Viability and Adhesion of Periodontal Ligament Fibroblasts on a Hydroxyapatite Scaffold Combined with Collagen, Polylactic Acid–Polyglycolic Acid Copolymer and Platelet-Rich Fibrin: A Preclinical Pilot Study [PDF]
Dentistry Journal, 2022 Background: Conventional periodontal therapy relies on bone regeneration strategies utilizing scaffolds made of diverse materials, among which collagen, to promote cell adhesion and growth.
Leonor C. Espitia-Quiroz +7 more
doaj +5 more sources
Polylactic/polyglycolic acid copolymer is a good carrier for BMP-2 on bone regeneration? [PDF]
Bioscience Journal, 2017 The aim of this work was to evaluate the role of polylactic /polyglycolic acid copolymer as carrier for BMP-2 on bone regeneration in rat calvarium. Forty five adult male rats underwent 5-mm critical defects in bone calvaria to be divided into three ...
Alexandre Ladeira Veloso dos Anjos +7 more
doaj +8 more sources
Clinical and Radiographic Evaluation of Nanohydroxyapatite Powder in Combination With Polylactic Acid/Polyglycolic Acid Copolymer as Bone Replacement Graft in the Surgical Treatment of Intrabony Periodontal Defects: A Retrospective Case Series Study [PDF]
Materials, 2020 The aim of this retrospective case series was to evaluate the clinical efficacy of nanohydroxyapatite powder (NHA) in combination with polylactic acid/polyglycolic acid copolymer (PLGA) as a bone replacement graft in the surgical treatment of intrabony ...
Teresa Lombardi, Claudio Stacchi
exaly +3 more sources
Journal of Clinical Sciences, 2017 Background: Among treatment modalities, grafting of biomaterials/bone substitutes has been used with varying success to accomplish the reconstruction of the lost periodontal attachment apparatus.
Motilal R Jangid +3 more
doaj +4 more sources
Preimplantation filling of tooth socket with β-tricalcium phosphate/polylactic-polyglycolic acid (β-TCP/PLGA) root analogue: clinical and histological analysis in a patient [PDF]
Vojnosanitetski Pregled, 2011 Introduction. Bone resorption is a physiological process after tooth extraction. The use of bone substitutes to fill the tooth socket is suggested to prevent bone resorption and establish good bone architecture for implant placement.
Koković Vladimir, Todorović Ljubomir
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In vitro Comparative Evaluation of Polylactic Acid/Polyglycolic Acid Copolymer and Expanded Polytetrafluoroethylene Based Guided Tissue Regeneration Membrane for Bacterial Colonisation [PDF]
Journal of Pure and Applied Microbiology, 2023 The study was designed to compare the extent of bacterial colonisation on the surface of Polylactic acid/Polyglycolic acid copolymer and expanded Polytetrafluoroethylene based Guided tissue regeneration (GTR) membrane in an in vitro model by spot ...
Shubham Sareen +3 more
doaj +2 more sources
Cytotoxicity of PLGA-zinc oxide nanocomposite on human gingival fibroblasts [PDF]
Journal of Advanced Periodontology and Implant Dentistry, 2023 Background. Polylactic-co-glycolic acid and zinc oxide (PLGA-ZnO) nanocomposite has been investigated for its antibacterial properties, which could be beneficial for adding to wound dressings after periodontal surgery.
Asieh Mozaffari +3 more
doaj +1 more source
A review study on the application of polymeric-based nanoparticles as a novel approach for enhancing the stability of albumins [PDF]
Nanomedicine Journal, 2022 Albumin is a liver synthesized protein and the most abundant non-glycosylated plasma protein with a molecular weight of 66 kDa and 585 amino acids. It works as a preservative to maintain plasma volume, osmotic blood pressure, and microvascular integrity.
Tahereh Zadeh Mehrizi +3 more
doaj +1 more source
Applied Sciences, 2022 Simvastatin embedded into poly(lactic-co-glycolic acid) (PLGA)-based scaffolds can stimulate bone regeneration in preclinical models. However, the ideal pharmacological dose has not been evaluated.
Eduarda Blasi Magini +7 more
doaj +1 more source
A Systematic Experimental and Computational Analysis of Commercially Available Aliphatic Polyesters
Applied Sciences, 2019 Aliphatic polyesters, such as polylactic acid (PLA), polyglycolic acid (PGA), and their copolymer polylactic-co-glycolic acid (PLGA) have become an established choice in the biomedical field in a wide range of applications, from nanoparticles for local ...
Tommaso Casalini +7 more
doaj +1 more source