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Effects of Polygonum multiflorum on the activity of cytochrome P450 isoforms in rats
Die Pharmazie, 2015Polygonum multiflorum is a traditional Chinese medicinal herb used in clinical medicine to nourish the liver and kidney. However, in recent years, there have been increased reports of clinical adverse reactions associated with Polygonum multiflorum preparations, especially due to liver injury.
Yuan Zhang, Yuan Zhang +4 more
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Anti-HIV Activities of the Compounds Isolated fromPolygonum cuspidatumandPolygonum multiflorum
Planta Medica, 2010The 70 % EtOH extract of Polygonum cuspidatum showed inhibitory action against HIV-1-induced syncytium formation at non-cytotoxic concentrations in vitro with a 50 % effective concentration (EC(50)) of 13.94 +/- 3.41 microg/mL. Through bioactivity-guided fractionation, 20 phenolic compounds, including eight stilbenoids, were isolated from the roots of ...
Hong-Wei, Lin +10 more
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Exploration research on hepatotoxic constituents from Polygonum multiflorum root
China Journal of Chinese Materia Medica, 2016By observing the cytotoxic effects of anthraquinones on HepG2 cell and using the precision-cut liver slices technique to authenticate the cytotoxic constituents, the paper aims to explore the material basis of Polygonum multiflorum root to cause liver toxicity.
Min, Yang +8 more
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[Toxic hepatitis induced by Polygonum multiflorum].
Vnitrni lekarstvi, 2013Toxic liver injury is a common cause of acute hepatitis. Here we report a case of 33-year old female with toxic hepatitis caused by unusual agent- extract of chinese plant Polygonum multiflorum. The patient presented with clinical signs of nausea and icterus and laboratory signs of hepatocellular damage following 2 months of readministration of ...
A, Banarova, T, Koller, J, Payer
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[Studies on the chemical constituents of the leaves of Polygonum multiflorum].
Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials, 2009To study the chemical constituents of the leaves of Polygonum multiflorum.The chemical constituents were extracted with water and separated by manifold chromatography technique, and their structures were determined by spectral analysis.Eleven compounds were isolated and identified as physcion (I), emodin (II), noreugenin (III), apigenin (IV ...
Gao-Xiong, Rao +4 more
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Chemical Constituents of Polygonum multiflorum Leaves
Chemistry of Natural Compounds, 2023Fan Yang +6 more
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