Polyhexanide-Releasing Membranes for Antimicrobial Wound Dressings: A Critical Review
The prevalence of chronic, non-healing skin wounds in the general population, most notably diabetic foot ulcers, venous leg ulcers and pressure ulcers, is approximately 2% and is expected to increase, driven mostly by the aging population and the steady ...
António Jorge Guiomar, Ana M. Urbano
doaj +4 more sources
Pathogen- and Host-Directed Antileishmanial Effects Mediated by Polyhexanide (PHMB). [PDF]
BACKGROUND:Cutaneous leishmaniasis (CL) is a neglected tropical disease caused by protozoan parasites of the genus Leishmania. CL causes enormous suffering in many countries worldwide. There is no licensed vaccine against CL, and the chemotherapy options
Rebuma Firdessa +11 more
doaj +11 more sources
Impact of Polyhexanide Care Bundle on Surgical Site Infections in Paediatric and Neonatal Cardiac Surgery: A Propensity Score-Matched Retrospective Cohort Study. [PDF]
The primary aim of this study was to evaluate the impact of the polyhexamethylene biguanide (PHMB) care bundle on the occurrence rates of surgical site infections (SSIs) in paediatric and neonatal cardiac surgery, addressing a critical gap in paediatric ...
Castiello G +13 more
europepmc +3 more sources
Polyhexanide, Povidone-Iodine, and Hypochlorous Acid Show High In Vitro Antimicrobial Efficacy Against Pathogens Commonly Associated With Equine Infectious Keratitis. [PDF]
Objective To determine the in vitro antimicrobial activity of specific antiseptics against common equine ocular surface pathogens. Methods Staphylococcus aureus ( S. aureus ) (n = 12), Streptococcus equi subspecies zooepidemicus (S. zooepidemicus) (n = 9)
Stolle LM +7 more
europepmc +3 more sources
Wound infection is a common complication of chronic wounds. It can impair healing, which may not occur without external help. Antimicrobial dressings (AMDs) are a type of external help to infected chronic wounds.
Luís M. Vaz +3 more
doaj +4 more sources
Analysis of the chemical interaction of polyhexanide with endodontic irrigants
INTRODUCTION. Chronic apical periodontitis (CAP) poses significant challenges in endodontics due to microbial resistance and inadequate disinfection protocols. Polyhexanide (PHMB) is a promising irrigant due to its antimicrobial properties.
Z. S. Zurab +6 more
doaj +3 more sources
Polyhexanide (PHMB) – properties and applications in medicine [PDF]
Polyhexamethylene biguanide (PHMB) is one of the many antiseptics available in the medicine. It stands out from the others with its numerous advantages.
Patrycja Szkołuda, Tomasz M. Karpiński
doaj +4 more sources
Polyhexanide as a new antiseptic composition for a dentist
Aim. To assess systematically the available scientific evidence about clinical response of using polyhexanide as an antiseptic agent in medicine and dentistry.
Z. S. Khabadze +5 more
doaj +3 more sources
Polyhexanide and chlorhexidine loaded chitosan wound dressings [PDF]
Introduction Wounds may be caused by surgery, trauma, or as a result of diseases such as diabetes. The disruption of the skin/internal tissues and the contact with the external environment may lead to microbial infection.
Eleni Nydrioti +2 more
doaj +2 more sources
A Comparative Study to Evaluate the Effectiveness between Synergic Activities of 0.1% Polyhexanide and Rigenase® (Fitostimoline® Plus spray) versus a Hydrating Formulation for the Topical Management of Rubbing Injuries Secondary to Atopic Dermatitis. [PDF]
Introduction Managing rubbing injuries in atopic dermatitis is challenging and has a significant impact on patients’ quality of life. Polyhexamethylene biguanide (PHMB) and Rigenase® (a patented Triticum vulgare extract) show promise in tissue repair and
Di Brizzi EV +5 more
europepmc +2 more sources

