Results 11 to 20 of about 2,178,231 (341)
Are There Mutator Polymerases? [PDF]
The Scientific World JOURNAL, 2003 DNA polymerases are involved in different cellular events, including genome replication and DNA repair. In the last few years, a large number of novel DNA polymerases have been discovered, and the biochemical analysis of their properties has revealed a long list of intriguing features.
García Díaz, Miguel +4 more
openaire +6 more sources
Bst polymerase — a humble relative of Taq polymerase
Computational and Structural Biotechnology Journal, 2023 DNA polymerases are a superfamily of enzymes synthesizing DNA using DNA as a template. They are essential for nucleic acid metabolism and for DNA replication and repair. Modern biotechnology and molecular diagnostics rely heavily on DNA polymerases in analyzing nucleic acids.
Igor Oscorbin, Maxim Filipenko
openaire +3 more sources
RNA Polymerases of Maize: Nuclear RNA Polymerases [PDF]
Proceedings of the National Academy of Sciences, 1971 Two DNA-dependent RNA polymerases of nuclear origin have been purified from leaves of Zea mays . The two enzymes can be separated on DEAE-cellulose columns. Enzymes I and II are eluted with 0.08 and 0.20 M (NH 4 ) 2 SO 4 , respectively.
G C, Strain, K P, Mullinix, L, Bogorad
openaire +2 more sources
Characteristics of Pan-Cancer Patients With Ultrahigh Tumor Mutation Burden
Frontiers in Oncology, 2021 BackgroundTumor mutation burden has been proven to be a good predictor for the efficacy of immunotherapy, especially in patients with hypermutation. However, most research focused on the analysis of hypermutation in individual tumors, and there is a lack
Hong Yuan +13 more
doaj +1 more source
DNA polymerases in Biotechnology [PDF]
Frontiers in Microbiology, 2014 DNA polymerases are core tools for molecular biology including PCR, whole genome amplification, DNA sequencing and genotyping. Research has focused on discovery of novel DNA polymerases, characterization of DNA polymerase biochemistry and development of new replication assays. These studies have accelerated DNA polymerase engineering for biotechnology.
Gardner, Andrew F., Kelman, Zvi
openaire +5 more sources
Transcription-translation coupling: direct interactions of RNA polymerase with ribosomes and ribosomal subunits. [PDF]
, 2017 In prokaryotes, RNA polymerase and ribosomes can bind concurrently to the same RNA transcript, leading to the functional coupling of transcription and translation.
Blaha, Gregor M +9 more
core +1 more source
A new contribution to Megasporoporia sensu lato: Six new species and three new combinations
Frontiers in Microbiology, 2022 Megasporoporia sensu lato has recently been intensively studied in China and South America, and four independent clades representing four genera have been recognized phylogenetically. In this study, more samples, mostly from subtropical and tropical Asia,
Ya-Rong Wang +7 more
doaj +1 more source
Reconstitution of recombination-associated DNA synthesis with human proteins. [PDF]
, 2013 The repair of DNA breaks by homologous recombination is a high-fidelity process, necessary for the maintenance of genome integrity. Thus, DNA synthesis associated with recombinational repair must be largely error-free.
Grossi, Sara M +4 more
core +1 more source
Structure and Function of Caliciviral RNA Polymerases
Viruses, 2017 Caliciviruses are a leading agent of human and animal gastroenteritis and respiratory tract infections, which are growing concerns in immunocompromised individuals. However, no vaccines or therapeutics are yet available.
Ji-Hye Lee +2 more
doaj +1 more source
DNA polymerases required for repair of UV-induced damage in Saccharomyces cerevisiae [PDF]
, 1995 The ability of yeast DNA polymerase mutant strains to carry out repair synthesis after UV irradiation was studied by analysis of postirradiation molecular weight changes in cellular DNA.
Budd, Martin E., Campbell, Judith L.
core +2 more sources