Results 21 to 30 of about 1,392 (198)

2-(3-Methylbut-2-en-1-yl)-1,2-benzisothiazol-3(2H)-one 1,1-dioxide

Acta Crystallographica Section E, 2009
In the title compound, C12H13NO3S, a saccharin derivative, the dihedral angle between the aromatic and isothiazole rings is 2.91 (12)°. The planar 3,3-dimethylallyl group [maximum deviation = 0.0086 (16) Å]
Hafiz Mubashar-ur-Rehman, Muhammad Humayun Bilal, Islam Ullah Khan, M. Nawaz Tahir, Muhammad Nadeem Arshad   +4 more
doaj   +1 more source

Synthesis and Biological Activity of Novel Comenic Acid Derivatives Containing Isoxazole and Isothiazole Moieties

Natural Product Communications, 2018
Methyl 5-hydroxy-4-oxo-4 H -pyran-2-carboxylate was synthesized by esterification of methanol with comenic acid under acidic catalysis. The obtained ester was alkylated with 3-(chloromethyl)-5-phenylisoxazole and 4,5-dichloro-3-(chloromethyl)isothiazole ...
Alexey V. Kletskov, Vladimir I. Potkin, Irina A. Kolesnik, Sergey K. Petkevich, Anastasia V. Kvachonak, Margarita O. Dosina, Diana O. Loiko, Maria V. Larchenko, Svetlana G. Pashkevich, Vladimir A. Kulchitsky   +9 more
doaj   +1 more source

A novel synthesis of fused isothiazole ring systems [PDF]

, 1994
The reaction of aromatic and heteroaromatic aldehydes with bis(trimethylsilyl)sulfide leads to the corresponding thioaldehydes, which, through a fine tuning of the reaction conditions, are trapped both intermolecularly and intramolecularly, thus ...
Capperucci, Antonella, SPAGNOLO, Piero, A. CAPPERUCCI, DEGL'INNOCENTI, Alessandro, FUNICELLO, Maria, SCAFATO, Patrizia   +5 more
core   +1 more source

The N’-Substituted Derivatives of 5-Chloro-3-Methylisothiazole-4-Carboxylic Acid Hydrazide with Antiproliferative Activity

Molecules, 2019
Thanks to the progress in oncology, pharmacological treatment of cancer is gaining in importance and in the near future anti-cancer chemotherapeutics are expected to be the main method of treatment for cancer diseases.
Izabela Jęśkowiak, Stanisław Ryng, Marta Świtalska, Joanna Wietrzyk, Iwona Bryndal, Tadeusz Lis, Marcin Mączyński   +6 more
doaj   +1 more source

A Mixture of D-Amino Acids Enhances the Biocidal Efficacy of CMIT/MIT Against Corrosive Vibrio harveyi Biofilm

Frontiers in Microbiology, 2020
Biocides are widely used for the mitigation of microbial contamination, especially in the field of the aviation fuel industry. However, the long-term use of biocide has raised the concerns regarding the environmental contamination and microbial drug ...
Xiaomeng Liu, Xiaomeng Liu, Xiaomeng Liu, Zhong Li, Zhong Li, Yongqiang Fan, Yongqiang Fan, Yassir Lekbach, Yassir Lekbach, Yongbo Song, Dake Xu, Dake Xu, Zhichao Zhang, Lei Ding, Fuhui Wang, Fuhui Wang   +15 more
doaj   +1 more source

Synthesis, Fungicidal Activity and Plant Protective Properties of 1,2,3-Thiadiazole and Isothiazole-Based N-acyl-N-arylalaninates

Molecules, 2023
The addition of active groups of known fungicides, or systemic acquired resistance inducers, into novel compound molecules to search for potential antifungal compounds is a popular and effective strategy.
Tatiana A. Kalinina, Valeriya I. Balandina, Konstantin L. Obydennov, Pavel A. Slepukhin, Zhijin Fan, Vasiliy A. Bakulev, Tatiana V. Glukhareva   +6 more
doaj   +1 more source

Chemistry of polyhalogenated nitrobutadienes, 10: Synthesis of highly functionalized heterocycles with a rigid 6-amino-3-azabicyclo[3.1.0]hexane moiety

Beilstein Journal of Organic Chemistry, 2012
The nitropolychlorobutadienes 3, 4 are valuable building blocks for various amination and successive heterocyclization products. Nucleophilic substitution reactions of the partially protected, bioactive amines 1, 2 with either vinyl, imidoyl or carbonyl ...
Viktor A. Zapol’skii, Jan C. Namyslo, Armin de Meijere, Dieter E. Kaufmann   +3 more
doaj   +1 more source

Thienoisothiazoles. I. The synthesis of Thieno[2,3-c]isothiazole and some of its derivatives

, 1982
.Thieno[2,3-c]isothiazole-3-carboxylic acid was the compound obtained by the reaction of ethyl-3-cyano-5,5-diethoxy-2-oxopentanoate with phosphorus pentasulfide, previously assumed to yield thieno[3,4-d]isothiazole-4-carboxylic acid. The parent thieno[2,
HD Krebs, FC James
core   +1 more source

Isothiazoles. Part V. Cycloaddition reaction of nitrile oxides to 3-diethylamino-4-(4-methoxyphenyl)-isothiazole 1,1-dioxide: An entry to 5-acyl- and 5-cyano-isothiazole 1,1-dioxide derivatives

, 1995
Nitrile oxides 2 reacted with 3-diethylamino-4-(4-methoxyphenyl)-isothiazole 1,1-dioxide (1) affording through a highly regioselective 1,3-dipolar cycloaddition reaction isothiazolo[5,4-d]isoxazoline 4,4-dioxides 3.
M.L. Gelmi, F. Clerici, F. Ferraris, Maria L. Gelmi, Federica Ferraris, Franceses Clerici   +5 more
core   +1 more source

Isothiazolo[5,4-d]isoxazole S,S-dioxides and pyrazolo [3,4-d]-isothiazole S,S-dioxides through cycloaddition reaction on 3-benzylaminoisothiazole S,S-dioxides

, 2006
By reacting 4,5-unsubstituted isothiazole dioxides with diazoalkanes and nitrile oxides bicyclic pyrazolo[3,4-d]isothiazole and isothiazolo[5,4-d]isoxazole S,S-dioxides were obtained in good yield through a regioselective cycloaddn. reaction.
M.L. Gelmi, C. Monzani, A. Sala, F. Clerici, D. Pocar   +4 more
core   +1 more source