Results 51 to 60 of about 2,536 (211)

Bacterial Growth Kinetics under a Novel Flexible Methacrylate Dressing Serving as a Drug Delivery Vehicle for Antiseptics [PDF]

, 2013
A flexible methacrylate powder dressing (Altrazeal®) transforms into a wound contour conforming matrix once in contact with wound exudate. We hypothesised that it may also serve as a drug delivery vehicle for antiseptics.
Archibald, Assadian, Axel Kramer, Beldon, Braga, Chen, Christina Forstner, Clark, Cutting, David Leaper, Deitch, Disemond, Eberlein, Fang, Fitzgerald, Henry-Stanley, Hirsch, Johannes Leitgeb, Keith Cutting, Kim, Lalani, Leaper, Leaper, Migliaresi, Minnich, Nathan, Nordmann, Ojan Assadian, Rupert Schuster, Sibbald, Tsou, Vanscheidt, Verena Dosch, Wang, Winter   +34 more
core   +4 more sources

Safety assessment of Polyhexamethylene biguanide [PDF]

International Journal of Medical Device and Adjuvant Treatments, 2019
OBJECTIVE: The use of antiseptics in the treatment of genital infections has become a systematic alternative to antibiotics. Their use has been also supported for the treatment of virus-induced genital infections.
B. Orrù, P. Lista, M. Bertelli, V. Unfer   +3 more
doaj   +1 more source

Impact of exposure of methicillin-resistant Staphylococcus aureus to polyhexanide in vitro and in vivo. [PDF]

, 2017
Staphylococcus aureus (MRSA) resistant to decolonization agents such as mupirocin and chlorhexidine increase the need to develop alternative decolonization molecules.
Abdelhady, W, Baud, D, Bayer, A, Bonetti, EJ, Cherkaoui, A, Diene, SM, François, P, Gonzales, R, Harbarth, S, Landelle, C, Manzano, C, O'Neill, AJ, Randall, CP, Renzoni, A, Schrenzel, J, Von Dach, E   +15 more
core   +3 more sources

Anti-Biofilm Effect of Octenidine and Polyhexanide on Uropathogenic Biofilm-Producing Bacteria [PDF]

Urologia Internationalis, 2021
<b><i>Background:</i></b> A catheter allowing a release of antibacterial substances such as antiseptics into the bladder could be a new way of preventing biofilm formation and subsequent catheter-associated urinary tract infections. <b><i>Methods:</i></b> Minimal inhibitory and bactericidal concentration (
Maria Loose, Kurt G. Naber, Larry Purcell, Manfred P. Wirth, Florian M.E. Wagenlehner   +4 more
openaire   +3 more sources

Antibiotics and antiseptics for pressure ulcers [PDF]

, 2016
Background: Pressure ulcers, also known as bedsores, decubitus ulcers and pressure injuries, are localised areas of injury to the skin or the underlying tissue, or both. A range of treatments with antimicrobial properties, including impregnated dressings,
Allman, Allman, Anzai, Baker, Baker, Bale, Bazzigaluppi, Becker, Beele, Bennett, Bergstrom, Berlowitz, Bigolari, Bonita, Bowler, Bowler, Braga, Brandeis, Cammen, Carville, Cataldo, Chirwa, Chuangsuwanich, Chuangsuwanich, Coleman, Colombo, Cutting, Darbas, Davies, Dealey, Della Marchina, Dowd, Dumville, Dumville, Edwards, Ellis, Essex, EuroQuoL Group, Gardner, Garibaldi, Gebhardt, Gefen, Gerding, Goldmeier, Gorecki, Gorse, Graves, Haesler, Hahn, Halbert, Hall, Hansson, Hartman, Helaly, Heym, Higgins, Horan, Howell-Hones, Howell-Jones, Imamura, Ishibashi, Itani, Jull, Kaya, Kim, Kingsley, Kontopantelis, Kontopantelis, Konychev, Kucan, Kuroyanagi, Laat, Lazareth, Lee, LeVasseur, Liberati, Loerakker, Macpherson, Madsen, McGinnis, McInnes, Meaume, Meaume, Moberg, Moore, Moore, Moore, Motta, Munter, Nicolle, Nisi, O'Meara, Parish, Parish, Parmar, Percival, Power, Prentice, Price, Raghaven, Reddy, Rhodes, Robson, Romanelli, Royal Pharmaceutical Society of Great Britain, Saha, Sanada, Sapico, Saydak, Scalise, Schulz, Serra, Shrivastava, Sibbald, Sipponen, Sipponen, Smith, Smith, Sotto, Stevens, Stevenson, Storm-Versloot, Teot, Thomas, Thompson, Thompson, Tierney, Toba, Trengove, Vanderwee, VanGilder, Vermeulen, Vermeulen, Wang, Ware, Weheida, Wild, Wolcott, World Union of Wound Healing Societies, Worsley, Yapucu Güneş, Yastrub, Yura, Zeron, Zhao   +144 more
core   +1 more source

