Results 91 to 100 of about 29,306 (220)

Immunosenescence Profile Is Associated With Increased Susceptibility to Severe COVID‐19

Aging Cell, EarlyView.
(A) A previous immunosenescence profile in individuals infected with SARS‐CoV2 creates a permissive environment for progression to severe COVID‐19: higher inflammaging, accumulation of exhausted/senescent T cells, an oligoclonal B‐cell repertoire, and accelerated epigenetic age.
Lucas Haniel A. Ventura, Lícia Torres, Giovanna Caliman Camatta, Jofer Zamame, Monique Macedo Coelho, Cecília Horta Ramalho‐Pinto, João Gervazio, Felipe Caixeta, Leandro Nascimento, Mariana Almeida Oliveira, Vinícius Dantas Martins, Marcos Felipe Oliveira, Murilo Soares Costa, Hugo Itaru Sato, Henrique Cerqueira Guimarães, Rafael Calvão Barbuto, Ana Paula Rocha Veiga, Najara Ataíde, Gabriela Prandi Caetano, Sarah Rangon, Mauro Lúcio O. Júnior, Fernanda Calvo Fortes, Luciana Zuccherato, Elaine Speziali, Olindo Assis Martins‐Filho, Verônica Coelho, Roberto Avritchir, Rafael Souza, Marina Ayupe, Caio Loureiro, Maria Eduarda Passos, Ana Clara Mota Neves, Pauline Leite, Santuza Maria Ribeiro Teixeira, Unaí Tupinambás, Liza Figueiredo Felicori, Gabriela Silveira‐Nunes, Tatiani Uceli Maioli, Denise Morais Fonseca, Andrea Teixeira‐Carvalho, Ana Maria Caetano Faria   +40 more
wiley   +1 more source

Ythdf2 Ablation Protects Aged Retina From RGC Dendrite Shrinking and Visual Decline

Aging Cell, EarlyView.
The m6A reader YTHDF2 regulates retinal degeneration caused by aging, which is mediated by its target mRNAs Hspa12a and Islr2. ABSTRACT Aging‐related retinal degeneration and vision loss have been severely affecting the elderly worldwide. Previously, we showed that the m6A reader YTHDF2 is a negative regulator for dendrite development and protection of
Fugui Niu, Gaoxin Long, Jian Zhang, Jun Yu, Sheng‐Jian Ji   +4 more
wiley   +1 more source

A data structure to represent data sets with more than one order relation like polygons [PDF]

, 2017
Cardona Sanchez, Duvan, Trujillo, Edwin Rivas, Verdesoto, Edgardo Samuel Barraza   +2 more
core   +1 more source

Substitutes or complements? The effect of opening a food store on customer visits to neighborhood food stores

American Journal of Agricultural Economics, EarlyView.
Abstract This study examines the effects of new food store openings on customer traffic to incumbent stores using a modified difference‐in‐differences approach and cellphone location data from the contiguous United States in 2019. Analysis of both the intensive margin (total visit counts) and the extensive margin (unique visitors) reveals substantial ...
Modhurima Dey Amin, Syed Badruddoza, Jill J. McCluskey   +2 more
wiley   +1 more source

The necessity of motoric engagement in enhancing route memory

British Journal of Psychology, EarlyView.
Abstract The relative contribution of decision‐making and motor engagement at encoding, on route memory, was examined using virtual reality (VR). During encoding, participants explored 12 virtual environments for 40 s each. Navigation strategy during encoding was manipulated within‐subjects.
Yadurshana Sivashankar, Philip He, Patrick Tsapoitis, Evan Skorski, Myra A. Fernandes   +4 more
wiley   +1 more source

Quantitative T1 is sensitive to cortical remyelination in multiple sclerosis: A postmortem MRI study

Brain Pathology, EarlyView.
In a post‐mortem study using multiparametric qMRI of whole fixed human brains from people with multiple sclerosis (pwMS), we found evidence that quantitative T1 (qT1) is sensitive to remyelination in the cortex. In contrast, QSM and radial diffusivity were affected by cortical pathology independently of remyelination. Our data suggest that qT1 could be
Riccardo Galbusera, Matthias Weigel, Erik Bahn, Sabine Schaedelin, Alessandro Cagol, Po‐Jui Lu, Muhamed Barakovic, Lester Melie‐Garcia, Jonas Franz, Peter Dechent, Govind Nair, Ludwig Kappos, Wolfgang Brück, Christine Stadelmann, Cristina Granziera   +14 more
wiley   +1 more source

Diversity of U1 Small Nuclear RNAs and Diagnostic Methods for Their Mutations

Cancer Science, EarlyView.
Complex interindividual U1 snRNA diversity was unveiled. Mutations in such complex loci were precisely detected with a pangenome graph reference, which enhances the possibility of the human pangenome reference in cancer genomics. ABSTRACT U1 small nuclear RNA (snRNA) mutations are recurrent non‐coding alterations found in various malignancies, yet ...
Takuma Nakashima, Tsubasa Miyauchi, Ryota Takeuchi, Yuriko Sugihara, Yusuke Funakoshi, Fumiharu Ohka, Sachi Maeda, Junko Hirato, Takako Yoshioka, Hajime Okita, Yoshitaka Narita, Yonehiro Kanemura, Yasuhiro Kojima, Yuko Watanabe, Ryuta Saito, Hiromichi Suzuki   +15 more
wiley   +1 more source

Neural Geometry Processing via Spherical Neural Surfaces

Computer Graphics Forum, EarlyView.
Abstract Neural surfaces (e.g., neural map encoding, deep implicit, and neural radiance fields) have recently gained popularity because of their generic structure (e.g., multi‐layer perceptron) and easy integration with modern learning‐based setups. Traditionally, we have a rich toolbox of geometry processing algorithms designed for polygonal meshes to
Romy Williamson, Niloy J. Mitra
wiley   +1 more source

Isosurface Extraction for Signed Distance Functions using Power Diagrams

Computer Graphics Forum, EarlyView.
Abstract Contouring an implicit function typically considers function values in the vicinity of the desired level set, only. In a recent string of works, Sellán at al. have demonstrated that signed distance values contain useful information also if they are further away from the surface.
M. Kohlbrenner, M. Alexa
wiley   +1 more source

S‐ACORD: Spectral Analysis of COral Reef Deformation

Computer Graphics Forum, EarlyView.
Abstract We propose an efficient pipeline to register, detect, and analyze changes in 3D models of coral reefs captured over time. Corals have complex structures with intricate geometric features at multiple scales. 3D reconstructions of corals (e.g., using Photogrammetry) are represented by dense triangle meshes with millions of vertices.
Naama Alon‐Borissiouk, Matan Yuval, Tali Treibitz, Mirela Ben‐Chen   +3 more
wiley   +1 more source