Results 11 to 20 of about 871 (158)
Methyl 3-Bromo-5-carbamoylisothiazole-4-carboxylate
Molbank, 2023 Reaction of methyl 3-bromo-5-cyanoisothiazole-4-carboxylate with conc. H2SO4 gave methyl 3-bromo-5-carbamoylisothiazole-4-carboxylate in 93% yield. The compound was fully characterized.
Andreas S. Kalogirou +1 more
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3-Chloro-4-(p-tolyl)isothiazole-5-carbonitrile
Molbank, 2023 A reaction of 3-chloroisothiazole-5-carbonitrile with 1-iodo-4-methylbenzene (2 equiv.) produced 3-chloro-4-(p-tolyl)isothiazole-5-carbonitrile in a 60% yield. The compound was fully characterized.
Andreas S. Kalogirou +1 more
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Molecules, 2022 A series of N-acyl derivatives of anabasine and cytisine were prepared, to discover novel, natural product-based medicinal agents. All synthesized compounds were tested for antimicrobial, antifungal, antiviral and analgesic activity.
Gulim K. Mukusheva +8 more
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Synthesis of 3-Bromo-4-phenylisothiazole-5-carboxylic Acid and 3-Bromoisothiazole-5-carboxylic Acid
Molbank, 2023 Reactions of 3-bromo-4-phenylisothiazole-5-carboxamide and 3-bromoisothiazole-5-carboxamide with NaNO2 (4 equiv.), in TFA, at ca. 0 °C gave the carboxylic acid products in 99% and 95% yields, respectively. The two compounds were fully characterized.
Andreas S. Kalogirou +1 more
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Isothiazolinone Biocides: Chemistry, Biological, and Toxicity Profiles
Molecules, 2020 The importance of isothiazole and of compounds containing the isothiazole nucleus has been growing over the last few years. Isothiazolinones are used in cosmetic and as chemical additives for occupational and industrial usage due to their bacteriostatic ...
Vânia Silva +5 more
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Quinine Esters with 1,2-Azole, Pyridine and Adamantane Fragments
Molecules, 2022 An efficient method of producing quinine derivatives via reaction of acylation with 4,5-dichloroisothiazole-3-, 5-arylisoxazole-3-, adamantane- and hydrochlorides of pyridine-3- and pyridine-4-carbonyl chlorides was developed.
Gulim K. Mukusheva +7 more
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Zeitschrift für Kristallographie - New Crystal Structures, 2023 C11H6Cl2N2O3S2, triclinic, P1‾ (no. 2), a = 6.974(3) Å, b = 8.132(3) Å, c = 12.349(5) Å, α = 86.123(4)°, β = 78.299(4)°, γ = 85.715(4)°, V = 682.9(4) Å3, Z = 2, R gt(F) = 0.0410, wR ref(F 2) = 0.1058, T = 296(2) K.
Cong Huang +4 more
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2-(3-Methylbut-2-en-1-yl)-1,2-benzisothiazol-3(2H)-one 1,1-dioxide
Acta Crystallographica Section E, 2009 In the title compound, C12H13NO3S, a saccharin derivative, the dihedral angle between the aromatic and isothiazole rings is 2.91 (12)°. The planar 3,3-dimethylallyl group [maximum deviation = 0.0086 (16) Å]
Hafiz Mubashar-ur-Rehman +4 more
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Molecules, 2019 Thanks to the progress in oncology, pharmacological treatment of cancer is gaining in importance and in the near future anti-cancer chemotherapeutics are expected to be the main method of treatment for cancer diseases.
Izabela Jęśkowiak +6 more
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Natural Product Communications, 2018 Methyl 5-hydroxy-4-oxo-4 H -pyran-2-carboxylate was synthesized by esterification of methanol with comenic acid under acidic catalysis. The obtained ester was alkylated with 3-(chloromethyl)-5-phenylisoxazole and 4,5-dichloro-3-(chloromethyl)isothiazole ...
Alexey V. Kletskov +9 more
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