A novel approach to antibiofilm susceptibility testing using a thermo-reversible matrix [PDF]

, 2016
Method: Pseudomonas aeruginosa (NCIMB 8626) was cultured in medium containing poloxamer 407 at 37°C for 24 hours to generate biofilms. The preparation was cooled to liquefy the poloxamer and allow recovery of the biofilm cells, which were then stained
Benjamin, Taylor,, Jonathan, Nosworthy, Marsh, Lucy L., Williams, David   +3 more
core   +2 more sources

MRSA decolonization failure - are biofilms the missing link? [PDF]

, 2017
Background: Device-associated infections due to biofilm-producing methicillin-resistant Staphylococcus aureus (MRSA) have been recently associated with the failure of antibiotic treatment and decolonization measures. The goal of our study was to evaluate
Blessing, Brigitte, Günther, Frank, Mutters, Nico T., Tacconelli, Evelina   +3 more
core   +2 more sources

The antimicrobial polymer PHMB enters cells and selectively condenses bacterial chromosomes [PDF]

, 2016
To combat infection and antimicrobial resistance, it is helpful to elucidate drug mechanism(s) of action. Here we examined how the widely used antimicrobial polyhexamethylene biguanide (PHMB) kills bacteria selectively over host cells.
A Gentile, B Spellberg, CE Barry, CR Messick, DJ Dwyer, EE Creppy, EF Palermo, FW O’Grady, G Muller, G Muller, G Rusciano, GS Gordon, J Portugal, JD McCool, JM Boberek, JP Armitage, L Good, LP O’Malley, M Mondhe, MA Kohanski, MJ Allen, MJ Allen, MJ Allen, N Nekhotiaeva, Nakashima, P Broxton, P Broxton, P Broxton, P Erbacher, P Gilbert, R de Vries, R Dryselius, R Firdessa, R Spurio, RF Murphy, S Amoils, S Goh, S Wessels, T Ikeda, T Ikeda, T Kornberg, VB Teif   +41 more
core   +3 more sources

Polyhexanide - safety and efficacy as an antiseptic.

Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke, 2017
BACKGROUND Polyhexamethylene biguanide hydrochloride/polyhexanide/polyaminopropyl biguanide (PHMB) is used as a disinfectant and antiseptic. This article discusses the use of the substance as an antiseptic. We summarise published data on its antimicrobial effect in vitro and its clinical effect and safety when used on skin, wounds and mucosa.MATERIAL ...
Hilde, Fjeld, Egil, Lingaas
openaire   +2 more sources

Meta-analysis and systematic review of skin graft donor-site dressings with future guidelines. [PDF]

, 2018
Background: Many types of split-thickness skin graft (STSG) donor-site dressings are available with little consensus from the literature on the optimal dressing type. The purpose of this systematic review was to analyze the most recent outcomes regarding
Alwaal, Assadian, Baser, Begg, Blount, Brown, Brölmann, Cheesborough, Chung, Cigna, Demirtas, Dickersin, Druery, Fearmonti, Feldman, Fernandes de Carvalho, Ferreira, Ghieh, Goertz, Haith, Hasatsri, Hassanpour, Healy, Iwuagwu, Jadad, Junker, Kaiser, Konieczynska, Konieczynska, Konieczynska, Lairet, Liu, Lohsiriwat, Massand, McCartan, Metelmann, Moher, Muangman, Petruzzelli, Polfer, Potocká, Quinn, Rakel, Ratner, Salehi, Selig, Serino, Singh, Siritientong, Soltan Dallal, Tan, Tanaka, Vaghardoost, Vejdan, Villa-Camacho, Voineskos, Wiechula, Wisely, Zidan   +58 more
core   +1 more source