Poly(lactic acid) (PLA) and poly(glycolic acid) (PGA) are extensively studied biodegradable polymers. However, the degradation behavior of their copolymer, poly(lactic-co-glycolic acid) (PLGA), in marine environments has not yet been confirmed. In this study, the changes in macroscopic and microscopic morphology, thermal properties, aggregation, and ...
Zeyu Chen +6 more
openaire +4 more sources
Supra and subgingival application of antiseptics or antibiotics during periodontal therapy
Abstract Periodontal diseases (gingivitis and periodontitis) are characterized by inflammatory processes which arise as a result of disruption of the balance in the oral ecosystem. According to the current S3 level clinical practice guidelines, therapy of patients with periodontitis involves a stepwise approach that includes the control of the patient ...
Elena Figuero +5 more
wiley +1 more source
A Systematic Experimental and Computational Analysis of Commercially Available Aliphatic Polyesters
Aliphatic polyesters, such as polylactic acid (PLA), polyglycolic acid (PGA), and their copolymer polylactic-co-glycolic acid (PLGA) have become an established choice in the biomedical field in a wide range of applications, from nanoparticles for local ...
Tommaso Casalini +7 more
doaj +1 more source
Stimulation of bone growth with thrombin peptide derivatives [PDF]
Disclosed is a method of stimulating bone growth at a site in a subject in need of osteoinduction. The method comprises the step of administering a therapeutically effective amount of an agonist of the non-proteolytically activated thrombin receptor to ...
Carney, Darrell H. +4 more
core +2 more sources
Production, by co-grinding in a media mill, of porous biodegradable polylactic acid-apatite composite materials for bone tissue engineering [PDF]
This paper presents the results of a study of the production of porous biodegradable composite materials by co-grinding, followed by scaffolding. Dry powders of polylactic acid and nanocrystalline carbonated apatite, analogous to bone mineral were co ...
Combes, Christèle +6 more
core +2 more sources
Polymer- and Hybrid-Based Biomaterials for Interstitial, Connective, Vascular, Nerve, Visceral and Musculoskeletal Tissue Engineering [PDF]
In this review, materials based on polymers and hybrids possessing both organic and inorganic contents for repairing or facilitating cell growth in tissue engineering are discussed.
Abalymov, Anatolii +2 more
core +1 more source
Background: Among treatment modalities, grafting of biomaterials/bone substitutes has been used with varying success to accomplish the reconstruction of the lost periodontal attachment apparatus.
Motilal R Jangid +3 more
doaj +1 more source
Electrospun collagen-based nanofibres: A sustainable material for improved antibiotic utilisation in tissue engineering applications [PDF]
For the creation of scaffolds in tissue engineering applications, it is essential to control the physical morphology of fibres and to choose compositions which do not disturb normal physiological function. Collagen, the most abundant protein in the human
Ahmed +52 more
core +3 more sources
本研究は, rhBMP-2を, 担体にポリ乳酸グリコール酸共重合体/ゼラチンスポンジ複合体 (PGS) を用いてルートプレーニングした根面に移植した場合のセメント質, 歯根膜, 歯槽骨の誘導再生, および歯根吸収と骨性癒着の発現の危険性を検討する目的で, イヌに開窓状歯槽骨欠損 (5×5mm) を作製し骨欠損周囲のセメント質と歯根膜に電気メスを用いて損傷を与えた後, 対照群には担体のみを移植し, 実験群にはrhBMP-2を配合比率0.4μg/mm3で移植し, 病理組織学的観察と組織学的計測を行つた。観察期間は13~16週とした。対照群では術後4週に2部位に炎症を伴う腫脹が生じたが, 実験群は観察期間終了時まで良好であった。骨の再生率は, 実験群約97%, 対照群約81%で統計学的有意差 ...
Tomoomi Odajima +2 more
openaire +2 more sources
Processing of biocompatible materials on a polymer basis by a lowtemperature plasma at atmospheric pressure [PDF]
In the present work we investigated the effect of low-temperature treatment in the flow of argon on composite materials based on Poly-L-lactide/Hydroxyapatite (PL/HA) in the ratio of 70/30 and hydroxyapatite and lactide and glycolide copolymer (SLG-HA ...
Imöhl, Matthias +3 more
core +1 more source

