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Hyperdiverse, bioactive, and interaction-specific metabolites produced only in co-culture suggest diverse competitors may fuel secondary metabolism of xylarialean fungi. [PDF]

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Franco MEE, Nickerson MN, Bowen BP, Louie K, Northen TR, U'Ren JM.   +5 more
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Antibacterial activity of polygodial

Phytotherapy Research, 2005
Polygodial was found to possess moderate antibacterial activity against gram-positive bacteria including Bacillus subtilis, Staphylococcus aureus and gram-negative bacteria including Escherichia coli and Salmonella choleraesuis with minimum bactericidal concentrations (MBC) of 100 and 100 microg/mL (0.34 mm) and 100 and 50 microg/mL, respectively.
Ken-Ichi Fujita, Tae Joung Ha
exaly   +3 more sources

Occurrence of polygodial in plant organs and tissue culture of Polygonum hydropiper

Physiologia Plantarum, 1994
Shoots of Polygonum hydropiper L. (waterpepper), especially in the leaves and flower‐heads, contain significant amounts of the sesquiterpenoid polygodial, a compound with a potential use as a natural pesticide. The polygodial content of the tepals is particularly high: up to 8.5% of the dry weight.
Marc J M Hagendoorn, Linus H W Plas, Teris A Van Beek   +2 more
exaly   +3 more sources

Pharmacological characterisation of the plant sesquiterpenes polygodial and drimanial as vanilloid receptor agonists

Biochemical Pharmacology, 2006
This study was designed to assess the participation of transient receptor potential vanilloid 1 (TRPV1) in the biological effects induced by the plant-derived sesquiterpenes polygodial and drimanial. In rat isolated urinary bladder, polygodial and drimanial produced a tachykinin-mediated contraction that was inhibited by combination of NK(1) and NK(2 ...
Eunice André, Barbara Campi, Juliano Ferreira   +2 more
exaly   +7 more sources

Presence of polygodial and drimenol in Drimys populations from Chile

Biochemical Systematics and Ecology, 2007
Drimys winteri (Winteraceae) is a tree with medicinal properties native to Chile. Its bark contains polygodial and drimenol in unknown quantities, with antimicrobial and antinociceptive activity. The purpose of the present study was to quantify polygodial and drimenol concentrations in leaves of five populations of D.
Diego Munoz-Concha, Hermine Vogel, Angela Malheiros   +2 more
exaly   +2 more sources

Additional evidence for the anti-inflammatory and anti-allergic properties of the sesquiterpene polygodial

Life Sciences, 2001
This study evaluates further the anti-inflammatory and anti-allergic properties of polygodial, a sesquiterpene extracted from the barks plant Drymis winteri (Winteraceae). Polygodial (12.8-128.1 micromol/kg, i.p.) 30 min prior, inhibited significantly the mouse paw oedema induced by prostaglandin E2, bradykinin (BK) substance P (SP), dextran, platelet ...
Fernanda Marques Da Cunha, Tania Silvia Frode, Angela Malheiros   +2 more
exaly   +3 more sources

Polygodial, an Antifungal Potentiator

Journal of Natural Products, 1988
A series of sesquiterpene dialdehydes was isolated from the East African medicinal plants Warburgia stuhlmannii and Warburgia ugandensis (Canellaceae) as antibiotics, particularly against Saccharomyces cerevisiae, Candida utilis, and Sclerotinia libertiana. Among these sesquiterpene dialdehydes, polygodial [1] exhibited the most potent activity.
I, Kubo, M, Taniguchi
openaire   +2 more sources

Antifungal Mechanism of Polygodial

Journal of Agricultural and Food Chemistry, 2001
The primary antifungal action of polygodial comes in part from its ability to function as a nonionic surfactant, disrupting the lipid-protein interface of integral proteins and denaturing their conformation. As a result, the antifungal mechanism of this sesquiterpene dialdehyde is associated with the membrane functions or derangement of the membrane ...
I, Kubo, K, Fujita, S H, Lee
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Synthesis of cinnamolide and polygodial

Journal of the Chemical Society, Chemical Communications, 1981
Starting from 2,6,6-trimethyl-1-vinylcyclohex-1-ene a short synthesis of the sesquiterpenes cinnamolide and polygodial has been achieved with 60% and 57% overall yields, respectively.
S. Christopher Howell, Steven V. Ley, Michael Mahon, Paul A. Worthington   +3 more
openaire   +1 more source

Polygodial: a contact active antifouling biocide

Biofouling, 2014
Ongoing investigation of the candidate antifouling (AF) biocide polygodial (PG) has revealed that this compound may be contact active, whereby it can confer effect while remaining bound within a stable matrix. To test this hypothesis, the AF activity of PG-laced coatings was compared to that of seawater in which PG-laced coatings had been soaked.
P L, Cahill, J M, Kuhajek
openaire   +2 more sources