Results 141 to 150 of about 2,130,838 (296)

Polymeric micelles in advanced photodynamic therapy: Design, delivery and translational prospects. [PDF]

Int J Pharm X
Turnovská A, Etrych T.
europepmc   +1 more source

Lycopene‐rich food biomolecules from tomato processing waste: Green recovery, biopolymer‐based stabilisation, functional food applications and health relevance

Food Biomacromolecules, EarlyView.
Abstract Tomato processing waste, particularly peel and pomace, is a sustainable and low‐cost source of lycopene‐rich food biomolecules. Lycopene, a lipophilic carotenoid with an extended conjugated structure, provides intense red colour, antioxidant potential and functional value to tomato‐derived ingredients.
Chandan Kumar Sahu, Mrinmoy Roy
wiley   +1 more source

OCTN2-targeted and ROS-responsive hybrid polymeric micelles for oral delivery of docetaxel. [PDF]

J Nanobiotechnology
Sun H, Gou J, Bi X, Song J, Liu B, Jin X, Sui B, Jin X.   +7 more
europepmc   +1 more source

In Vitro Raman Spectroscopic Characterization of Docetaxel‐Loaded Polymeric Nanoparticles

Helvetica Chimica Acta, EarlyView.
The chemotherapeutic drug docetaxel(DTX) is nanoformulated using Soluplus, Soluplus–TPGS, and Pluronic micelles and characterized by label‐free in vitro FT‐Raman spectroscopy. Distinct DTX Raman signatures confirm successful drug incorporation, while spectral decomposition reveals the superior performance of Soluplus–TPGS mixed micelles, paving the way
Sankar Jana, Emma Reig‐Martí, Constanze Schultz, Michael Schmitt, Tobias Meyer‐Zedler, S M Miftahul Islam, Iwan W. Schie, Ibane Abasolo, Miriam Royo, Juergen Popp   +9 more
wiley   +1 more source

Mitochondria‐targeted nanomedicine for cancer therapy: Targeting strategies, therapeutic mechanisms, and translational challenges

Interdisciplinary Medicine, EarlyView.
This review highlights recent advances in mitochondria‐targeted nanomedicine for cancer therapy. It summarizes key targeting strategies and delineates four principal therapeutic mechanisms: oxidative stress–induced mitochondrial dysfunction, disruption of energy metabolism, direct mitochondrial damage, and induction of immunogenic cell death.
Linfeng Xiao, Xiaowei Chang, Jun Zhang, Yinshan Hong, Wenhui Cao, Zhewu Zhao, Yu‐E. Wang, Yanling Yang   +7 more
wiley   +1 more source

Development and Characterization of Citalopram-Loaded Thermosensitive Polymeric Micelles for Nasal Administration. [PDF]

Pharmaceutics
Rajab F, Sipos B, Katona G, Csóka I.
europepmc   +1 more source

Alpha‐Synuclein Promotes Anterograde Vesicle Transport in Melanocytes and Melanoma Cells: A Pro‐Survival Function

Journal of the Chinese Chemical Society, EarlyView.
Model for how α‐syn modulates the positioning of endolysosomes in melanoma cells. (a) α‐syn tethers endolysosomes to the plasma membrane, a last step in anterograde transport. (b) Loss of α‐syn expression causes the loss of the tethering function, which leads to perinuclear vesicle clustering. Reproduced from the open access article.
Stephan N. Witt
wiley   +1 more source

Development of a reverse-phase HPLC method for the simultaneous determination of curcumin and dexamethasone in polymeric micelles. [PDF]

Future Sci OA
Haj-Ali D, Azzam H, Aiedeh K, Alshaer W.
europepmc   +1 more source

Physical stability of RNA–lipid nanoparticles under agitation, freeze–thaw and accelerated stability testing

Journal of Chemical Technology &Biotechnology, EarlyView.
Abstract BACKGROUND The choice of excipient is important in enhancing stability of liquid formulations containing lipid nanoparticles (LNPs) used in RNA delivery where the ability to survive unplanned excursions to higher and lower temperature and vibration is an important attribute.
Franz W Laurett Veras, Leah Wright, Robert J Falconer   +2 more
wiley   +1 more source

Antioxidant and Neuroprotective Capacity of Resveratrol-Loaded Polymeric Micelles in In Vitro and In Vivo Models with Generated Oxidative Stress. [PDF]

Biomedicines
Lazarova M, Tsvetanova E, Georgieva A, Stefanova M, Tasheva K, Radeva L, Kondeva-Burdina M, Yoncheva K.   +7 more
europepmc   +1 more source