Results 201 to 210 of about 31,405 (257)

A machine learning-derived polygenic risk score reveals that healthy lifestyle counteracts obesity-related mortality. [PDF]

NPJ Digit Med
Xiao L, Liang S, Zeng L, Cai S, Wang J, Hong C, Li Y, Li R, Jiang P, Xie Z, Li T, Wu S, Liu L, Wu G, Lai W.   +14 more
europepmc   +1 more source

Decoding stress resilience in soybean: Regulatory networks and precision breeding under climate change

Journal of Integrative Plant Biology, EarlyView.
This review covers recent progress in the understanding of stress‐responsive regulatory networks in soybean and highlights emerging genomic and breeding strategies. Integrating molecular insights and precision breeding will help to accelerate the development of climate‐resilient soybean cultivars.
Ali Shahzad, Monan Sun, Shuangkang Pei, Xiaoyu Liu, Yinhe Zhang, Keheng Xu, Hongtao Gao, Yonggang Zhou, Haiyan Li   +8 more
wiley   +1 more source

Reconfiguring biofortification strategies to transform food systems and address micronutrient deficiency of the 21st century

Journal of Integrative Plant Biology, EarlyView.
This review explores how to make staple foods and horticultural crops more nutritious, including how artificial intelligence‐based screening of gene banks helps deploy nutritionally rich germplasm into breeding. Genome editing can help develop crops richer in minerals, vitamins, and health‐promoting compounds, supporting healthier diets and more ...
Rhowell Jr. N. Tiozon, Alisdair R. Fernie, Nese Sreenivasulu   +2 more
wiley   +1 more source

MPGK: A user-friendly tool for Mendelian randomization, polygenic risk score, Geno Ontology, and the Kyoto Encyclopedia of Genes and Genomes analysis. [PDF]

Chin Med J (Engl)
Yang J, Song X, Xu J, Yang Y, Zuo X, Cui Y.   +5 more
europepmc   +1 more source

Genomic Medicine Sweden: Advancing precision medicine at the national level

Journal of Internal Medicine, EarlyView.
Abstract High‐throughput sequencing has transformed clinical diagnostics of rare diseases (RD), cancer and infectious diseases by enabling the identification of disease‐causing genetic alterations and facilitating individualised treatment and care.
Anders Edsjö, Anna Lindstrand, Panagiotis Baliakas, David Gisselsson, Paula Mölling, Mia Wadelius, Åsa Johansson, Hannes Olauson, Hans Ehrencrona, Lovisa Lovmar, Christian G. Giske, Henrik Green, Ann Nordgren, Fulya Taylan, Martin Hallbeck, Erika Tång Hallbäck, Anna Green, Markus Heidenblad, Kina Höglund, Anders Jemt, Carl Mårten Lindqvist, Maria Johansson Soller, Magnus Sabel, Colum Walsh, Hartmut Vogt, Craig E. Wheelock, Martin Bergö, Jens Enoksson, Ann Ekberg Jansson, Cecilia Fagerström, Jan Holgersson, Stephanie Anja Juran, Mats G. Karlsson, Frida Lundmark, Eva Tiensuu Janson, Andreas Muranyi Scheutz, Malin Sund, Päivi Östling, Sofia Gruvberger‐Saal, Marene Landström, Malin Melin, Lars Palmqvist, Richard Palmqvist, Bianca Stenmark, Anna Wedell, Malin Karnå, Katarina Nyström, Tobias Strid, Per Sikora, Maria Johansson, Therese Fagerqvist, Mirja Carlsson Möller, Oskar Frisell, Mats Ulfendahl, Mikaela Friedman, Lucia Cavelier, Valtteri Wirta, Thoas Fioretos, Richard Rosenquist   +58 more
wiley   +1 more source

Do Genetics Shape Mental Health Trajectories Around Partnership Transitions?

Journal of Marriage and Family, EarlyView.
ABSTRACT Objective This study focuses on the extent to which genetic risk for mental disorders contributes to observed mental health problems before and after partnership transitions. Background Partnership formation and dissolution are linked to short‐term changes in mental health, with outcomes varying by gender, socioeconomic position, and other ...
Philipp Dierker, Maria Gueltzow, Hannu Lahtinen, Mine Kühn, Pekka Martikainen, Mikko Myrskylä   +5 more
wiley   +1 more source

Does Combining the STarT Back Tool With a Polygenic Risk Score for Chronic Low Back Pain Improve Prediction of Work Disability Over 2 Years? [PDF]

Eur J Pain
Compte R, Naeini MK, Heikkala E, McSweeney T, Karppinen J, Williams FMK.   +5 more
europepmc   +1 more source