Results 201 to 210 of about 34,466 (298)

Epothilone B-based 3-in-1 polymeric micelle for anticancer drug therapy. [PDF]

Int J Pharm, 2017
Shin DH, Kwon GS.
europepmc   +1 more source

Freeze‐resistant, conductive semi‐interpenetrating network hydrogels enable oxidative stress regulation and enhanced wound healing

Interdisciplinary Medicine, EarlyView.
A multifunctional SFMA9/PF1 semi‐interpenetrating hydrogel with excellent conductivity, antioxidant activity, and freeze resistance effectively regulates the wound microenvironment, reduces oxidative stress and inflammation, promotes angiogenesis, and accelerates full‐thickness skin regeneration.
Xiaomin Sun, Yanqin Yu, Xinyuan He, Kaiyi Tang, Lijing Teng, Tianbao Qian, Zhu Zeng, Zuquan Hu   +7 more
wiley   +1 more source

A phase II study of NK012, a polymeric micelle formulation of SN-38, in unresectable, metastatic or recurrent colorectal cancer patients. [PDF]

Cancer Chemother Pharmacol, 2018
Hamaguchi T, Tsuji A, Yamaguchi K, Takeda K, Uetake H, Esaki T, Amagai K, Sakai D, Baba H, Kimura M, Matsumura Y, Tsukamoto T.   +11 more
europepmc   +1 more source

Recent progress on stimuli‐responsive chitosan‐based biomaterials as drug carriers

Interdisciplinary Medicine, EarlyView.
This review discusses the recent progress in chitosan‐based drug delivery systems that respond to pH, redox, enzymes, reactive oxygen species, and combined stimuli. It examines design strategies, key mechanisms, and therapeutic applications, and also addresses current challenges while suggesting future approaches to enhance clinical translation and ...
Changlu Xu, Yi‐Tung Lu, Bin Yang, Zhi Li, Kui Zeng   +4 more
wiley   +1 more source

Amphiphile Blending Controls Micelle Morphology to Enhance <i>In Vitro</i> Performance and Selective <i>In Vivo</i> mRNA Delivery to Lung and Spleen. [PDF]

JACS Au
Panda S, Eaton EJ, Sowada JP, Stelljes EM, Gilkey AK, Ismagilova S, Barnes JT, Moriarity BS, Reineke TM.   +8 more
europepmc   +1 more source

A fully absorbable biomimetic polymeric micelle loaded with cisplatin as drug carrier for cancer therapy. [PDF]

Regen Biomater, 2018
Zhuang W, Ma B, Liu G, Chen X, Wang Y.
europepmc   +1 more source

Turmeric and curcumin: From traditional medicine to modern therapeutic applications

JSFA reports, EarlyView.
Abstract Turmeric (Curcuma longa), a medicinal plant, has maintained its cultural and therapeutic significance over centuries in Ayurveda, Unani, and Traditional Chinese Medicine. However, novel formulations and delivery methods are being developed to address these challenges.
Azma Nadeem, Khurram Afzal, Asad Abbas, Talha Bin Iqbal, Abdul Malik, Javaria Saeed, Mutjardah Zarrish, Bipindra Pandey   +7 more
wiley   +1 more source

Recycling of hazelnut waste: Antidiabetic properties of soy lecithin nanoparticles and their in vitro anti‐proliferative effects in tumor cell lines

Journal of the Science of Food and Agriculture, EarlyView.
Abstract BACKGROUND Hazelnuts and foods produced using hazelnuts are consumed with pleasure, but it is important to evaluate the waste generated during hazelnut processing and determine their usage methods. RESULTS This study was conducted to determine the changes in bioactive components, bioaccessibility and antidiabetic activity of nanoparticles ...
Mehmet Ali Temiz, Emine Okumus
wiley   +1 more source

Predictive Modelling of Solvent Effects on Drug Incorporation into Polymeric Nanocarriers: A Machine Learning Approach

Macromolecular Rapid Communications, EarlyView.
When seeking nanoparticles with elevated drug loading content, the experimental setup, including solvent selection, is crucial. Through machine learning, we pinpointed that the drug's solubility in the organic solvent is the key factor for attaining high drug loading content.
Wei Ge, Ramindu De Silva, Yanan Fan, Scott A. Sisson, Martina H. Stenzel   +4 more
wiley   +1 more source

Mono‐ and Bivalent Poly(iso‐butylene)‐Alanines for Drug‐Delivery of Nimodipine and Triamcinolone Acetonide

Macromolecular Rapid Communications, EarlyView.
Mono‐ and bivalent‐, alanine‐modified poly‐iso‐butylenes, folding into beta‐sheets, were prepared by living carbocationic polymerization and subsequent endgroup modification. These PIB‐conjugates are useful as solid polymers for the drug release of triamcinolone and nimodipine. ABSTRACT Poly‐iso‐butylene (PIB) is a well known biocompatible polymer with
Philipp S. Hilgeroth, Julius F. Butter, Wolfgang H. Binder   +2 more
wiley   +1 more source