Results 81 to 90 of about 16,615 (159)

2,2-Diphenyl-1-picrylhydrazyl radical-scavenging active components from Polygonum multiflorum Thunb.

, 1999
An activity-directed fractionation and purification process was used to identify the antioxidative components of Polygonum multiflorum Thunb. (PM). Dried root of PM was extracted with 95% ethanol and then separated into water, ethyl acetate, and hexane ...
Ho, CT, Rosen, RT, Wang, M, Chen, Y
core   +1 more source

Sustainable valorization of functional phytochemicals from Polygonum multiflorum using natural deep eutectic solvents (NADES)

Industrial Crops and Products
This study applied a natural deep eutectic solvent (NADES) consisting of malic acid and choline chloride for bioactive compound extraction from Reynoutria multiflora (Thunb.) Moldenke (syn.
Kyeong-Ok Choi, Yeongjun Ban, Youngmin Kang   +2 more
doaj   +1 more source

Inhibition of Mitochondrial Complex Function—The Hepatotoxicity Mechanism of Emodin Based on Quantitative Proteomic Analyses

Cells, 2019
Emodin is the main component of traditional Chinese medicines including rhubarb, Polygonum multiflorum, and Polygonum cuspidatum. It has confirmed hepatotoxicity and may be the main causative agent of liver damage associated with the above-mentioned ...
Longfei Lin, Yuling Liu, Sai Fu, Changhai Qu, Hui Li, Jian Ni   +5 more
doaj   +1 more source

Stilbenes with Potent Protein Tyrosine Phosphatase-1B Inhibitory Activity from the Roots of Polygonum multiflorum

, 2020
Seven new stilbene glycosides including three dimers (1–3) and four monomers (4–7) were isolated from the roots of Polygonum multiflorum along with nine previously identified stilbenes (8–16).
Jeong Ah Kim, Thi-Thuy An Nguyen (8313795), Manh Tuan Ha (8313798), Se-Eun Park, Se-Eun Park (2729752), Jae Sue Choi (2008516), Byung Sun Min (2008513), Thi-Thuy An Nguyen, Manh Tuan Ha, Jae Sue Choi, Byung Sun Min, Jeong Ah Kim (2348359)   +11 more
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Phytochemistry, pharmacology, toxicology and detoxification of Polygonum multiflorum Thunb.: a comprehensive review

Frontiers in Pharmacology
BackgroundPolygonum multiflorum Thunb. (PM), a kind of perennial plant, belongs to the genus Polygonum of the family polygonaceae.The dry root of PM (also called Heshouwu), is a traditional Chinese medicine, which has a series of functions and is widely ...
Jiawen Qian, Chenhang Feng, Ziyang Wu, Yuanmei Yang, Xiangfu Gao, Lingyan Zhu, Yang Liu, Yuancheng Gao   +7 more
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Potential Antioxidant Components and Characteristics of Fresh Polygonum multiflorum

, 2014
The leaf, stem and root of fresh Polygonum multiflorum plant were investigated. The contents of bioactive compounds and their antioxidant potential were studied by several radicals scavenging assay, and the antioxidative substances measured.
Huang, Y.Y., Wu, S.C., Lin, H.T., Nah, S.L.   +3 more
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Myocardial protection against ischaemia-reperfusion injury by a Polygonum multiflorum extract supplemented 'Dang-Gui Decoction for Enriching Blood', a compound formulation, ex vivo

, 2000
'Dang-Gui Decoction for Enriching the Blood' (BE), a traditional Chinese formulation comprising Angelica sinensis and Astragalus membranaceus, is used for stimulating red blood cell production as well as enhancing cardiovascular function.
Yim, T. K., Ko, K. M., Mak, D. H.F., Liang, S. M., Pak, W. F., Wu, W. K.   +5 more
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Precise subcellular organelle-targeted analyses of hepatotoxicity of Polygonum multiflorum

Chinese Herbal Medicines
Drug-induced liver injury (DILI) is an undesirable reaction caused by drugs, herbal medicines or supplements and may lead to acute liver failure. Polygoni Multiflori Radix (PMR, Heshouwu in Chinese) originated from the roots of Polygonum multiflorum is a popular traditional Chinese medicine (TCM) while potential hepatotoxicity limits its clinical ...
Li, Yijie, Duan, Shuni, Zhang, Yinhao, Liu, Runping, Sun, Rong, Wu, Jianzhi, Ma, Zhi, Li, Xiaojiaoyang   +7 more
openaire   +2 more sources

Components synergy between stilbenes and emodin derivatives contributes to hepatotoxicity induced by Polygonum multiflorum

, 2019
Polygonum multiflorum Thunb. (PM) is a famous traditional Chinese medicine with liver tonic effect, but arousing great concerns for hepatotoxicity issue.
Chunyu Li (437902), Xiaoyi Liu (572510), Le Zhang (88249), Youping Liu (90164), Jiabo Wang (5369771), Ruisheng Li (740516), Xiaohe Xiao (6536402), Can Tu (6557783), Yuanyuan Zhou (389970), Xiaohui Wang (19899), Jingxiao Zhu (7335467), Di Song (1325301)   +11 more
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Polydatin in respiratory diseases: multi-target mechanisms and therapeutic potential

Frontiers in Pharmacology
Respiratory diseases constitute a heterogeneous group of disorders that primarily involve the lungs. Driven by worsening air pollution, tobacco use, occupational exposures, the COVID-19 pandemic, and population aging, they show persistently high ...
Chanjun Wan, Chanjun Wan, Xinyang Liu, Yueqi Xu, Yueqi Xu, Li Kang, Xuelong Yu, Min Wang, Min Zhao, Xinhan Li, Zhengtao Chen, Jianguang Wu, Liangji Liu, Xuemei Xu, Xuemei Xu   +14 more
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