Results 51 to 60 of about 27,114 (247)

The role of histone modifications in transcription regulation upon DNA damage

FEBS Letters, EarlyView.
This review discusses the critical role of histone modifications in regulating gene expression during the DNA damage response (DDR). By modulating chromatin structure and recruiting repair factors, these post‐translational modifications fine‐tune transcriptional programmes to maintain genomic stability.
Angelina Job Kolady, Siyao Wang
wiley   +1 more source

FOTOPOLIMERI PE BAZĂ DE IZOTIOCIANATOCARBAZOLILMETACRILAŢI

Studia Universitatis Moldaviae: Stiinte reale si ale naturii, 2007
Dans la présente publication on propose des résultats visant le domaine de la synthèse des monomères et des polymères carbasoliques, contenant le substituent NCS, qui va activiser les propriétés phototermoplastiques des matériaux à la base de ces ...
USM ADMIN
doaj  

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

FEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson, Mackenzie K Herroon, Shane Mecca, Laimar C Garmo, Jacob Lindquist, Shrila Rajendran, Steve M. Patrick, Izabela Podgorski   +7 more
wiley   +1 more source

Des matières qui travaillent : Une leçon pour l’anthropologie (Note de recherche) [PDF]

, 2006
De nouvelles matières font désormais concurrence aux artefacts et aux fonctions selon des modes appelés à déstabiliser notre façon d’envisager la nature du monde social et culturel que nous habitons.
Küchler, Susanne
core   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

FEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee, Dimitrios Bekiari, Sofia Doello, Karl Forchhammer   +3 more
wiley   +1 more source

A Multi-Omics Analysis Suggests Links Between the Differentiated Surface Metabolome and Epiphytic Microbiota Along the Thallus of a Mediterranean Seaweed Holobiont

Frontiers in Microbiology, 2020
Marine macroalgae constitute an important living resource in marine ecosystems and complex ecological interactions occur at their surfaces with microbial communities.
Benoît Paix, Nathan Carriot, Raphaëlle Barry-Martinet, Stéphane Greff, Benjamin Misson, Jean-François Briand, Gérald Culioli   +6 more
doaj   +1 more source

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

Molecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker, Keren Zohar, Martin Böttcher, Thomas Wartmann, Henry Freudenstein, Maximilian Doelling, Mihailo Andric, Wenjie Shi, Or Kakhlon, Katrin Hippe, Beatrix Jahnke, Dimitrios Mougiakakos, Franziska Baenke, Daniel Stange, Roland S. Croner, Michal Linial, Ulf D. Kahlert   +16 more
wiley   +1 more source

Les mélanges de polymères incompatibles Incompatible Polymer Mixtures

Oil & Gas Science and Technology, 2006
Les mélanges de polymères thermoplastiques font actuellement l'objet d'un effort considérable de recherche et de développement. Cette synthèse bibliographique concerne principalement les mélanges mécaniques de polymères incompatibles à l'état fondu. Ceux-
Serpe G., Jarrin J., Dawans F.
doaj   +1 more source

Tailoring Biodegradability of Poly(Butylene Succinate)/Poly(Lactic Acid) Blends With a Deep Eutectic Solvent

Frontiers in Materials, 2020
Biodegradable polymers concern an important topic for innovation in materials, as they are supposed to contribute to the reduction in the amount of waste materials, which lead to microplastics with similar properties as conventional polymer materials ...
Emma Delamarche, Emma Delamarche, Agnès Mattlet, Sébastien Livi, Jean-François Gérard, Rémy Bayard, Valérie Massardier   +6 more
doaj   +1 more source

Technique d’imagerie par rayons X en contraste de phase pour du contrôle de matériaux composite

e-Journal of Nondestructive Testing, 2023
Le contraste de phase en imagerie par rayons X permet de voir des détails de structures dans les matériaux peu absorbants. Plusieurs techniques existent mais l’interférométrie à décalage multilatérale (IDML) permet une mesure simultanée des gradients de
Laureen Guitard, Adrien Stolidi, Amélie Jarnac, Jérôme Primot   +3 more
doaj   +1 more source