Results 71 to 80 of about 3,997,963 (398)

Hydrogels for localized chemotherapy of liver cancer: a possible strategy for improved and safe liver cancer treatment

open access: yesDrug Delivery, 2022
The systemic drug has historically been preferred for the treatment of the majority of pathological conditions, particularly liver cancer. Indeed, this mode of treatment is associated with adverse reactions, toxicity, off-target accumulation, and rapid ...
Jianyong Ma   +6 more
doaj   +1 more source

Cellular liquid biopsy provides unique chances for disease monitoring, preclinical model generation and therapy adjustment in rare salivary gland cancer patients

open access: yesMolecular Oncology, EarlyView.
We quantified and cultured circulating tumor cells (CTCs) of 62 patients with various cancer types and generated CTC‐derived tumoroid models from two salivary gland cancer patients. Cellular liquid biopsy‐derived information enabled molecular genetic assessment of systemic disease heterogeneity and functional testing for therapy selection in both ...
Nataša Stojanović Gužvić   +31 more
wiley   +1 more source

Phenylboronic ester-modified polymeric nanoparticles for promoting TRP2 peptide antigen delivery in cancer immunotherapy

open access: yesDrug Delivery, 2022
The tremendous development of peptide-based cancer vaccine has attracted incremental interest as a powerful approach in cancer management, prevention and treatment.
Qiyan Wang   +7 more
doaj   +1 more source

Coil--globule transition of a polymer involved in excluded-volume interactions with macromolecules [PDF]

open access: yes, 2015
Polymers adopt extended coil and compact globule states according to the balance between entropy and interaction energies. The transition of a polymer between an extended coil state and compact globule state can be induced by changing thermodynamic force such as temperature to alter the energy/entropy balance.
arxiv   +1 more source

Effect of excluded volume interactions on the interfacial properties of colloid-polymer mixtures [PDF]

open access: yesJ. Chem. Phys. 128, 024904 (2008), 2007
We report a numerical study of equilibrium phase-diagrams and interfacial properties of bulk and confined colloid-polymer mixtures using grand canonical Monte Carlo simulations. Colloidal particles are treated as hard spheres, while the polymer chains are described as soft repulsive spheres.
arxiv   +1 more source

The PTTG1/VASP axis promotes oral squamous cell carcinoma metastasis by modulating focal adhesion and actin filaments

open access: yesMolecular Oncology, EarlyView.
VASP was found to be overexpressed in metastatic oral squamous cell carcinoma (OSCC) tissues. Notably, PTTG1‐ and VASP‐deficient OSCC cells demonstrated suppressed metastatic properties by disrupting the interaction between the cytoskeleton and focal adhesion (FAs) in the filopodia region.
Suyeon Park   +6 more
wiley   +1 more source

Frontiers in the Interaction of Chemically Reactive Species From Gaseous Plasma With Hydrophobic Polymers

open access: yesFrontiers in Physics, 2022
Surface functionalization of polymers by chemically reactive oxygen is a standard technique for increasing the surface energy of polymers. The technique, however, usually does not provide the desired surface finish of many polymers, including highly ...
Rok Zaplotnik, Miran Mozetič
doaj   +1 more source

Molecular recognition by van der Waals interaction between polymers with sequence-specific polarizabilities [PDF]

open access: yesJ. Chem. Phys. 142, 214904 (2015), 2015
We analyze van der Waals interactions between two rigid polymers with sequence-specific, anisotropic polarizabilities along the polymer backbones, so that the dipole moments fluctuate parallel to the polymer backbones. Assuming that each polymer has a quenched-in polarizability sequence which reflects, for example, the polynucleotide sequence of a ...
arxiv   +1 more source

Polymer Film-producing Methods And Devices Produced Therefrom [PDF]

open access: yes, 2013
Described herein are improved methods of forming polymer films, the polymer films formed thereby, and electronic devices formed form the polymer films.

core  

Cystatin A promotes the antitumor activity of T helper type 1 cells and dendritic cells in murine models of pancreatic cancer

open access: yesMolecular Oncology, EarlyView.
Pancreatic ductal adenocarcinoma (PDAC) is a disease with very poor prognosis due to therapeutic limitations. We investigated the antitumor effects of cystatin A (CSTA) in PDAC murine models. We are first to confirm that CSTA enhances T helper type 1‐mediated antitumor effects through promotion of dendritic cells and M1 macrophage activity. CSTA can be
Alessandro Nasti   +8 more
wiley   +1 more source

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