Results 21 to 30 of about 1,273,483 (249)
Noroviruses (the Caliciviridae family) are a common cause of acute gastroenteritis in all age groups. These small non-envelope viruses with a single-stranded (+)RNA genome are characterized by high genetic variability.
E. V. Zhirakovskaia +5 more
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Mobile genetic element-encoded putative DNA primases composed of A-family polymerase—SSB pairs
Mobile genetic elements can encode a wide variety of genes that support their own stability and mobility as well as genes that provide accessory functions to their hosts.
Phoebe A. Rice
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Influenza A Virus PA Antagonizes Interferon-β by Interacting with Interferon Regulatory Factor 3
The influenza A virus (IAV) can be recognized by retinoic acid-inducible gene I (RIG-I) to activate the type I interferon response and induce antiviral effects.
Chenyang Yi +31 more
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Influenza viruses of types A and B attack 5–10% of adults and 20–30% of children, thereby causing millions of acute respiratory infections in Germany annually.
Duwe, Susanne C. +6 more
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Profilin and formin constitute a pacemaker system for robust actin filament growth
The actin cytoskeleton drives many essential biological processes, from cell morphogenesis to motility. Assembly of functional actin networks requires control over the speed at which actin filaments grow. How this can be achieved at the high and variable
Johanna Funk +8 more
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Viral polymerases play a central role in viral genome replication and transcription. Based on the genome type and the specific needs of particular virus, RNA-dependent RNA polymerase, RNA-dependent DNA polymerase, DNA-dependent RNA polymerase, and DNA-dependent RNA polymerases are found in various viruses.
openaire +2 more sources
A reverse transcriptase ribozyme
A highly evolved RNA polymerase ribozyme was found to also be capable of functioning as a reverse transcriptase, an activity that has never been demonstrated before for RNA. This activity is thought to have been crucial for the transition from RNA to DNA
Biswajit Samanta, Gerald F Joyce
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Aurintricarboxylic Acid Suppresses Hepatitis B Virus Replication by Inhibition of RNase H Activity
BackgroundChronic hepatitis B virus (HBV) infection is a global health threat for which there is an urgent need to develop novel therapeutics.MethodsAurintricarboxylic acid (ATA) has been demonstrated with broad-spectrum antimicrobial and antiviral ...
Meng Xu, Xiao Guan
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Across the three domains of life, B-family DNA polymerases play a variety of roles in both DNA repair and DNA replication processes. We examine the phenotypic consequences of loss of the putative repair polymerases PolB2 and/or PolB3 in the crenarchaeon ...
Peter B. Bohall +3 more
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Polymerase Chain Reaction [PDF]
The advent of the polymerase chain reaction (PCR) radically transformed biological science from the time it was first discovered (Mullis, 1990). For the first time, it allowed for specific detection and production of large amounts of DNA. PCR-based strategies have propelled huge scientific endeavors such as the Human Genome Project.
Garibyan, Lilit, Avashia, Nidhi
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