Results 71 to 80 of about 517 (172)

Visualization of Biogenic Amines and In Vivo Ratiometric Mapping of Intestinal pH by AIE‐Active Polyheterocycles Synthesized by Metal‐Free Multicomponent Polymerizations

, 2019
Acid-base homeostasis is crucial for normal physiology, metabolism, and functions of living organisms. Thus, the development of effective techniques to monitor it either in vitro or in vivo is in great demand.
Ting Han, Wen‐Xiong Wang, Ben Zhong Tang, Liu, Xiaolin, Wang, Wen Xiong, Han, Ting, Lam, Jacky W.Y., Yan, Neng, Liu, Junkai, Jacky W. Y. Lam, Yubing Hu, Junkai Liu, Xiaolin Liu, Neng Yan, Hu, Yubing, Tang, Ben Zhong   +15 more
core   +1 more source

Photoassisted Synthesis of Complex Polyheterocycles via Rational Design of Tailored Photoprecursors

, 2021
Natural products remain the most common source for drug leads, although diversity-oriented synthesis of unnatural complex molecules is gaining momentum. Our lab has been developing experimentally simple and straightforward approaches to complex molecular
Holt, Tina Alanna
core  

Photoassisted Synthesis of Complex Polyheterocycles via ESIPT-Driven Dearomative Intramolecular Cycloadditions

, 2019
This research is focused on the development of novel photoassisted synthetic methodologies that provide straightforward access to complex and diverse libraries of polyheterocycles from modularly assembled precursors.
Kuznetsov, Dmitry
core  

Metal-Free Multicomponent Tandem Polymerizations of Alkynes, Amines, and Formaldehyde toward Structure- and Sequence-Controlled Luminescent Polyheterocycles

, 2017
Sequence-controlled polymers, including biopolymers such as DNA, RNA, and proteins, have attracted much attention recently because of their sequence-dependent functionalities.
Zhao, Zujin, Weizhang Li, Bo Wei, Anjun Qin, Rongrong Hu, Ben Zhong Tang, Qin, Anjun, Li, Weizhang, Zujin Zhao, Hu, Rongrong, Wei, Bo, Tang, Ben Zhong   +11 more
core   +1 more source

Tandem Rh(III)-Catalyzed C–H Heteroarylation of Indolyl Ketones and Cu(II)-Promoted Intramolecular Cyclization: One-Pot Access to Blue-Emitting Phenanthrone-Type Polyheterocycles

, 2019
Disclosed herein is a highly efficient one-pot synthetic strategy to phenanthrone-type polyheterocycles via tandem rhodium­(III)-catalyzed ortho-C–H heteroarylation of indolyl ketones and copper­(II)-promoted intramolecular cyclization.
Yudong Yang (185767), Zheng Liu (28397), Mangang Zhang (6292814), Wenbo Liang (2882534), Jingsong You (1397368), Xingwen Pu (6292811), Shuyou Chen (1909381), Jingbo Lan (1452568), Min Zhang (111999)   +8 more
core   +1 more source

Polyheterocyclic peptidomimetics: Parallel solid phase synthesis of oligo cyclic guanidines and their inhibition activity against Mycobacterium tuberculosis DNA gyrase. [PDF]

Bioorg Med Chem Lett, 2023
Tantak M, Rayala R, Deng Z, Bunnell A, Wang T, Chaudhari P, Leng F, Nefzi A.   +7 more
europepmc   +1 more source

Highly Stereoselective Ugi/Pictet-Spengler Sequence. [PDF]

J Org Chem, 2022
Zhang B, Kurpiewska K, Dömling A.
europepmc   +1 more source

Photoassisted Generation of Complex N, O, S Polyheterocycles

, 2016
This research set out to continue the exploration and diversification of excited state o-azaxylylene cycloadditions, utilizing both pre-photochemical and post-photochemical modifications.
Umstead, Weston James
core  

Synthesis of Multiring Fused 2-Pyridones via a Nitrene Insertion Reaction: Fluorescent Modulators of α-Synuclein Amyloid Formation

, 2015
© 2015 American Chemical Society. An efficient, straightforward method for the synthesis of thiazolo-2-pyridone embedded peptidomimetic polyheterocycles via a catalyst-free, microwave-assisted, intramolecular C-H amination reaction is reported.
Pardeep Singh (294895), Singh, P., Almqvist, F., K. Syam Krishnan (1493944), Wittung Stafshede, Pernilla, Erik Chorell (813073), Chorell, E.,, Kindahl, T., Kindahl, T.,, Åden, J.,, Wittung-Stafshede, Pernilla, Almqvist, F.,, Chorell, E., Krishnan, K.S., Åden, J., Tomas Kindahl (1493947), Fredrik Almqvist (698391), Krishnan, K.S.,, Singh, P.,, Pernilla Wittung-Stafshede (166503), \uc5den, J., Jörgen Åden (1493950), Wittung Stafshede, Pernilla,   +22 more
core   +1 more source

Diversity-Oriented Synthesis of Ketoindoloquinoxalines and Indolotriazoloquinoxalines from 1‑(2-Nitroaryl)-2-alkynylindoles

, 2016
A one-pot protocol for the diversity-oriented synthesis of two indole-based annulated polyheterocycles, ketoindoloquinoxalines and indolotriazoloquinoxalines, has been described.
Srinivas Samala (1830718), Bijoy Kundu (1830715), Rajesh K Arigela (1830721), Ruchir Kant (1433839)   +3 more
core   +1 more source