Results 111 to 120 of about 423 (152)

An Alternative Partial Synthesis of (-)-Polygodial

Synthetic Communications, 1987
Abstract A four steps partial synthesis of (-)-polygodial (1) has been achieved, using (-)-drimenol (2) as starting material.
Iván Razmilic, José López, Jorge Sierra   +2 more
openaire   +1 more source

Synthesis of all possible stereoisomers of polygodial

Tetrahedron Letters, 1984
Abstract The three possible isomers of polygodial, epimers at C-9, cis and trans fused, are described. Controlled kinetic and thermodynamic epimerizations allow preparation of all stereoisomers from the same key intermediate.
D. Guillerm, M. Delarue, M. Jalali-Naini, P. Lemaître, J.-Y. Lallemand   +4 more
openaire   +1 more source

Efficient total syntheses of polygodial and drimenin.

Tetrahedron Letters, 1981
Abstract A short and stereoselective total synthesis of (±) polygodial and drimenin is presented. The efficiency of the synthesis is due to the easy access to intermediate diol 4 and its successful direct oxidation into polygodial.
M. Jallali-Naini, G. Boussac, P. Lemaitre, M. Larcheveque, D. Guillerm, J-Y Lallemand   +5 more
openaire   +1 more source

ChemInform Abstract: SYNTH. VON POLYGODIAL

Chemischer Informationsdienst. Organische Chemie, 1971
AbstractIm Zusammenhang mit der Synthese des aus Polygonum hydropiper isolierten Polygodials (VIII) werden aus Monocyclofamesinsäure (I) die angegebenen Reaktionsprodukte hergestellt.
T. KATO, T. SUZUKI, M. TANEMURA, A. S. KUMANIRENG, N. OTOTANI, Y. KITAHARA   +5 more
openaire   +1 more source

Assessment of Mechanisms Involved in Antinociception Caused by Sesquiterpene Polygodial

The Journal of Pharmacology and Experimental Therapeutics, 2000
Polygodial, a sesquiterpene isolated from the bark of Drymis winteri given systemically, intraplantarly, or by spinal or supraspinal sites, produced antinociception when assessed in both phases of the formalin test and against capsaicin-induced pain. Polygodial, even at high doses, had no antinociceptive or antihyperalgesic effect when assessed in hot ...
G L, Mendes, A R, Santos, A, Malheiros, V C, Filho, R A, Yunes, J B, Calixto   +5 more
openaire   +2 more sources

ChemInform Abstract: SYNTHESIS OF CINNAMOLIDE AND POLYGODIAL

Chemischer Informationsdienst, 1981
AbstractDas Trimethylvinylcyclohexen (I) reagiert mit dem Acetylen (II) zum Cycloaddukt (III), das in Gegenwart von Spuren Salzsäure zum Monoen (IV) hydriert wird.
S. C. HOWELL, S. V. LEY, M. MAHON, P. A. WORTHINGTON   +3 more
openaire   +1 more source

Incorporation of polygodial in Langmuir films of selected lipids

Thin Solid Films, 2019
Abstract Identification of membrane sites capable of drug binding is important to understand the interaction of bioactive compounds with biointerfaces such as microbial cellular membranes. As the exact molecular mechanism of action is yet to be fully understood for many drugs, in this study, polygodial, an antimicrobial compound, was incorporated in ...
Giulia Elisa G. Gonçalves, Thiago R. Morais, João Henrique G. Lago, Luciano Caseli   +3 more
openaire   +1 more source

Identification of an intermediate in the reaction between polygodial and methylamine in biomimetic conditions

Tetrahedron Letters, 1984
Abstract The intermediate 2 has been identified, by spectral means, in the course of the reaction in biomimetic conditions between polygodial (1) and methylamine leading to the pyrrole derivative 3.
G. Cimino, SPINELLA, Aldo, G. Sodano
openaire   +2 more sources

Determination of the sesquiterpene dialdehyde polygodial by high‐pressure liquid chromatography

Phytochemical Analysis, 1994
AbstractA high‐pressure liquid chromatographic procedure for the determination of the antifeedant polygodial in Polygonum hydropiper leaves was developed. For leaves, the method consists of a selective extraction with hexane: EtOAc (8:2), pre‐purification of the evaporated extract over a solid phase C2 column, separation with a C18 RP‐HPLC column and ...
van Beek, T.A., van Dam, N., de Groot, Æ., Geelen, T.A.M., van der Plas, L.H.W.   +4 more
openaire   +2 more sources

The conversion of (−)- and (+)-dihydrocarvone into chiral intermediates for the synthesis of (−)-polygodial, (−)-warburganal and (−)-muzigadial

Tetrahedron, 1989
Abstract (−)-Dihydrocarvone was converted into (−)-(4aR, 8aR)-3,4,4a,5,6,7,8,8a-octahydro-4a, 8,8-trimethylnaphthalene-2(H)-one (1) via an efficient route in which a Wolff-Kishner reduction, accompanied with a double bond isomerisation brought on a major simplification. Ketone 1 is a suitable intermediate for the syntheses of the insectantifeedants (−
Jansen, B.J.M., Kreuger, J.A., de Groot, Ae.   +2 more
openaire   +2 more sources