Results 81 to 90 of about 21,037 (206)

Chaperones Hsp70 and Hsp40 Suppress Aggregate Formation and Apoptosis in Cultured Neuronal Cells Expressing Truncated Androgen Receptor Protein with Expanded Polyglutamine Tract [PDF]

, 2000
Yasushi Kobayashi, Akito Kume, Mei Li, Manabu Doyu, Mami Hata, Kenzo Ohtsuka, Gen Sobue   +6 more
openalex   +1 more source

Inhibition of mTOR induces autophagy and reduces toxicity of polyglutamine expansions in fly and mouse models of Huntington disease

Nature Genetics, 2004
B. Ravikumar, C. Vacher, Z. Berger, J. Davies, S. Luo, L. Oroz, F. Scaravilli, D. Easton, R. Duden, C. O’Kane, D. Rubinsztein   +10 more
semanticscholar   +1 more source

The Polyglutamine Expansion in Spinocerebellar Ataxia Type 6 Causes a β Subunit-Specific Enhanced Activation of P/Q-Type Calcium Channels in Xenopus Oocytes [PDF]

, 2000
Sophie Restituito, Randall M. Thompson, Jacob Eliet, Robert S. Raike, Maureen S. Riedl, Pierre Charnet, Christopher M. Gómez   +6 more
openalex   +1 more source

Longer polyglutamine tracts in the androgen receptor are associated with moderate to severe undermasculinized genitalia in XY males [PDF]

, 2000
Han N. Lim
openalex   +1 more source

CAG Repeat Not Polyglutamine Length Determines Timing of Huntington’s Disease Onset

Cell, 2019

semanticscholar   +1 more source

Poly-l-Glutamine Forms Cation Channels: Relevance to the Pathogenesis of the Polyglutamine Diseases [PDF]

, 2000
H. Monoi, Shiroh Futaki, Shinichi Kugimiya, Hiroyuki Minakata, Kazuo Yoshihara   +4 more
openalex   +1 more source

Polyglutamine spinocerebellar ataxias — from genes to potential treatments

Nature Reviews Neuroscience, 2017
Henry L. Paulson, V. Shakkottai, H. Clark, Harry T. Orr   +3 more
semanticscholar   +1 more source

Activation of MLK2-mediated Signaling Cascades by Polyglutamine-expanded Huntingtin [PDF]

, 2000
Ya Fang Liu, Donna S. Dorow, John Marshall   +2 more
openalex   +1 more source

Hsp70 and Hsp40 chaperones can inhibit self-assembly of polyglutamine proteins into amyloid-like fibrils [PDF]

, 2000
Paul J. Muchowski, Gregor Schaffar, Annie Sittler, Erich E. Wanker, Manajit Hayer‐Hartl, F. Ulrich Hartl   +5 more
openalex   +1 more source

CREB-binding protein sequestration by expanded polyglutamine [PDF]

, 2000
Alexander McCampbell, J. Paul Taylor, Addis A. Taye, Jon Robitschek, Mei Li, Jessica L. Walcott, Diane E. Merry, Yaohui Chai, Henry L. Paulson, Gen Sobue, Kenneth H. Fischbeck   +10 more
openalex   +1 more source