Results 51 to 60 of about 1,860,269 (264)

PANoptosis in the pathogenesis of myelodysplastic syndromes

open access: yesMolecular Oncology, EarlyView.
PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla   +4 more
wiley   +1 more source

Ionic and nonionic polymer gels. [PDF]

open access: yes, 2008
Polymer Science and EngineeringDoctor of Philosophy (Ph.D.
McCoy, Jessica L.
core   +1 more source

Research Progress on Polymer-based Radiative Cooling Materials

open access: yesLiang you shipin ke-ji
In the process of grain storage, the use of low-temperature grain storage technology can effectively reduce grain losses during storage and ensure grain quality, which is of great significance for maintaining a stable grain supply.
GUO Yu   +7 more
doaj   +1 more source

NAPRT loss promotes lung tumor initiation and growth through AKT signaling independently of NAD+ biosynthesis

open access: yesMolecular Oncology, EarlyView.
Loss of NAPRT promotes lung tumor initiation and growth through a noncanonical mechanism, independent of its role in NAD+ biosynthesis. Mechanistically, NAPRT depletion activates the mTORC2‐driven AKT/β‐catenin signaling axis to enhance clonogenic and invasive phenotypes. Furthermore, lung‐specific Naprt deletion significantly increases tumor burden in
Myung Joon Oh   +11 more
wiley   +1 more source

PyGAMD: Python graphics processing unit‐accelerated molecular dynamics software

open access: yesMaterials Genome Engineering Advances
PyGAMD (Python GPU‐accelerated molecular dynamics software) is a molecular simulation platform developed from scratch. It is designed for soft matter, especially for polymer by integrating coarse‐grained/multi‐scale models, methods, and force fields.
Jialei Xu   +6 more
doaj   +1 more source

Hydrogel technology increases resilience of Inga edulis seedlings under drought conditions [PDF]

open access: yesBrazilian Journal of Biology
Technologies that can mitigate the stressful effect of water deficit and assist in seedling recovery are necessary. This study aimed to evaluate the effect of hydrogel doses on mitigating water deficit stress and the recovery of Inga edulis Mart ...
J. M. Silverio   +5 more
doaj   +1 more source

Paclitaxel induces NM2‐dependent cellular contraction through GEF‐H1 dissociation from microtubules and RhoA/ROCK activation in cancer cells

open access: yesMolecular Oncology, EarlyView.
Taxanes are widely used chemotherapeutics whose effects on cellular mechanics remain poorly understood. We show that paclitaxel induces rapid cellular contraction by promoting GEF‐H1 dissociation from microtubules and non‐muscle myosin II activation through RhoA/ROCK.
Gloria Asensio‐Juárez   +5 more
wiley   +1 more source

Hole-transporting host-polymer series consisting of triphenylamine basic structures for phosphorescent polymer light-emitting diodes

open access: yes, 2022
S.3417-3430A series of novel styrene derived monomers with triphenylamine-based units, and their polymers have been synthesized and compared with the well-known structure of polymer of N,N'-bis(3-methylphenyl)-N,N'-diphenylbenzidine with respect to their
Debeaux, M.   +7 more
core   +1 more source

Polymer Delivery Systems for Long-Acting Antiretroviral Drugs

open access: yesPharmaceutics
The success of long-acting (LA) drug delivery systems (DDSs) is linked to their biocompatible polymers. These are used for extended therapeutic release. For treatment or prevention of human immune deficiency virus type one (HIV-1) infection, LA DDSs hold
Mohammad Ullah Nayan   +7 more
doaj   +1 more source

Home - About - Disclaimer - Privacy