Results 321 to 330 of about 2,178,231 (341)
Some of the next articles are maybe not open access.
Current Opinion in Structural Biology, 2018
The eukaryotic DNA replication machinery is conserved from yeast to humans and requires the actions of multiple DNA polymerases. In addition to replicative DNA polymerases for duplication of the leading and lagging DNA strands, another group of specialized polymerases is required for DNA repair and/or translesion DNA synthesis (TLS).
Rinku, Jain +2 more
openaire +2 more sources
The eukaryotic DNA replication machinery is conserved from yeast to humans and requires the actions of multiple DNA polymerases. In addition to replicative DNA polymerases for duplication of the leading and lagging DNA strands, another group of specialized polymerases is required for DNA repair and/or translesion DNA synthesis (TLS).
Rinku, Jain +2 more
openaire +2 more sources
DNA Polymerase II, the Epsilon Polymerase of Saccharomyces cerevisiae
1993Publisher Summary This chapter discusses the data on DNA polymerase II in the context of current knowledge of eukaryotic DNA polymerases, DNA replication and its fidelity, and DNA repair. DNA polymerase II has been proffered as the “repair polymerase.” Contrary to the implicit assumption, DNA repair is not a single process but an array of different ...
A, Morrison, A, Sugino
openaire +2 more sources
Trends in Genetics, 1989
The polymerase chain reaction (PCR) is a powerful new method for 'in vitro cloning'. It can selectively amplify a single molecule of template DNA several millionfold in a few hours and has made possible new approaches to problems in molecular genetics, evolutionary biology, and development.
T J, White, N, Arnheim, H A, Erlich
openaire +2 more sources
The polymerase chain reaction (PCR) is a powerful new method for 'in vitro cloning'. It can selectively amplify a single molecule of template DNA several millionfold in a few hours and has made possible new approaches to problems in molecular genetics, evolutionary biology, and development.
T J, White, N, Arnheim, H A, Erlich
openaire +2 more sources
Biochemical and Biophysical Research Communications, 1971
Summary Homogeneous DNA polymerases from E. coli and sea urchins contain zinc in a proportion of approximately 2 and 4 gm atoms Zn/mole enzyme respectively. Specific inhibition of the enzyme by ortho -phenanthroline and lack of inhibition by meta -phenanthroline suggest that the bound zinc plays a functional role in the interaction of DNA with ...
J P, Slater, A S, Mildvan, L A, Loeb
openaire +2 more sources
Summary Homogeneous DNA polymerases from E. coli and sea urchins contain zinc in a proportion of approximately 2 and 4 gm atoms Zn/mole enzyme respectively. Specific inhibition of the enzyme by ortho -phenanthroline and lack of inhibition by meta -phenanthroline suggest that the bound zinc plays a functional role in the interaction of DNA with ...
J P, Slater, A S, Mildvan, L A, Loeb
openaire +2 more sources
Pinpointing a puzzling polymerase
Nature Structural & Molecular Biology, 2012One of the surprising discoveries in the genomic age was the presence in plant genomes of two noncanonical DNA-dependent RNA polymerases involved in small RNA–mediated gene silencing. Two recent studies map the binding sites of RNA polymerase V, uncovering new mysteries concerning the targeting and function of this enigmatic enzyme.
openaire +2 more sources
Polymerase Dependence of Autosticky Polymerase Chain Reaction
Analytical Biochemistry, 2000J, Gál, R, Schnell, M, Kálmán
openaire +2 more sources
Annual Review of Biochemistry, 1977
PERSPECTIVES A ND SU MMARY ......... 25 IN TR ODUCTION ........ ... 27 CE LLU LAR DNA POL YMERASES ....... . 28 DNA Polymerase a ......... 28 DNA Polymerase /3 31 DNA Polymerase 'Y •.....• • 33 Mitochondrial DNA Polymerase .... ......... 34 VIR US-INDUCED DNA POL YMERASES ......... ....
openaire +2 more sources
PERSPECTIVES A ND SU MMARY ......... 25 IN TR ODUCTION ........ ... 27 CE LLU LAR DNA POL YMERASES ....... . 28 DNA Polymerase a ......... 28 DNA Polymerase /3 31 DNA Polymerase 'Y •.....• • 33 Mitochondrial DNA Polymerase .... ......... 34 VIR US-INDUCED DNA POL YMERASES ......... ....
openaire +2 more sources