Viability and Adhesion of Periodontal Ligament Fibroblasts on a Hydroxyapatite Scaffold Combined with Collagen, Polylactic Acid–Polyglycolic Acid Copolymer and Platelet-Rich Fibrin: A Preclinical Pilot Study [PDF]
Background: Conventional periodontal therapy relies on bone regeneration strategies utilizing scaffolds made of diverse materials, among which collagen, to promote cell adhesion and growth.
Leonor C. Espitia-Quiroz +7 more
doaj +6 more sources
Clinical and Radiographic Evaluation of Nanohydroxyapatite Powder in Combination with Polylactic Acid/Polyglycolic Acid Copolymer as Bone Replacement Graft in the Surgical Treatment of Intrabony Periodontal Defects: A Retrospective Case Series Study. [PDF]
The aim of this retrospective case series was to evaluate the clinical efficacy of nanohydroxyapatite powder (NHA) in combination with polylactic acid/polyglycolic acid copolymer (PLGA) as a bone replacement graft in the surgical treatment of intrabony periodontal defects.
Verardi S, Lombardi T, Stacchi C.
europepmc +6 more sources
The study was designed to compare the extent of bacterial colonisation on the surface of Polylactic acid/Polyglycolic acid copolymer and expanded Polytetrafluoroethylene based Guided tissue regeneration (GTR) membrane in an in vitro model by spot ...
Shubham Sareen +3 more
doaj +2 more sources
Improvement of intertrochanteric bone quality in osteoporotic female rats after injection of polylactic acid-polyglycolic acid copolymer/collagen type I microspheres combined with bone mesenchymal stem cells. [PDF]
Osteoporosis mainly involves cancellous bone, and the spine and hip, with their relatively high cancellous bone to cortical bone ratio, are severely affected. Studies of bone mesenchymal stem cells (BMSCs) from osteoporotic patients and animal models have revealed that osteoporosis is often associated with reduction of BMSCs' proliferation and ...
Yu Z +6 more
europepmc +4 more sources
Cytotoxicity of PLGA-zinc oxide nanocomposite on human gingival fibroblasts [PDF]
Background. Polylactic-co-glycolic acid and zinc oxide (PLGA-ZnO) nanocomposite has been investigated for its antibacterial properties, which could be beneficial for adding to wound dressings after periodontal surgery.
Asieh Mozaffari +3 more
doaj +1 more source
A review study on the application of polymeric-based nanoparticles as a novel approach for enhancing the stability of albumins [PDF]
Albumin is a liver synthesized protein and the most abundant non-glycosylated plasma protein with a molecular weight of 66 kDa and 585 amino acids. It works as a preservative to maintain plasma volume, osmotic blood pressure, and microvascular integrity.
Tahereh Zadeh Mehrizi +3 more
doaj +1 more source
Simvastatin embedded into poly(lactic-co-glycolic acid) (PLGA)-based scaffolds can stimulate bone regeneration in preclinical models. However, the ideal pharmacological dose has not been evaluated.
Eduarda Blasi Magini +7 more
doaj +1 more source
Polylactic/polyglycolic acid copolymer is a good carrier for BMP-2 on bone regeneration?
The aim of this work was to evaluate the role of polylactic /polyglycolic acid copolymer as carrier for BMP-2 on bone regeneration in rat calvarium. Forty five adult male rats underwent 5-mm critical defects in bone calvaria to be divided into three ...
Alexandre Ladeira Veloso dos Anjos +7 more
doaj +3 more sources
Preimplantation filling of tooth socket with β-tricalcium phosphate/polylactic-polyglycolic acid (β-TCP/PLGA) root analogue: clinical and histological analysis in a patient [PDF]
Introduction. Bone resorption is a physiological process after tooth extraction. The use of bone substitutes to fill the tooth socket is suggested to prevent bone resorption and establish good bone architecture for implant placement.
Koković Vladimir, Todorović Ljubomir
doaj +1 more source
In Vitro Comparative Study of Oxygen Plasma Treated Poly(Lactic–Co–Glycolic) (PLGA) Membranes and Supported Nanostructured Oxides for Guided Bone Regeneration Processes [PDF]
Background: The use of physical barriers to prevent the invasion of gingival and connective tissue cells into bone cavities during the healing process is called guided bone regeneration.
Barranco Quero, Ángel +6 more
core +2 more sources

