Results 21 to 30 of about 911,913 (268)

Fast Humidity Sensors for Harsh Environment

Proceedings, 2018
With the application of a recently developed deposition method called initiated chemical vapor deposition (iCVD), remarkably fast responsive hydrogel thin films in the order of a few hundred nanometers were created.
Anton Buchberger, Anna Maria Coclite, Alexander Bergmann   +2 more
doaj   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

FEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson, Mackenzie K Herroon, Shane Mecca, Laimar C Garmo, Jacob Lindquist, Shrila Rajendran, Steve M. Patrick, Izabela Podgorski   +7 more
wiley   +1 more source

Influence of injection volume rate–driven temperature evolution on the molecular and mechanical properties of PA6.6 in injection molding

Polymer Testing
This study investigates the influence of injection volume rate (IVR) on local temperature development in a narrow slit and its effects on the mechanical and molecular properties of unfilled polyamide 6.6 (PA 6.6).
David Zidar, Zahra Shahroodi, Roman Staudigl, Walter Friesenbichler, Thomas Lucyshyn, Clemens Holzer   +5 more
doaj   +1 more source

Evaluation of Bisphenol-A Release from Vacuum formed Retainers after Immersion in Distilled Water using High Performance Liquid Chromatography: A Randomised Clinical Trial [PDF]

Journal of Clinical and Diagnostic Research
Introduction: With the increasing demand for aesthetics, the popularity of Vacuum-formed Retainers (VFRs) has been on the rise. Bisphenol-A (BPA) is added to the polymers to make them clear and tough. BPA is identified as an endocrine disruptor linked to
Lalita Girish Nanjannawar, Piyush Sanjay Patil, Simran Neeraj Budhraja, Sangamesh Gurunath Fulari, Amol Sarjerao Shirkande, Ankita Manik Mohite   +5 more
doaj   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

FEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee, Dimitrios Bekiari, Sofia Doello, Karl Forchhammer   +3 more
wiley   +1 more source

Simultaneous delayed fluorescence and phosphorescence in organic luminescent material employing multiple excited states

Light: Science & Applications
Triplet dynamics play a key role in room temperature phosphorescence (RTP) and thermally activated delayed fluorescence (TADF). In this work, we report a model emitter with three emission components: prompt fluorescence (PF) in nanoseconds, delayed ...
Dehai Dou, Wenlan Liu, Xin Zhou, Qiqi Yang, Xiao Tan, Naz Ugur, Chongyao Li, Charusheela Ramanan, Xiaomin Liu, Gert-Jan A. H. Wetzelaer, Denis Andrienko, Martin Baumgarten, Paul W. M. Blom, Yungui Li   +13 more
doaj   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway

Molecular Oncology, EarlyView.
Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed, Kerstin Huebner, Katharina Erlenbach‐Wuensch, Chuanpit Hampel, Daniela Thalheim, Adriana Vial‐Roehe, Bodee Nutho, Susanne Merkel, Arndt Hartmann, Pithi Chanvorachote, Regine Schneider‐Stock   +10 more
wiley   +1 more source

Segmented multiblock polyolefin compatibilizers from non-living metathesis chain-shuffling

Nature Communications
The mechanical properties of mixed plastics can be enhanced by block copolymer compatibilizer additives. Here we report a series of semi-crystalline/semi-crystalline linear multiblock copolymers of LLDPE and PP, the two most abundant plastics, from a non-
Abhishek Banerjee, Navin Kafle, Walter G. Romano, Harsh Pandya, Shin Horiuchi, Aarushi Srivastava, Fardin Khabaz, Mark D. Foster, Toshikazu Miyoshi, James M. Eagan   +9 more
doaj   +1 more source