RIPK4 function interferes with melanoma cell adhesion and metastasis
Molecular Oncology, EarlyView.RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski +9 more
wiley +1 more source
COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells
Molecular Oncology, EarlyView.This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos +6 more
wiley +1 more source
Micro-patterning and actuation of phosphonium-based photo-responsive ionogels for micro-fluidic applications [PDF]
, 2011 The concept of “Micro-total-analysis-Systems” or “Lab-on-chip” has emerged over the past 20-years but, despite of the fact their incredible potential to revolutionise analytical science few outputs have reached the market so far[1].
Benito-Lopez, Fernando +3 more
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Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
Rheology Applied to Investigate Roofing Membranes: The Case of an Ecological Alternative
Applied Rheology, 2009 The viscoelastic performance indicators of a commercial roofing membrane and an ecological bituminous membrane, which contains EVA copolymer from disused greenhouses and filler from landfill, are investigated.
Goikoetxeaundia Goretti +3 more
doaj +1 more source
Micro-sized Polymer-Dispersed Liquid Crystal Modulator for TFT array defect Inspections [PDF]
, 2014 We proposed low driving voltage electro-optic (EO) modulator using the nano/micro-sized polymer-dispersed liquid crystal (PDCLC) for TFT array inspector.
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Bioengineered Textiles and Nonwovens – the convergence of bio-miniaturisation and electroactive conductive polymers for assistive healthcare, portable power and design-led wearable technology [PDF]
, 2009 Today, there is an opportunity to bring together creative design activities to exploit the responsive and adaptive ‘smart’ materials that are a result of rapid development in electro, photo active polymers or OFEDs (organic thin film electronic devices),
Oliver, Raymond +2 more
core +3 more sources
Rethinking plastic waste: innovations in enzymatic breakdown of oil‐based polyesters and bioplastics
FEBS Open Bio, EarlyView.Plastic pollution remains a critical environmental challenge, and current mechanical and chemical recycling methods are insufficient to achieve a fully circular economy. This review highlights recent breakthroughs in the enzymatic depolymerization of both oil‐derived polyesters and bioplastics, including high‐throughput protein engineering, de novo ...
Elena Rosini +2 more
wiley +1 more source
Stoyko Fakirov in the polymer science and technology
Advanced Industrial and Engineering Polymer Research, 2021 Klaus Friedrich, Ming Qiu Zhang
doaj +1 more source
Chemical research projects office: An overview and bibliography, 1975-1980 [PDF]
The activities of the Chemical Research Projects Office at Ames Research Center, Moffett Field, California are reported. The office conducts basic and applied research in the fields of polymer chemistry, computational chemistry, polymer physics, and ...
Heimbuch, A. H. +2 more
core +1 more source