Results 91 to 100 of about 24,230,330 (112)

Liposome drug delivery strategies: state-of-the-art for combating bacterial biofilms. [PDF]

open access: yesFront Microbiol
Lin T   +9 more
europepmc   +1 more source

Characteristics of the Molecular Weight of Polyhexamethylene Guanidine (PHMG) Used as a Household Humidifier Disinfectant [PDF]

open access: yesMolecules, 2021
(1) Background: Household humidifier disinfectant (HD) brands containing polyhexamethylene guanidine (PHMG) have been found to cause the most HD-associated lung injuries (HDLIs) in the Republic of Korea.
Han Bin Oh, Ju-Hyun Park, So-Yeon Lee
exaly   +3 more sources

Integration of transcriptomics, proteomics and metabolomics identifies biomarkers for pulmonary injury by polyhexamethylene guanidine phosphate (PHMG-p), a humidifier disinfectant, in rats

Archives of Toxicology, 2020
Polyhexamethylene guanidine phosphate (PHMG-p) was used as a humidifier disinfectant in Korea. PHMG induced severe pulmonary fibrosis in Koreans. The objective of this study was to elucidate mechanism of pulmonary toxicity caused by PHMG-p in rats using multi-omics analysis.
Su Hyun Lee   +2 more
exaly   +3 more sources

Guanidine-based disinfectants, polyhexamethylene guanidine-phosphate (PHMG-P), polyhexamethylene biguanide (PHMB), and oligo(2-(2-ethoxy)ethoxyethyl guanidinium chloride (PGH) induced epithelial-mesenchymal transition in A549 alveolar epithelial cells

Inhalation Toxicology, 2019
Abstracts Objective: The major active ingredient of humidifier disinfectant, polyhexamethylene guanidine-phosphate (PHMG-P), caused hundreds of deaths with pulmonary fibrosis. However, structurally similar guanidine-based disinfectants are still in use in various fields.
Yong Joo Park   +2 more
exaly   +3 more sources

eDNA Inactivation and Biofilm Inhibition by the PolymericBiocide Polyhexamethylene Guanidine Hydrochloride (PHMG-Cl) [PDF]

open access: yesInternational Journal of Molecular Sciences, 2022
The choice of effective biocides used for routine hospital practice should consider the role of disinfectants in the maintenance and development of local resistome and how they might affect antibiotic resistance gene transfer within the hospital ...
Olga Iungin   +2 more
exaly   +2 more sources

Properties of Polyhexamethylene Guanidine (PHMG) Associated with Fatal Lung Injury in Korea

open access: yesMolecules, 2020
The use of humidifier disinfectant (HD) has been determined to be associated with lung injuries (HDLI) in Korea. Although HD brands containing polyhexamethylene guanidine (PHMG) oligomers have been found to cause more HDLI compared to brands containing ...
Han Bin Oh, Ju-Hyun Park, Jihoon Park
exaly   +2 more sources

Respiratory Toxicity of Polyhexamethylene Guanidine Phosphate Exposure in Zebrafish

open access: yesZebrafish, 2018
Humidifier disinfectants containing polyhexamethylene guanidine phosphate (PHMG-P) can induce pulmonary toxicity and has caused human casualties in South Korea since 2006.
Bokyeong Ryu   +2 more
exaly   +2 more sources

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