Bioassay-guided isolation of three anthelmintic compounds from Warburgia ugandensis Sprague subspecies ugandensis, and the mechanism of action of polygodial [PDF]
Parasitic helminths continue to pose problems in human and veterinary medicine, as well as in agriculture. Resistance to current anthelmintics has prompted the search for new drugs.
Dhondt, InekeUGent0020052992858020008172609799090252960000-0001-5162-706304C524EA-F0EE-11E1-A9DE-61C894A0A6B4 +10 more
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The Structure of Polygodial: A New Sesquiterpene Dialdehyde from Polygonum hydropiper L [PDF]
A pungent substance, polygodial, isolated from Polygonum hydropiper L. is shown to be drim-7-en-11,12-dial (I), a new dialdehyde structurally related to sesquiterpene lactones from Drimys species.
CS Barnes, JW Loder
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Improving the Extraction Potential of Polygodial from Horopito using Pulsed Electric Field and Deep Eutectic Solvent [PDF]
Full text is available to authenticated members of The University of Auckland only.New Zealand is a country with a variety of unique flora and fauna due to its geographically isolated position. One of them is horopito (Pseudowintera colorata), an ancient
Nadia, Joanna
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Identification of an Intermediate in the Reaction Between Polygodial and Methylamine in Biomimetic Conditions. [PDF]
The intermediate 2 has been identified, by spectral means, in the course of the reaction in biomimetic conditions between polygodial (1) and methylamine leading to the pyrrole derivative 3
G. Sodano +3 more
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Insecticidal action of Drimys brasiliensis Miers on black citrus aphid
The aim of this study was to evaluate the insecticidal effects of a hexane fraction and polygodial compound obtained from Drimys brasiliensis roots on the mortality of adults and nymphs of Toxoptera citricida (black citrus aphid). For the hexane fraction,
Simoni Anese +3 more
doaj +1 more source
Anti-leishmanial and anti-trypanosomal potential of polygodial isolated from stem barks of Drimys brasiliensis Miers (Winteraceae) [PDF]
Parasitic protozoan diseases affect the poorest population in developing countries. Leishmaniasis and Chagas disease have been included among the most important threats for public health in Central and South American continent, with few therapeutic ...
Lago, Joao Henrique G. [UNIFESP] +17 more
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The potential use of pulsed electric field to assist in polygodial extraction from Horopito (Pseudowintera colorata) leaves [PDF]
Horopito (Pseudowintera colorata) contains polygodial as an active compound that has many health beneficial properties. The potential of applying a continuous pulsed electric field (PEF) as a pretreatment step prior to solvent extraction of polygodial ...
Farid, Mohammed +3 more
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Effect of polygodial and its direct derivatives on the mammalian Na+/K+-ATPase activity [PDF]
The sesquiterpene polygodial is an agonist of the transient receptor potential vanilloid 1 (TRPV1). Our group recently reported the synthesis and anticancer effects of polygodial and its derivatives, and showed that these compounds retain activity ...
Camila Ignácio da Silva +15 more
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Plant nutrition, growth and polygodial production of Tasmannia lanceolata [PDF]
Rapid growth of some native Australian plant species can be achieved by targeted applications of selected nutrients. The aim of this study was to examine the influence of nutrient levels on early establishment of Tasmannia lanceolata (Winteraceae) for ...
Matthew Wilson (14753053) +2 more
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Polygodial, a sesquiterpene isolated from Drimys brasiliensis (Winteraceae), triggers glucocorticoid-like effects on pancreatic beta-cells [PDF]
Despite its common use, the synthetic glucocorticoid dexamethasone can cause several adverse effects, such as diabetes and insulin-related metabolic impairment.
Barrosa, Kaidu Hanashiro [UNIFESP] +9 more
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