Results 101 to 110 of about 1,450,683 (312)

Targeting the AKT/mTOR pathway attenuates the metastatic potential of colorectal carcinoma circulating tumor cells in a murine xenotransplantation model

open access: yesMolecular Oncology, EarlyView.
Dual targeting of AKT and mTOR using MK2206 and RAD001 reduces tumor burden in an intracardiac colon cancer circulating tumor cell xenotransplantation model. Analysis of AKT isoform‐specific knockdowns in CTC‐MCC‐41 reveals differentially regulated proteins and phospho‐proteins by liquid chromatography coupled mass spectrometry. Circulating tumor cells
Daniel J. Smit   +19 more
wiley   +1 more source

The Design and Fabrication of Platform Device for Dna Amplification [PDF]

open access: yesDans Symposium on Design, Test, Integration and Packaging of MEMS/MOEMS - DTIP 2006, Stresa, Lago Maggiore : Italie (2006), 2007
Thermalcycler were extensively used machine for amplify DNA sample. One of the major problems in the working time was that it spent most of time for cooling and heating. In order to improve the efficient, this study presented a novel method for amplify DNA sample.
arxiv  

DIAGNOSIS OF MALARIA BY REAL-TIME POLYMERASE CHAIN REACTION IN CASES OF NEGATIVE MALARIAL PARASITE ON MICROSCOPY

open access: yesPakistan Armed Forces Medical Journal, 2020
Objective: To determine the frequency of malaria by polymerase chain reaction in malarial parasite negative samples on microscopy. Study Design: Cross-sectional study.
Hina Mushtaq   +5 more
doaj  

Development of Polymerase Chain Reaction assays with host-specific internal controls for Chlamydophila abortus

open access: yesVeterinární Medicína, 2015
Chlamydophila abortus (C. abortus) is one of the most important infectious agents causing abortion in ruminants. The bacterium is obligately intracellular, cannot grow on agar, but it needs cell culture or embryonated eggs for growth.
Z. Cantekin   +3 more
doaj   +1 more source

Aberrant expression of nuclear prothymosin α contributes to epithelial‐mesenchymal transition in lung cancer

open access: yesMolecular Oncology, EarlyView.
Nuclear prothymosin α inhibits epithelial‐mesenchymal transition (EMT) in lung cancer by increasing Smad7 acetylation and competing with Smad2 for binding to SNAI1, TWIST1, and ZEB1 promoters. In early‐stage cancer, ProT suppresses TGF‐β‐induced EMT, while its loss in the nucleus in late‐stage cancer leads to enhanced EMT and poor prognosis.
Liyun Chen   +12 more
wiley   +1 more source

DIAGNOSIS OF CANINE TRYPANOSOMOSIS BY POLYMERASE CHAIN REACTION [PDF]

open access: yesJournal of Veterinary and Animal Sciences, 2013
A clinical case of trypanosomosis in a German Shepherd dog and its diagnosis by polymerase chain reaction(PCR) was described.The dog was presented with clinical signs such as pyrexia, bilateral corneal opacity, pale mucous membranes, emaciation and ...
P.V.Tresamol   +4 more
doaj  

Bilateral hydronephrosis and hydroureter after ovariohysterectomy using nylon cable tie: a case report

open access: yesVeterinární Medicína, 2015
Chlamydophila abortus (C. abortus) is one of the most important infectious agents causing abortion in ruminants. The bacterium is obligately intracellular, cannot grow on agar, but it needs cell culture or embryonated eggs for growth.
L.R. Mesquita   +6 more
doaj   +1 more source

FSH enhances the inflammatory response of macrophages in the knee joint possibly through the NFκB pathway

open access: yesFEBS Open Bio, Volume 15, Issue 4, Page 622-633, April 2025.
We explored the role of FSH on the synovium and found that FSH was able to mediate the development of osteoarthritis by acting on the FSH receptor (FSHR) to promote the production and release of inflammatory factors through the activation of the NFκB signaling pathway. Previous studies have suggested that women with higher follicle‐stimulating hormone (
Yu Chen   +6 more
wiley   +1 more source

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