Results 141 to 150 of about 2,929,620 (353)
JAMA psychiatry, 2017 Importance Lithium is a first-line mood stabilizer for the treatment of bipolar affective disorder (BPAD). However, the efficacy of lithium varies widely, with a nonresponse rate of up to 30%. Biological response markers are lacking.
Azmeraw T. Amare +111 more
semanticscholar +1 more source
Spatiotemporal distribution of neural crest cells in the common wall lizard Podarcis muralis
Developmental Dynamics, EarlyView.Abstract Background Neural crest cells (NCCs) are migratory embryonic stem cells that give rise to a diverse set of cell types. Here we describe the dynamic distribution of NCCs in developing embryos of the common wall lizard Podarcis muralis inferred from 10 markers.
Robin Pranter, Nathalie Feiner
wiley +1 more source
The Plant Genome, Volume 15, Issue 4, December 2022., 2022 Abstract The growing demand for food and feed crops in the world because of growing population and more extreme weather events requires high‐yielding and resilient crops. Many agriculturally important traits are polygenic, controlled by multiple regulatory layers, and with a strong interaction with the environment.
Marta Malinowska +12 more
wiley +1 more source
Analysis of genetic differences between psychiatric disorders: Exploring pathways and cell-types/tissues involved and ability to differentiate the disorders by polygenic scores [PDF]
arXiv, 2020 Although displaying genetic correlations, psychiatric disorders are clinically defined as categorical entities as they each have distinguishing clinical features and may involve different treatments. Identifying differential genetic variations between these disorders may reveal how the disorders differ biologically and help to guide more personalized ...
arxiv
American Journal of Psychiatry, 2019 OBJECTIVE Different cognitive development histories in schizophrenia may reflect variation across dimensions of genetic influence. The authors derived and characterized cognitive development trajectory subgroups within a schizophrenia sample and profiled
D. Dickinson +5 more
semanticscholar +1 more source
ESC Heart Failure, EarlyView.Abstract Aims Patients with cardiomyopathies are a heterogeneous group of patients who experience high morbidity and mortality. Early cardiac assessment and intervention with access to genetic counselling in a multidisciplinary Cardiomyopathy Clinic may improve outcomes and prevent progression to advanced heart failure.
Chandu Sadasivan +12 more
wiley +1 more source
The Plant Genome, Volume 15, Issue 4, December 2022., 2022 Abstract The success of genomic selection (GS) in breeding schemes relies on its ability to provide accurate predictions of unobserved lines at early stages. Multigeneration data provides opportunities to increase the training data size and thus, the likelihood of extracting useful information from ancestors to improve prediction accuracy.
Marco Lopez‐Cruz +12 more
wiley +1 more source
Environmental and Molecular Mutagenesis, EarlyView.Abstract Exposure levels without appreciable human health risk may be determined by dividing a point of departure on a dose–response curve (e.g., benchmark dose) by a composite adjustment factor (AF). An “effect severity” AF (ESAF) is employed in some regulatory contexts.
Barbara L. Parsons +17 more
wiley +1 more source
Alfalfa genomic selection for different stress‐prone growing regions
The Plant Genome, Volume 15, Issue 4, December 2022., 2022 Abstract Alfalfa (Medicago sativa L.) selection for stress‐prone regions has high priority for sustainable crop–livestock systems. This study assessed the genomic selection (GS) ability to predict alfalfa breeding values for drought‐prone agricultural sites of Algeria, Morocco, and Argentina; managed‐stress (MS) environments of Italy featuring moderate
Paolo Annicchiarico +9 more
wiley +1 more source