Results 41 to 50 of about 682,509 (290)

Combining Soft Polysilazanes with Melt-Shear Organization of Core–Shell Particles: On the Road to Polymer-Templated Porous Ceramics

Molecules, 2019
The preparation of ordered macroporous SiCN ceramics has attracted significant interest and is an attractive area for various applications, e.g., in the fields of catalysis, gas adsorption, or membranes.
Anna K. Boehm, Emanuel Ionescu, Marcus Koch, Markus Gallei   +3 more
doaj   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

Photo-responsive polymeric structures based on spiropyran [PDF]

, 2012
Spiropyrans are one of the most popular classes of photochromic compounds that change their optical and structural properties in response to external inputs such as light, protons and metal ions, making them ideal molecules for the fabrication of ...
Adelmann, Alonso, Anastasiadis, Angiolini, Bardavid, Bassetti, Beebe, Beiermann, Beiermann, Bell, Benito-Lopez, Benito-Lopez, Berkovic, Byrne, Byrne, Byrne, Byrne, Byrne, Cheng, Chung, Coleman, Coleman, Connal, Darwish, Dattilo, Davis, Delaire, Dong, Doron, Dürr, Fischer, Florea, Florea, Fries, Fries, Fries, Garcia, Guo, Higuchi, Hirshberg, Imai, Irie, Ivanov, Joseph, Kimura, Kobayashi, Kotharangannagari, Kwon, LaVan, Lee, Lee, Lee, Lee, Levy, Li, Lin, Lygeraki, Minkin, Natali, O'Bryan, Park, Park, Pennakalathil, Piech, Radu, Richter, Rosario, Rosario, Sakai, Samanta, Samoladas, Saragi, Satoh, Shiraishi, Shiraishi, Stauffer, Stitzel, Such, Sugiura, Suzuki, Tachibana, Wang, Zhao   +82 more
core   +2 more sources

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

FEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz, Mihály Mérey, Rebeka Vásárhelyi, Ramóna Pék, Victor Imburchia, László Henn, Adrián Kószó, Nicholas D. Lakin, Ivan Ahel, Sébastien Huet, Ágnes Czibula, Gyula Timinszky   +11 more
wiley   +1 more source

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

Molecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak, Karolina Pytlak, Sandra Jaworowska, Bogusz Kulawiak, Piotr Bednarczyk   +4 more
wiley   +1 more source

Types of Crosslinkers and Their Applications in Biomaterials and Biomembranes

Chemistry
Biomaterials and biomembranes play a crucial role in a variety of applications, particularly in the medical field due to their ability to mimic natural biological structures and functions.
Paolo Yammine, Ali El Safadi, Rima Kassab, Hanna El-Nakat, Pierre J. Obeid, Zeina Nasr, Tony Tannous, Nouha Sari-Chmayssem, Agapy Mansour, Ayman Chmayssem   +9 more
doaj   +1 more source

Quantum dot-labelled polymer beads by suspension polymerisation [PDF]

, 2003
CdSe quantum dots with polymerisable ligands have been incorporated into polystyrene beads, via a suspension polymerisation reaction, as a first step towards the optical encoding of solid supports for application in solid phase organic ...
Cummins, Siobhan S., Darcy, Dan, Dearden, Angela, Masala, Ombretta, O'Brien, Paul, Pickett, Nigel L., Ryley, Steve, Sutherland, Andrew J.   +7 more
core   +2 more sources

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

Molecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla, Jan Kosla, Magdalena Prechova, Lukas Frick, Patricia Bortel, Yasmin Borutzki, Andrea Bileck, Christopher Gerner, Samuel M. Meier‐Menches, Selma Osmanagic‐Myers, Martin Gregor   +10 more
wiley   +1 more source

Recent Developments in Functional Polymers via the Kabachnik–Fields Reaction: The State of the Art

Molecules
Recently, multicomponent reactions (MCRs) have attracted much attention in polymer synthesis. As one of the most well-known MCRs, the Kabachnik–Fields (KF) reaction has been widely used in the development of new functional polymers.
Rui Yuan, Xianzhe He, Chongyu Zhu, Lei Tao   +3 more
doaj   +1 more source

Glutathione-triggered disassembly of isothermally responsive polymer nanoparticles obtained by nanoprecipitation of hydrophilic polymers [PDF]

, 2013
The encapsulation and selective delivery of therapeutic compounds within polymeric nanoparticles offers hope for the treatment of a variety of diseases. Traditional approaches to trigger selective cargo release typically rely on polymer degradation which
Abulateefeh, Aleksanian, Cheng, Daniel J. Phillips, Duncan, Duncan, Duncan, Elsabahy, Fernàndez-Trillo, Fu, Fu, Gibson, Govender, Ieong, Joseph P. Patterson, Khorsand Sourkohi, Kim, Klaikherd, Li, Magnusson, Matthew I. Gibson, Musyanovych, Palamoor, Passarella, Peer, Petros, Phillips, Phillips, Putnam, Rachel K. O'Reilly, Saaka, Shah, Shepherd, Summers, Sun, van der Ende, van der Ende, Vert, Wang, Wu, Yang, Zhang   +41 more
core   +1 more source