Results 51 to 60 of about 682,509 (290)

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

Molecular dynamics simulations of glassy polymers

, 2009
We review recent results from computer simulation studies of polymer glasses, from chain dynamics around the glass transition temperature Tg to the mechanical behaviour below Tg.
Agapov, Aichele, Aichele, Alba-Simionesco, Alcoutlabi, Alexey Lyulin, Alexiadis, Andreanov, Angell, Angell, Baljon, Baljon, Baschnagel, Baschnagel, Bennemann, Bernabei, Bernabei, Berriot, Berthier, Berthier, Binder, Binder, Binder, Binder, Bohme, Boyce, Brodeck, Brüning, Buchholz, Bulacu, Bunker, Cavallo, Chaudhuri, Chen, Chong, Chong, Chopra, Chow, Colmenero, Colmenero, Colmenero, Colmenero, de Gennes, De Michele, Debenedetti, Ding, Dotson, Dudowicz, Ediger, Efremov, Ellison, Ellison, Fakhraai, Fakhraai, Fetters, Fetters, Flenner, Flenner, Foffi, Forrest, Forrest, Fredrickson, Fryer, Fuchs, Fukao, Fukao, Fukao, Gallo, Glotzer, Govaert, Granick, Grohens, Götze, Haward, Herminghaus, Herminghaus, Heuer, Hintermeyer, Hoy, Hoy, Hoy, Huth, Jain, Jain, Jain, Jean-Louis Barrat, Jörg Baschnagel, Keddie, Keys, Kim, Kim, Kob, Kob, Krakoviack, Krakoviack, Kramer, Krushev, Krushev, Kumar, Kunal, Lee, Likhtman, Lipson, Lobe, Lodge, Long, Lund, Lupaşcu, Lyulin, Lyulin, Lyulin, Lyulin, Lyulin, Lyulin, Makke, Manias, Mansfield, Mayer, Mayr, McCarty, McCoy, McKechnie, McLeish, Merabia, Merabia, Metatla, Meyer, Meyer, Meyer, Meyer, Mittal, Montes, Moreno, Moreno, Moreno, Morita, Murtola, Muthukumar, Müller-Plathe, Napolitano, Napolitano, Narros, Ngai, Oleinik, Papakonstantopoulos, Papakonstantopoulos, Papakonstantopoulos, Paul, Paul, Peter, Peter, Peter, Peter, Peter, Peter, Peter, Priestley, Riggleman, Riggleman, Riggleman, Riggleman, Riggleman, Rottler, Rottler, Rottler, Rottler, Rottler, Salamatina, Sarva, Scheidler, Scheidler, Scheidler, Schweizer, Serghei, Serghei, Servantie, Sharp, Signorini, Smith, Smith, Smith, Sokolov, Soldera, Sperl, Starr, Starr, Strauch, Sundararajan, Szamel, Tanguy, Teboul, Theodorou, Torres, Truskett, Tsalikis, Tsamados, Tsui, Utz, Vallee, Vallee, van Melick, van Melick, Van Workum, Varnik, Varnik, Varnik, Varnik, Vettorel, Vogel, Voigtmann, Vollmayr, Vollmayr, Vorselaars, Vorselaars, Warren, Wittmer, Xu, Yamamoto, Yan, Yoshimoto, Yoshimoto, Yoshimoto, Zaccarelli, Zamponi   +223 more
core   +3 more sources

Lanthanide grafted phenanthroline-polymer for physiological temperature range sensing [PDF]

, 2019
Accurate measurement of the temperature is crucial as it determines the dynamics of almost any system. Conventional contact thermometers are not well suited for small scale measurements. Temperature dependent luminescent materials, i.e.
Kaczmarek, Anna, Schmidt, Johannes, Stevens, Christian, Van Der Voort, Pascal, Vanden Bussche, Flore   +4 more
core   +1 more source

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

Molecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova, Zuzana Kozovska, Ondrej Pos, Kristina Pavlov, Sachin Gulati, Peter Makovicky, Kristina Jakic, Monika Burikova, Eva Sedlackova, Barbora Svitkova, Silvia Tyciakova, Vojtech Bystry, Nicolas Blavet, Boris Tichy, Matej Hrnciar, Jaroslav Budis, Miroslav Tomas, Peter Dubovan, Georgina Kolnikova, Veronika Repaska, Nikoleta Mojzesova, Eva Zomborska, Daniel Pindak, Michal Mego, Tomas Szemes, Miroslava Matuskova   +25 more
wiley   +1 more source

Liquid-Phase Chemical Sensing Using Lateral Mode Resonant Cantilevers [PDF]

, 2010
Liquid-phase operation of resonant cantilevers vibrating in an out-of-plane flexural mode has to date been limited by the considerable fluid damping and the resulting low quality factors (Q factors).
Beardslee, Luke A., Brand, Oliver, Demirci, Kemal S., Heinrich, Stephen M., Josse, Fabien, Luzinova, Y., Mizaikoff, B.   +6 more
core   +2 more sources

Surface Chemistry of Polymers [PDF]

Polymers, 2020
Surface chemistry plays a key role in modern applications of polymer materials [...]
openaire   +2 more sources

RIPK4 function interferes with melanoma cell adhesion and metastasis

Molecular Oncology, EarlyView.
RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski, Sławomir Lasota, Ewelina Madej, Anna A. Brożyna, Małgorzata Szczygieł, Agnieszka Harazin‐Lechowska, Jan Czerbniak, Janusz Rys, Jaroslaw Czyz, Agnieszka Wolnicka‐Glubisz   +9 more
wiley   +1 more source

Adhesives: Polymer Chemistry at Work

CHIMIA, 2008
Successful adhesive technology relies on the diligent engineering of adhesive and cohesive forces. Polymers thereby play the dominant role as they largely determine the chemical and physical properties of the adhesive joint.
Christof Arz, Andreas Dobmann, Olaf Meincke, Adrian Schulthess, Willi Schwotzer   +4 more
doaj   +1 more source

ATR-FTIR Spectroscopic Analysis of Sorption of Aqueous Analytes into Polymer Coatings Used with Guided SH-SAW Sensors [PDF]

, 2005
Attenuated total internal reflectance Fourier transform infrared (ATR-FTIR) spectroscopy was used for the investigation of sorption of aqueous solutions of analytes into polymer coatings. A series of simple model polymers, such as poly(dimethylsiloxane),
Hossenlopp, Jeanne, Johnson, Michael M., Jones, Yolanda K., Josse, Fabien, Li, Zhonghui   +4 more
core   +1 more source

Nanofiller-tuned microporous polymer molecular sieves for energy and environmental processes [PDF]

, 2015
10.1039/c5ta09060aJournal of Materials Chemistry A41270 ...
Cao, S, Cheetham, AK, Pritchard, RH, Qiblawey, H, Sivaniah, E, Song, Q, Terentjev, EM   +6 more
core   +1 more source