Results 211 to 220 of about 3,197,012 (359)
Movement Disorders, EarlyView.Abstract Background Recent advances in proteomic profiling have enabled its use as a powerful approach in elucidating molecular mechanisms underlying Parkinson's disease, enabling the identification of disease‐associated protein alterations and candidate biomarkers for diagnosis, progression, and therapeutic response.
Victoria J. Dardov +21 more
wiley +1 more source
Movement Disorders, EarlyView.Abstract The association between alcohol consumption and Parkinson's disease (PD) risk remains unclear, whereas smoking has an inverse relationship with the disease. This study systematically reviewed and meta‐analyzed 16 studies (2014–2024) from PubMed, Scopus, Web of Science, MEDLINE, and the Cochrane Library to assess the relationship between ...
Sahar Hemeda +8 more
wiley +1 more source
Diagnosis and Management of Prenatal Hereditary Pyropoikilocytosis
Prenatal Diagnosis, EarlyView.ABSTRACT Hereditary pyropoikilocytosis (HPP) is a severe hemolytic anemia caused by variants in SPTA1, SPTB, and EPB41. These weaken horizontal interactions in the erythrocyte cytoskeleton, causing membrane fragmentation and splenic sequestration. It will readily cause fetal anemia and often hydrops fetalis. Prenatal diagnosis requires first ruling out
Connor Hartzell +6 more
wiley +1 more source
Polygenic risk scores: An overview from bench to bedside for personalised medicine [PDF]
, 2022 Benjamin Cross +2 more
openalex +1 more source
PLANTS, PEOPLE, PLANET, EarlyView.Agricultural production systems in the global North combine monocultures of specialised varieties and breeds with external interventions and inputs. Increasing the diversity of varieties, breeds and species may increase the system's resilience to external pressures through beneficial interactions.
Marinus J. M. Smulders +13 more
wiley +1 more source
Cell-type-specific Alzheimer’s disease polygenic risk scores are associated with distinct disease processes in Alzheimer’s disease [PDF]
, 2023 Hyun‐Sik Yang +16 more
openalex +1 more source
PLANTS, PEOPLE, PLANET, EarlyView.Biodiversity is threatened by human activities, with extinction debt accumulating rapidly. Many of these activities change the connectivity of populations, fragmenting existing population systems or bringing previously isolated populations or species into contact.
Zhiqin Long +7 more
wiley +1 more source
Estimating the impact of transmitted and non-transmitted psychiatric and neurodevelopmental polygenic scores on youth emotional problems [PDF]
, 2023 Amy Shakeshaft +6 more
openalex +1 more source
PLANTS, PEOPLE, PLANET, EarlyView.Climate extremes threaten the sustainability of cranberry production, a culturally and economically important North American crop. This study demonstrates that wild cranberries (Vaccinium oxycoccos) harbor genetic variation that may enhance cold stress resilience when introduced into cultivated cranberry through hybridization.
Audrey Dickinson +5 more
wiley +1 more source
F31. POLYGENIC RISK SCORES AND EARLY RISK ENDOPHENOTYPES IN CHILDREN AT GENETIC RISK OF SCHIZOPHRENIA AND BIPOLAR DISORDER: IMPLICATIONS FOR THE DEFINITION OF THE CHILDHOOD RISK STATUS [PDF]
, 2018 Thomas Paccalet +8 more
openalex +1 more source