disulphanyl-4-isothiazole-carbonitrile and S-(4-cyano-5-phenylisothiazol-3-yl)- O-ethyl thiocarbonate, which were found to be effective against both HIV-1 (IIIB) and HIV-2 (ROD).
Adriana Garozzo +2 more
exaly +5 more sources
Reaction of 4,5-Dichloro-1,2,3-dithiazolium Chloride with 2-(Phenylsulfonyl)acetonitrile
Molbank, 2022 The reaction of 4,5-dichloro-1,2,3-dithiazolium chloride with 2-(phenylsulfonyl)acetonitrile (1 equiv) in the presence of pyridine (2 equiv) gave S-(3-chloro-5-cyanoisothiazol-4-yl)benzenesulfonothioate and (Z)-2-(4-chloro-5H-1,2,3-dithiazol-5-ylidene)-2-
Konstantinos Plakas +3 more
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Methyl 3-Bromo-5-carbamoylisothiazole-4-carboxylate
Molbank, 2023 Reaction of methyl 3-bromo-5-cyanoisothiazole-4-carboxylate with conc. H2SO4 gave methyl 3-bromo-5-carbamoylisothiazole-4-carboxylate in 93% yield. The compound was fully characterized.
Andreas S. Kalogirou +1 more
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3-Chloro-4-(p-tolyl)isothiazole-5-carbonitrile
Molbank, 2023 A reaction of 3-chloroisothiazole-5-carbonitrile with 1-iodo-4-methylbenzene (2 equiv.) produced 3-chloro-4-(p-tolyl)isothiazole-5-carbonitrile in a 60% yield. The compound was fully characterized.
Andreas S. Kalogirou +1 more
doaj +1 more source
Molecules, 2022 A series of N-acyl derivatives of anabasine and cytisine were prepared, to discover novel, natural product-based medicinal agents. All synthesized compounds were tested for antimicrobial, antifungal, antiviral and analgesic activity.
Gulim K. Mukusheva +8 more
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Synthesis of 3-Bromo-4-phenylisothiazole-5-carboxylic Acid and 3-Bromoisothiazole-5-carboxylic Acid
Molbank, 2023 Reactions of 3-bromo-4-phenylisothiazole-5-carboxamide and 3-bromoisothiazole-5-carboxamide with NaNO2 (4 equiv.), in TFA, at ca. 0 °C gave the carboxylic acid products in 99% and 95% yields, respectively. The two compounds were fully characterized.
Andreas S. Kalogirou +1 more
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Quinine Esters with 1,2-Azole, Pyridine and Adamantane Fragments
Molecules, 2022 An efficient method of producing quinine derivatives via reaction of acylation with 4,5-dichloroisothiazole-3-, 5-arylisoxazole-3-, adamantane- and hydrochlorides of pyridine-3- and pyridine-4-carbonyl chlorides was developed.
Gulim K. Mukusheva +7 more
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Isothiazolinone Biocides: Chemistry, Biological, and Toxicity Profiles
Molecules, 2020 The importance of isothiazole and of compounds containing the isothiazole nucleus has been growing over the last few years. Isothiazolinones are used in cosmetic and as chemical additives for occupational and industrial usage due to their bacteriostatic ...
Vânia Silva +5 more
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Molecules, 2021 Aquatic contamination by heavy metals is a major concern for the serious negative consequences it has for plants, animals, and humans. Among the most toxic metals, Cd(II) stands out since selective and truly efficient methodologies for its removal are ...
Joana F. Leal +6 more
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