Results 211 to 220 of about 2,929,620 (353)

Validation of a Genome-Wide Polygenic Score for Coronary Artery Disease in South Asians.

Journal of the American College of Cardiology, 2020
Minxian Wang, R. Menon, Sanghamitra Mishra, A. Patel, M. Chaffin, Deepak Tanneeru, Manjari Deshmukh, Oshin Mathew, Sanika Apte, Christina S Devanboo, Sumathi Sundaram, P. Lakshmipathy, S. Murugan, K. Sharma, K. Rajendran, S. Santhosh, R. Thachathodiyl, Hisham Ahamed, Aniketh Vijay Balegadde, T. Alexander, K. Swaminathan, Rajeev Gupta, A. Mullasari, A. Sigamani, M. Kanchi, A. Peterson, A. Butterworth, J. Danesh, E. di Angelantonio, A. Naheed, M. Inouye, Rajiv Chowdhury, Ramprasad Vedam, S. Kathiresan, Ravi Gupta, A. Khera   +35 more
semanticscholar   +1 more source

Application of artificial intelligence in myopia prevention and control

Pediatric Investigation, EarlyView.
Current applications of artificial intelligence (AI) in the field of myopia prevention and control were comprehensively reviewed. Challenges, current development status, and future directions of AI have also been discussed, holding great significance for the further application of AI in myopia management.
Nan Liu, Li Li, Jifeng Yu
wiley   +1 more source

Genome-wide association study of suicide attempt in psychiatric disorders identifies association with major depression polygenic risk scores [PDF]

, 2018
Niamh Mullins, Tim B. Bigdeli, Anders D. Børglum, Jonathan R. I. Coleman, Ditte Demontis, Ayman H. Fanous, Divya Mehta, Robert A. Power, Stephan Ripke, Eli A. Stahl, Anna Starnawska, Adebayo Anjorin, Aiden Corvin, Alan R. Sanders, Andreas J. Forstner, Andreas Reif, Anna C. Koller, Beata Świątkowska, Bernhard T. Baune, Bertram Müller‐Myhsok, Bettina Konte, Brenda W.J.H. Penninx, Carlos N. Pato, Clement C. Zai, Dan Rujescu, Digby Quested, Douglas F. Levinson, Elisabeth B. Binder, Enda M. Byrne, Esben Agerbo, Fabian Streit, Fermín Mayoral, Frank Bellivier, Franziska Degenhardt, Gerome Breen, Gunnar Morken, Gustavo Turecki, Guy A. Rouleau, Hans J. Grabe, Henry Völzke, Ina Giegling, Ingrid Agartz, Ingrid Melle, Jacob Lawrence, James B. Potash, James Walters, Jana Strohmaier, Jianxin Shi, Joanna Hauser, Joanna M. Biernacka, John B. Vincent, John R. Kelsoe, John S. Strauss, Jolanta Lissowska, Jonathan Pimm, Jordan W. Smoller, José Guzmán‐Parra, Klaus Peter Berger, Laura J. Scott, Maria Helena Pinto de Azevedo, Maciej Trzaskowski, Manolis Kogevinas, Marcella Rietschel, Marco P. Boks, Marcus Ising, Maria Grigoroiu‐Serbânescu, Marian L. Hamshere, Marion Leboyer, Mark A. Frye, Markus M. Nöthen, Martin Alda, Martin Preisig, Merete Nordentoft, Michael Boehnke, Michael O’Donovan, Michael J. Owen, Michele T. Pato, Miguel E. Rentería, Monika Budde, Myrna M. Weissman, Naomi R. Wray, Nicholas Bass, Olav B. Smeland, Ole A. Andreassen, Ole Mors, Pablo V. Gejman, Pamela Sklar, Patrick J. McGrath, Per Hoffmann, Peter McGuffin, Phil H. Lee, René S. Kahn, Roel A. Ophoff, Rolf Adolfsson, Sandra Van der Auwera, Srdjan Djurovic, Stanley I. Shyn, Stefan Kloiber, Stefanie Heilmann‐Heimbach, Stéphane Jamain   +99 more
openalex   +1 more source

