Results 131 to 140 of about 23,262 (184)

Revisiting the PCR‐Based Molecular Approaches for Mycotoxigenic Fusarium Species Detection and Quantification in Wheat

open access: yesComprehensive Reviews in Food Science and Food Safety, Volume 25, Issue 5, September 2026.
ABSTRACT Fusarium species cause yield losses in wheat production through fusarium head blight (FHB) and the associated contamination of regulated mycotoxins, such as trichothecenes and zearalenone. Despite the widespread use of PCR‐based molecular approaches for Fusarium detection, quantification, and chemotyping, most primers were developed prior to ...
Kavitha Vijeandran   +9 more
wiley   +1 more source

ω‐Hydroxyacid Dehydrogenases From Clostridium viride: Iron‐Containing Biocatalysts With Biotechnological Potential

open access: yesChemBioChem, Volume 27, Issue 16, 27 August 2026.
ω‐Hydroxy and ω‐oxo acids are precursors to lactones, polyesters, and nylon‐6, yet selective interconverting enzymes remain scarce. Clostridium viride supplies two iron alcohol dehydrogenases: Cvir‐Hbd2, restricted to C4, and the genomic singleton Cvir‐Hvd, spanning C5–C12 substrates.
Tarik Begic   +7 more
wiley   +1 more source

Medicinal and Crop Protection Chemistry: Breaking Barriers, Building Synergies

open access: yesChemMedChem, Volume 21, Issue 16, 27 August 2026.
A unified view of medicinal and crop protection chemistry reveals shared scientific progress, common challenges, and new opportunities for cross‐disciplinary collaboration. Bridging expertise across both fields could accelerate innovation and actively encourage more sustainable solutions.
Giulia Cazzaniga   +5 more
wiley   +1 more source

Traffic Control in Modular Polyketide Synthases

open access: yesACS Central Science, 2016
Kara Finzel, Michael D. Burkart
doaj   +1 more source

A CRISPR-Cas9 system for knock-out and knock-in of high molecular weight DNA enables module-swapping of the pikromycin synthase in its native host

open access: yesMicrobial Cell Factories
Background Engineers seeking to generate natural product analogs through altering modular polyketide synthases (PKSs) face significant challenges when genomically editing large stretches of DNA.
Zhe-Chong Wang   +3 more
doaj   +1 more source

Engineered polyketide synthases for production of commodity and specialty chemicals [PDF]

open access: yes, 2018
Engineered modular polyketide synthases (PKSs) have the potential to be an extraordinarily effective retrosynthesis platform. Native PKSs assemble and tailor simple, readily available cellular acyl-CoAs into large, complex, chiral molecules.
Keasling, Jay
core  

Engineering Hybrid Pikromycin-Rapamycin Polyketide Synthases for Customized Antibiotic Biosynthesis

open access: yes
Engineering hybrid polyketide synthases (PKSs) offers a powerful route for producing novel bioactive molecules, but achieving functional module exchange remains challenging. Here, we report the creation of two series of hybrid PKSs combining modules from
Stegall, Hayden
core   +1 more source

A Noncanonical Reducing-Domain Architecture Defines a New Class of Modular Polyketide Synthases

open access: yes
Colibactin is a microbiome-derived genotoxin that damages the genomes of intestinal epithelial cells and has been linked to colorectal cancer. Its biosynthesis is encoded by a large gene cluster ( pks /
Jongseok Park   +8 more
core   +1 more source

In silicio expression analysis of PKS genes isolated from Cannabis sativa L.

open access: yesGenetics and Molecular Biology, 2010
Cannabinoids, flavonoids, and stilbenoids have been identified in the annual dioecious plant Cannabis sativa L. Of these, the cannabinoids are the best known group of this plant's natural products.
Isvett J. Flores-Sanchez   +2 more
doaj  

Polyketide Synthases

open access: yesActa Scientific Microbiology, 2019
openaire   +1 more source

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