Results 241 to 250 of about 34,466 (298)
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Photo-responsive polymeric micelles
Soft Matter, 2014Photo-responsive polymeric micelles with different photo-reaction mechanisms and their applications in various fields have been discussed.
Yu, Huang +3 more
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Drug Loading of Polymeric Micelles
Pharmaceutical Research, 2012To gain mechanistic insights into drug loading and lyophilization of polymeric micelles.PEGylated poly-4-(vinylpyridine) micelles were loaded with dexamethasone. Three different methods were applied and compared: O/W emulsion, direct dialysis, cosolvent evaporation.
Miller, Tobias +6 more
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Continuous processing of paclitaxel polymeric micelles
International Journal of Pharmaceutics, 2021A continuous polymeric micelle processing platform was successfully developed, which eliminated batch-to-batch variation in critical quality attributes (for example, size and polydispersity that are typically associated with batch processing). A continuous precipitation process was achieved via coaxial turbulent jet in co-flow technology allowing ...
Anand Gupta +3 more
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Nano Today, 2012
Summary Polymeric micelles provide a platform that can be carefully tuned for drug delivery. The nano-scale aggregates form spontaneously in aqueous solution and can be used to overcome drug insolubility and increase circulation half life. Self-assembled polymeric micelles are dynamic in nature; thermodynamics defines how the system acts as micelles ...
Shawn C. Owen +2 more
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Summary Polymeric micelles provide a platform that can be carefully tuned for drug delivery. The nano-scale aggregates form spontaneously in aqueous solution and can be used to overcome drug insolubility and increase circulation half life. Self-assembled polymeric micelles are dynamic in nature; thermodynamics defines how the system acts as micelles ...
Shawn C. Owen +2 more
openaire +1 more source
Polymeric Micelles with Tunable Channels
Macromolecular Bioscience, 2010AbstractThis article describes a novel type of polymeric micelles with tunable channels (PMTC), which are usually composed of a common core and a mixed shell of two different kinds of polymer chains with at least one of them being stimuli‐responsive. Phase separation of the mixed shell upon stimuli results in channels between the micelle core and the ...
Rujiang, Ma, Linqi, Shi
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Polymeric Micelles for Drug Delivery
Current Pharmaceutical Design, 2006Polymeric micelles are nanoscopic core/shell structures formed by amphiphilic block copolymers. Both the inherent and modifiable properties of polymeric micelles make them particularly well suited for drug delivery purposes. An emphasis of this review has been placed on both the description and characterization techniques of the physical properties of ...
S R, Croy, G S, Kwon
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Rupturing Polymeric Micelles with Cyclodextrins
Langmuir, 2006Small-angle neutron scattering has been used to investigate the associative structures formed by triblock copolymers of poly(ethylene oxide) (PEO)-polypropylene oxide (PPO)-poly(ethylene oxide) (PEO) (also known as Pluronics) and to monitor the structural changes occurring upon complexation with heptakis(2,6-di-O-methyl)-beta-cyclodextrin (hbeta-CD ...
Joseph, J +3 more
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Polymeric Micelles with Mesoporous Cores
ACS Macro Letters, 2013Mesoporous polymer nanoparticles containing pores with sizes ranging from 2 to 50 nm are attractive for wide applications, such as catalysis, drug delivery, and separations. On the basis of nanometer-sized phase separation and cleavage reaction in the micellar cores, polymeric micelles with mesoporous cores are prepared in this research.
Yue, Zhang +3 more
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Polymeric micelles for drug targeting
Journal of Drug Targeting, 2007Polymeric micelles are nano-delivery systems formed through self-assembly of amphiphilic block copolymers in an aqueous environment. The nanoscopic dimension, stealth properties induced by the hydrophilic polymeric brush on the micellar surface, capacity for stabilized encapsulation of hydrophobic drugs offered by the hydrophobic and rigid micellar ...
Abdullah, Mahmud +3 more
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Polymeric micelles for drug delivery
Expert Opinion on Drug Delivery, 2005Polymeric micelles have been the subject of many studies in the field of drug delivery for the past two decades. The interest has specifically been focused on the potential application of polymeric micelles in three major areas in drug delivery: drug solubilisation, controlled drug release and drug targeting.
Hamidreza Montazeri, Aliabadi +1 more
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