Urinary Proteomics and Systems Biology Link Eight Proteins to the Higher Risk of Hypertension and Related Complications in Blacks Versus Whites

PROTEOMICS, EarlyView.
ABSTRACT Blacks are more prone to salt‐sensitive hypertension than Whites. This cross‐sectional analysis of a multi‐ethnic cohort aimed to search for proteins potentially involved in the susceptibility to salt sensitivity, hypertension, and hypertension‐related complications.
De‐Wei An, Dries S. Martens, Gontse G. Mokwatsi, Yu‐Ling Yu, Babangida S. Chori, Agnieszka Latosinska, Godsent Isiguzo, Susanne Eder, Dong‐Yan Zhang, Gert Mayer, Ruan Kruger, Jana Brguljan‐Hitij, Christian Delles, Catharina M. C. Mels, Katarzyna Stolarz‐Skrzypek, Marek Rajzer, Peter Verhamme, Aletta E. Schutte, Tim S. Nawrot, Yan Li, Harald Mischak, Augustine N. Odili, Jan A. Staessen   +22 more
wiley   +1 more source

Genetic distance informs polygenic score predictive accuracy. [PDF]

Trends Genet, 2023
Wojcik GL.
europepmc   +1 more source

A comprehensive review of the genetic control of cooking time in dry beans (Phaseolus vulgaris L.)

PLANTS, PEOPLE, PLANET, EarlyView.
Reducing cooking time could increase dry beans (Phaseolus vulgaris) consumption. Cooking is an essential processing step needed to unlock the nutrients in dry beans and to make them palatable and safe for consumption. Long cooking times have consequences for dry bean use, especially where cooking fuel cost is high and when people prefer foods that are ...
Hannah R. Jeffery, Marcelo Efrén Murillo‐Quesada, Luis Barboza‐Barquero, Karen Cichy   +3 more
wiley   +1 more source

A biologically-informed polygenic score identifies endophenotypes and clinical conditions associated with the insulin receptor function on specific brain regionsResearch in context

EBioMedicine, 2019
Background: Activation of brain insulin receptors modulates reward sensitivity, inhibitory control and memory. Variations in the functioning of this mechanism likely associate with individual differences in the risk for related mental disorders ...
Shantala A. Hari Dass, Kathryn McCracken, Irina Pokhvisneva, Lawrence M. Chen, Elika Garg, Thao T.T. Nguyen, Zihan Wang, Barbara Barth, Moein Yaqubi, Lisa M. McEwen, Julie L. MacIsaac, Josie Diorio, Michael S. Kobor, Kieran J. O'Donnell, Michael J. Meaney, Patricia P. Silveira   +15 more
doaj  

Polygenic risk score increases schizophrenia liability through cognition-relevant pathways [PDF]

, 2018
Timothea Toulopoulou, Xiaowei Zhang, Stacey S. Cherny, Dwight Dickinson, Karen F. Berman, Richard E. Straub, Pak C. Sham, Daniel R. Weinberger   +7 more
openalex   +1 more source

Comparing Venous vs. Capillary Blood Collection Methods for Proteomic Measurement in Peripheral Blood

PROTEOMICS – Clinical Applications, EarlyView.
ABSTRACT Background Capillary blood collection has a number of advantages over venous collection, especially in the context of increasing decentralized clinical trials and field‐based testing. No studies are available comparing venous versus capillary blood collection for proteomics measurement.
Mary Ni Lochlainn, Nathan J. Cheetham, Mario Falchi, Paolo Piazza, Claire J. Steves   +4 more
wiley   +1 more source

Genetic heterogeneity in depressive symptoms following the death of a spouse: Polygenic score analysis of the US Health and Retirement Study

, 2016
Benjamin W. Domingue, Hexuan Liu, Aysu Okbay, Daniel W. Belsky   +3 more
openalex   +1 more source