Results 11 to 20 of about 1,273,483 (249)
Biophysical Chemistry, 2011 Molecular motors can exhibit Brownian ratchet or power stroke mechanisms. These mechanistic categories are related to transition state position: An early transition state suggests that chemical energy is stored and then released during the step (stroke) while a late transition state suggests that the release of chemical energy rectifies thermally ...
Galburt, E., Parrondo, J., Grill, S.
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International Journal of Molecular Sciences, 2019 Maintenance of genome integrity is a key process in all organisms. DNA polymerases (Pols) are central players in this process as they are in charge of the faithful reproduction of the genetic information, as well as of DNA repair. Interestingly, all eukaryotes possess a large repertoire of polymerases.
Pedroza-Garcia, Jose-Antonio +2 more
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RNA Polymerases of Maize: Nuclear RNA Polymerases [PDF]
Proceedings of the National Academy of Sciences, 1971 Two DNA-dependent RNA polymerases of nuclear origin have been purified from leaves of Zea mays . The two enzymes can be separated on DEAE-cellulose columns. Enzymes I and II are eluted with 0.08 and 0.20 M (NH 4 ) 2 SO 4 , respectively.
G C, Strain, K P, Mullinix, L, Bogorad
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Kufa Journal for Nursing Sciences, 2013 Objective: The present study aimed to determine the effectiveness of a polymerase chain reaction (PCR) technique for identification and differentiation of the cutaneous leishmaniasis parasite in clinical sample collected of lesion exudates patients ...
Haitham Mohammed Alawadi +1 more
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ANP32B, or not to be, that is the question for influenza virus
eLife, 2019 The evolutionary history of ANP32 proteins impacts how influenza virus jumps from birds to mammals.
Steven F Baker, Andrew Mehle
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Chronic Hepatitis B Treatment Strategies Using Polymerase Inhibitor-Based Combination Therapy
Viruses, 2021 Viral polymerase is an essential enzyme for the amplification of the viral genome and is one of the major targets of antiviral therapies. However, a serious concern to be solved in hepatitis B virus (HBV) infection is the difficulty of eliminating ...
Eriko Ohsaki +2 more
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DNA Helicase–Polymerase Coupling in Bacteriophage DNA Replication
Viruses, 2021 Bacteriophages have long been model systems to study the molecular mechanisms of DNA replication. During DNA replication, a DNA helicase and a DNA polymerase cooperatively unwind the parental DNA.
Chen-Yu Lo, Yang Gao
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Viruses, 2016 Rabbit haemorrhagic disease virus (RHDV) is a calicivirus that causes acute infections in both domestic and wild European rabbits (Oryctolagus cuniculus). The virus causes significant economic losses in rabbit farming and reduces wild rabbit populations.
Nadya Urakova +5 more
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Cell Reports, 2020 Summary: The ongoing global pandemic of coronavirus disease 2019 (COVID-19) has caused a huge number of human deaths. Currently, there are no specific drugs or vaccines available for this virus (SARS-CoV-2).
Qi Peng +11 more
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Журнал микробиологии, эпидемиологии и иммунобиологии, 2023 Introduction. The large fragment of DNA polymerase I from Geobacillus stearothermophilus GIM1.543 (Bst DNA polymerase) possesses 5'-3' DNA polymerase activity, 5'-3' displacement activity and high processivity.
Maria I. Pika +9 more
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