Results 31 to 40 of about 871 (158)

5,5′-Thiobis(3-bromoisothiazole-4-carbonitrile)

Molbank
The reaction of sodium 2,2-dicyanoethene-1,1-bis(thiolate) with bromine (2 equiv.) in CCl4 gave 3,5-dibromoisothiazole-3-carbonitrile and 5,5′-thiobis(3-bromoisothiazole-4-carbonitrile) in 7% and 18% yields, respectively.
Andreas S. Kalogirou, Panayiotis A. Koutentis   +1 more
doaj   +1 more source

Photochemische Permutation von Indazolen zu Benzimidazolen

Angewandte Chemie, Volume 137, Issue 29, July 14, 2025.
Hier stellen wir eine photochemische Strategie für die direkte Permutation von 1H‐ und 2H‐Indazolen zu Benzimidazolen vor. Dieser Ansatz beruht auf einem zweistufigen Mechanismus aus Tautomerisierung im angeregten Zustand und photochemischer Umlagerung, bietet einen breiten Anwendungsbereich, hohe Ausbeuten und funktionelle Gruppentoleranz und erhöht ...
Thiago dos Santos, Cornelia S. Buettner, Dilara Berna Yildiz, Martina Mamone, Alessandro Ruffoni, Daniele Leonori   +5 more
wiley   +1 more source

Rational Design of Low-Band Gap Star-Shaped Molecules With 2,4,6-Triphenyl-1,3,5-triazine as Core and Diketopyrrolopyrrole Derivatives as Arms for Organic Solar Cells Applications

Frontiers in Chemistry, 2019
A series of D–A novel star-shaped molecules with 2,4,6-triphenyl-1,3,5-triazine (TPTA) as core, diketopyrrolo[3,4-c]pyrrole (DPP) derivatives as arms, and triphenylamine (TPA) derivatives as end groups have been systematically investigated for organic ...
Xinhao Zhang, Xinhao Zhang, Ruifa Jin, Ruifa Jin   +3 more
doaj   +1 more source

Photochemical Conversion of Indazoles into Benzimidazoles

Angewandte Chemie International Edition, Volume 64, Issue 29, July 14, 2025.
We present a photochemical strategy for transforming 1H‐ and 2H‐indazoles into benzimidazoles, enabling heteroaromatic interconversion under mild conditions. This approach, grounded in a two‐step mechanism of excited‐state tautomerization and photochemical rearrangement, offers broad scope, high yields, and functional group tolerance, expanding the ...
Thiago dos Santos, Cornelia S. Buettner, Dilara Berna Yildiz, Martina Mamone, Alessandro Ruffoni, Daniele Leonori   +5 more
wiley   +1 more source

Characterisation of a Tip60 specific inhibitor, NU9056, in prostate cancer.

PLoS ONE, 2012
Tip60 (KAT5) is a histone acetyltransferase (HAT enzyme) involved in multiple cellular processes including transcriptional regulation, DNA damage repair and cell signalling.
Kelly Coffey, Timothy J Blackburn, Susan Cook, Bernard T Golding, Roger J Griffin, Ian R Hardcastle, Lorraine Hewitt, Kety Huberman, Hesta V McNeill, David R Newell, Celine Roche, Claudia A Ryan-Munden, Anna Watson, Craig N Robson   +13 more
doaj   +1 more source

Synthesis and biological profile of substituted hexahydrofuro[3,4‐b]furans, a novel class of bicyclic acyl‐acyl carrier protein (ACP) thioesterase inhibitors

Pest Management Science, Volume 81, Issue 5, Page 2635-2651, May 2025.
The present work covers a series of novel herbicidal lead structures that possess a hexahydrofuro[3,4‐b]furan scaffold as a structural key feature, carrying ortho‐substituted aryloxy side chains. Based on an optimized synthetic approach a broader structure–activity relationship (SAR) study was carried out delivering some lead structures that show good ...
Hartmut Ahrens, David M. Barber, Guido Bojack, Birgit Bollenbach‐Wahl, Luke Churchman, Rahel Getachew, Hendrik Helmke, Sabine Hohmann, Bernd Laber, Gudrun Lange, Shaun Rees, Anna M. Reingruber, Dirk Schmutzler, Jens Frackenpohl   +13 more
wiley   +1 more source

Analysis of Volatile Components From Different Commercially Available Fenugreek Tinctures Based on GC‐IMS and SPME‐GC–MS and Their Correlation With Sensory Aroma

Food Science &Nutrition, Volume 13, Issue 4, April 2025.
This study examines the variations in the key volatile flavor compounds of several fenugreek tincture samples from various sources and their relationship with flavor characterization using GC‐IMS, SPME‐GC–MS, OAV, and DSA. This study elaborates on the intrinsic association between key flavor components and sensory flavor, as well as the contributions ...
Hua Zhang, Haifeng Shen, Yuanqing Ye, Fan Cao, Jiale Ren, Huaiyuan Zhu, Bo Chi, Huiyun Liao, Feng Li   +8 more
wiley   +1 more source

Synthesis of Novel Vanillin Derivatives Containing Isothiazole Moieties and its Synergistic Effect in Mixtures with Insecticides

Natural Product Communications, 2009
Reaction between 4-formyl-2-methoxyphenyl 4,5-dichloroisothiazole-3-carboxylate with various aromatic amines led to azomethins 2-7 formation. By treatment of azomethins 2-7 with sodium triacetoxyborohydride corresponding amines 8-11 were obtained. During
Vladimir Potkin, Yuri Zubenko, Anatoly Bykhovetz, Romualda Zolotar, Violetta Goncharuk   +4 more
doaj   +1 more source

Conventional and innovative approaches to black fungi control for stone heritage preservation

IUBMB Life, Volume 77, Issue 3, March 2025.
Abstract Black Meristematic Fungi (BMF) are characterized by a thick melanized cell wall and an isodiametric cellular expansion. BMF represent one of the most damaging groups of microorganisms causing the deterioration of outdoor exposed stone monuments mainly due to the formation of dark spots and patches leading to the darkening of their surface ...
Domenico Celi, Massimiliano Marvasi, Brunella Perito   +2 more
wiley   +1 more source

Discovery of Hydrazine Clubbed Thiazoles as Potential Antidiabetic Agents: Synthesis, Biological Evaluation, and Molecular Docking Studies

Drug Development Research, Volume 86, Issue 1, February 2025.
ABSTRACT In this study, hydrazine clubbed thiazole derivatives (3a–3j) were obtained by Hantzsch thiazole synthesis and characterized by MS, 1H NMR, and 13C NMR. The inhibitory potentials of the derivatives against diabetes‐related enzymes such as aldose reductase (AR), α‐glycosidase (α‐GLY), and α‐amylase (α‐AMY) were experimentally determined, and ...
Betül Kaya, Hakan Tahtacı, Bilge Çiftçi, Hatice Esra Duran, Adem Necip, Mesut Işık, Şükrü Beydemir   +6 more
wiley   +1 more source