Results 211 to 220 of about 7,071,839 (288)

Addition of CAD polygenic risk score to coronary artery calcium score enhances prediction of MACE. [PDF]

Front Cardiovasc Med
Maryniak A, Oleszak F, Coy K, Larson E, Hajek C, Bartaria S, Gu S, Weaver M, Rotter JI, Guo X, Tan J, Lin HJ, Stys A, Baran N, Stys T.   +14 more
europepmc   +1 more source

The Effect of PTPN22 Polymorphism on Juvenile Idiopathic Arthritis Subtypes and Disease Activity in a Finnish Study Population

International Journal of Immunogenetics, EarlyView.
ABSTRACT Genetic factors that modulate immune regulation are increasingly recognised as contributors to the heterogeneity and clinical course of autoimmune diseases. Polymorphisms of protein tyrosine phosphatase non‐receptor type 22 (PTPN22) are associated with several autoimmune diseases.
Sonja Kvist, Johanna Teräsjärvi, Heidi Rahikkala, Jussi Mertsola, Milja Möttönen, Qiushui He   +5 more
wiley   +1 more source

Heritability of Productive, Reproductive and Carcass Traits in Pure‐Bred and Cross‐Bred Pigs: A Systematic Review and Meta‐Analysis

Journal of Animal Breeding and Genetics, EarlyView.
ABSTRACT Heritability (h2) is a key parameter in animal breeding, but its magnitude and consistency across pure‐bred (PB) and cross‐bred (CB) pig populations remain poorly understood. This study aimed to compare heritability estimates between PB and CB populations for economically relevant traits through a systematic review and meta‐analysis.
Wilber Hernández‐Montiel, Amada I. Osorio‐Terán, Víctor M. Meza‐Villalvazo, Adolfo Amador‐Mendoza, José Abad‐Zavaleta, Nicolás Valenzuela‐Jiménez, Mario Alberto Martínez‐Núñez   +6 more
wiley   +1 more source

Genome‐Wide Association Studies for Anogenital Distance and Linear Type Traits in Gir Cattle

Journal of Animal Breeding and Genetics, EarlyView.
ABSTRACT Although linear type traits have been under selection in the Dairy Gir cattle for the past three decades, there are few studies exploring genetic architecture for these traits. The aim of this study was to identify candidate genes for anogenital distance and linear type traits in the Gir breed. For this study, the body measures of rump length (
Renata de Fátima Bretanha Rocha, Andréia Ferreira Machado, Fabrício Pilonetto, Marcos Vinícius Barbosa da Silva, Domingos Lollobrigida de Souza Netto, José Domingos Guimarães, Fábio Luiz Buranelo Toral, Victor E. Gomez Leon, Simone Eliza Facioni Guimarães   +8 more
wiley   +1 more source

Polygenic Risk Modelling in Periodontitis: Insights From a Feasibility Study of 4243 European Cases and Current Limitations

Journal of Clinical Periodontology, EarlyView.
ABSTRACT Background and Aim Genetic susceptibility plays a particularly important role in early‐onset (EO) and severe periodontitis (PD). The genetic risk remains largely unexplained because of limited sample sizes and heterogeneous phenotypes in genome‐wide association studies (GWAS).
Gesa M. Richter, O. Mercy Akinloye, M. Kamal Nasr, Birte Holtfreter, Alicia de Coo, Silvia Diz De Almeida, Bruno G. Loos, Søren Jepsen, Henrik Dommisch, Corinna Bruckmann, Ines Kapferer‐Seebacher, PerioGEN Cohort Group, Georg Homuth, Thomas Kocher, Henry Völzke, Klaus Berger, Matthias Laudes, Wolfgang Lieb, Nathalie van der Velde, Natasja van Schoor, Lisette de Groot, Juan Blanco, Angel Carracedo, Raquel Cruz, Astrid Dempfle, Alexander Teumer, Arne S. Schaefer, Sandra Freitag‐Wolf   +27 more
wiley   +1 more source

Predictive value of the Alzheimer polygenic risk score on cognitive decline in patients with mild cognitive impairment and Alzheimer's disease dementia. [PDF]

J Prev Alzheimers Dis
Calm B, Hinojosa-Calleja A, García-Gutiérrez F, Blazquez-Folch J, Alegret M, Fernández MV, De Rojas I, García-González P, Olivé C, Valenzuela-Seba A, Bayón-Buján P, Cano A, Puerta R, Capdevila-Bayo M, Muñoz-Morales Á, Miguel A, Solivar A, Montrreal L, Sanz-Cartagena P, Rosende-Roca M, Cantero-Fortiz Y, Gurruchaga MJ, Tárraga L, Boada M, Marquié M, Ruiz A, Valero S, Alzheimer’s Disease Neuroimaging Initiative.   +27 more
europepmc   +1 more source

Annual Research Review: Associations of socioeconomic status with cognitive function, language ability, and academic achievement in youth: a systematic review of mechanisms and protective factors

Journal of Child Psychology and Psychiatry, Volume 66, Issue 4, Page 417-439, April 2025.
Low socioeconomic status (SES) is negatively associated with children's cognitive and academic performance, leading to long‐term educational and economic disparities. In particular, SES is a powerful predictor of executive function (EF), language ability, and academic achievement.
Divyangana Rakesh, Paris Anne Lee, Amruta Gaikwad, Katie A. McLaughlin   +3 more
wiley   +1 more source

Polygenic risk score with KLK3 SNP-SNP interaction pairs for predicting prostate cancer aggressiveness. [PDF]

Commun Med (Lond)
Lin HY, Sarkar I, Mazumder H, Huang PY, Muir KR, Schleutker J, Pashayan N, Batra J, Neal DE, Grönberg H, Nielsen SF, Nordestgaard BG, Tangen CM, MacInnis RJ, Wolk A, Albanes D, Travis RC, Stanford JL, Mucci LA, Kibel AS, Cussenot O, Berndt SI, Koutros S, Sørensen KD, Cybulski C, Grindedal EM, Hoegel J, Maier C, Hamilton RJ, Rosenstein BS, Vega A, Kogevinas M, Wiklund F, Penney KL, Teixeira MR, Brenner H, John EM, Kaneva R, Logothetis CJ, Neuhausen SL, De Ruyck K, Ost P, Gamulin M, Usmani N, Claessens F, Castelao JE, Townsend PA, UKGPCS collaborators, APCB BioResource (Australian Prostate Cancer BioResource), Kote-Jarai Z, Haiman CA, Eeles RA, PRACTICAL consortium, Park JY.   +53 more
europepmc   +1 more source

Co‐development of ADHD symptoms and emotional problems from childhood to adulthood: predictors and developmental outcomes

Journal of Child Psychology and Psychiatry, EarlyView.
Background Attention‐deficit/hyperactivity disorder (ADHD) symptoms and emotional problems frequently co‐occur. Longitudinal data provide opportunities to understand how and why they co‐develop. Methods Data were drawn from the Twins Early Development Study, which included 27,890 participants.
Yuan You, Helena M.S. Zavos, Laurie J. Hannigan, Linlin Zhang, Giacomo Bignardi, Meredith X. Han, Elisavet Palaiologou, Christopher Rayner, Tom A. McAdams   +8 more
wiley   +1 more source

A polygenic risk score modifies the cardiovascular risk associated with obstructive sleep apnea. [PDF]

Sleep Adv
Thorball CW, Waeber A, Solelhac G, Hodel F, Imler T, Heiniger G, de La Harpe R, Marques-Vidal P, Vollenweider P, Fellay J, Heinzer R.   +10 more
europepmc   +1 more source