Results 61 to 70 of about 2,350,876 (296)

Shape Fluctuations of a Droplet Containing a Polymer

open access: yes, 1995
We consider the problem of an ideal polymer confined in a droplet. When the droplet radius is smaller than the (unconfined) polymer radius of gyration, the polymer entropy will depend on the droplet shape.
Goulian, M., Milner, S. T.
core   +2 more sources

Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer

open access: yesMolecular Oncology, EarlyView.
COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann   +61 more
wiley   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch   +13 more
wiley   +1 more source

Microplastic Pollution in Tropical River: Fourier Transform Infrared Spectroscopy-Based Characterization of Abundance and Polymer Composition in Water and Sediments from Filobobos River, Mexico

open access: yesHydrology
Veracruz is a megadiverse state facing great water resource management challenges. The contamination of water bodies with external materials of anthropogenic origin stands out, including those derived from plastic products, which are deemed ubiquitous ...
Gleybis Hernández-Morales   +6 more
doaj   +1 more source

Fluctuations in Polymer Translocation

open access: yes, 2010
We investigate a model of chaperone-assisted polymer translocation through a nanopore in a membrane. Translocation is driven by irreversible random sequential absorption of chaperone proteins that bind to the polymer on one side of the membrane.
Abramowitz M   +21 more
core   +3 more sources

Dual PI3K/AKT and CDK4/6 inhibition reveals selective sensitivity in an SHH medulloblastoma stem cell model

open access: yesMolecular Oncology, EarlyView.
Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute   +4 more
wiley   +1 more source

Polymeric and Crystalline Materials for Effective and Sustainable CO2 Capture

open access: yesAppliedChem
Carbon dioxide (CO2) is recognized as the primary cause of global warming due to its greenhouse potential. It plays a significant role in contributing to the emissions arising from a variety of anthropogenic activities, such as energy production ...
David Gendron, Maria Zakharova
doaj   +1 more source

Ground state properties of ferromagnetic metal/conjugated polymer interfaces

open access: yes, 2002
We theoretically investigate the ground state properties of ferromagnetic metal/conjugated polymer interfaces. The work is partially motivated by recent experiments in which injection of spin polarized electrons from ferromagnetic contacts into thin ...
A. R. Bishop   +26 more
core   +1 more source

STAR POLYMERS [PDF]

open access: yesCondensed Matter Physics, 2002
It is our great pleasure to present a collection of papers devoted to theoretical, numerical, and experimental studies in the field of star polymers. Since its introduction in the early 80-ies, this field has attracted increasing interest and has become an important part of contemporary polymer physics.
von Ferber, Ch., Holovatch, Yu.
openaire   +3 more sources

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

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