Results 31 to 40 of about 27,252 (197)

Influence of water on localized and delocalized molecular mobility of cellulose [PDF]

open access: yes, 2007
The influence of hydration on cellulose molecular mobility is investigated by two dielectric methods at different molecular scale. The mobility of side groups, assigned to c mode, for dried cellulose increases.
Boudet, Alain-Michel   +4 more
core   +2 more sources

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

open access: yesMolecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos   +6 more
wiley   +1 more source

Fragility of a thermoplastic polymer. Influence of main chain rigidity in polycarbonate [PDF]

open access: yes, 2005
We present new data on a vitreous polycarbonate (PC) and its fragility index. Measurements have been performed by means of differential scanning calorimetry (DSC).
Bernès, Alain   +4 more
core   +2 more sources

Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer

open access: yesMolecular Oncology, EarlyView.
COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann   +61 more
wiley   +1 more source

Dielectric relaxations and ferroelectric behaviour of even–odd polyamide PA 6,9 [PDF]

open access: yes, 2010
Thermo Stimulated Current (TSC) combined with Dynamic Dielectric Spectroscopy (DDS) have been applied to the investigation of dielectric relaxation modes of an even–odd Polyamide PA 6,9.
Bernès, Alain   +10 more
core   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch   +13 more
wiley   +1 more source

Dual PI3K/AKT and CDK4/6 inhibition reveals selective sensitivity in an SHH medulloblastoma stem cell model

open access: yesMolecular Oncology, EarlyView.
Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute   +4 more
wiley   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

Etude numérique de la coextrusion de polyester : Effet de la régulation thermique et de la géométrie de la filière sur la stabilisation des instabilités interfaciales [PDF]

open access: yes, 2007
http://hdl.handle.net/2042/16637International audienceLa fabrication d'un film multicouche peut être réalisée de manière économique par l'utilisation de la technique de coextrusion.
Agassant, Jean-François   +4 more
core   +1 more source

Nanotexture influence of BaTiO3 particles on piezoelectric behaviour of PA 11/BaTiO3 nanocomposites [PDF]

open access: yes, 2010
The piezoelectric activity of a hybrid ferroelectric nanocomposite, i.e. polyamide 11/barium titanate (BT), has been investigated for different loadings of BT particles.
Capsal, J.-F.   +5 more
core   +1 more source

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