Results 31 to 40 of about 646,069 (216)
Vapor sorption in binary polymer brushes: The effect of the polymer–polymer interface [PDF]
, 2021 Polymer brushes attract vapors that are good solvents for polymers. This is useful in sensing and other technologies that rely on concentrating vapors for optimal performance.
Ritsema van Eck, Guido C. +6 more
core +1 more source
Molecular Oncology, EarlyView.Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source
COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells
Molecular Oncology, EarlyView.This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos +6 more
wiley +1 more source
Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer
Molecular Oncology, EarlyView.COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann +61 more
wiley +1 more source
Molecular Oncology, EarlyView.Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch +13 more
wiley +1 more source
Multiscale Implications of Stress-Induced Ionic Polymer Transducer Sensing [PDF]
, 2013 Ionic Polymer Transducers (IPTs) can act as both actuators and sensors. As actuators, the energy density values are much better than PZT or PVDF materials.
Zangrilli, Ursula
core
Molecular Oncology, EarlyView.Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute +4 more
wiley +1 more source
Nanoscale fillers. Fillers for high oxygen permeability polymer films [PDF]
, 2007 A wide range of polymer film products are available with varying degrees of permeability to a variety of gases, from oxygen to water to aromatic species.
Fay, Jonathan D B, Fay, Jonathan D. B.
core
Flexible polymer-induced condensation and bundle formation of DNA and F-actin filaments
, 2001 A simple semi-empirical theory is developed for the ionic strength dependence of the flexible polymer-induced condensation of semiflexible polyelectrolytes such as DNA and F-actin filaments.
Vries, R., de +2 more
core +1 more source
Thermal-Mechanical Properties of Polyurethane-Clay Shape Memory Polymer Nanocomposites [PDF]
, 2010 Shape memory nanocomposites of polyurethane (PU)-clay were fabricated by melt mixing of PU and nano-clay. Based on nano-indentation and microhardness tests, the strength of the nanocomposites increased dramatically as a function of clay content, which is
Kraft, Arno, +21 more
core +1 more source