Results 121 to 130 of about 277,094 (244)

Neutral Polymeric Micelles for RNA Delivery

, 2013
RNA interference (RNAi) drugs have significant therapeutic potential, but delivery systems with appropriate efficacy and toxicity profiles are still needed.
Convertine, Anthony J., Stayton, Patrick S., Lundy, Brittany B., Miteva, Martina   +3 more
core   +1 more source

Self‐Assembled Pt(II) Complexes Boost Up Stem Cell Proliferation and Accelerate Metamorphosis in Living Organisms

Angewandte Chemie, EarlyView.
Pt1, an organometallic platinum‐based complex, act as a modulator of redox homeostasis in cnidarians, regulating cellular functions and life‐cycle dynamics. In Nematostella vectensis, it mitigates oxidative stress, strengthens detox systems and accelerates development.
Giuseppina Tommasini, Tania Pecoraro, Anna Lewinska, Maciej Wnuk, Olga Kolodziej, Daniela Intartaglia, Simona Morgera, Alessandro Aliprandi, Giulia Veronesi, Giorgio Facchetti, Isabella Rimoldi, Angela Tino, Claudia Tortiglione, Luisa De Cola   +13 more
wiley   +2 more sources

Multispectral optoacoustic tomography (MSOT) for imaging the particle size-dependent intratumoral distribution of polymeric micelles

International Journal of Nanomedicine, 2018
Zhaoqing Cong, Feifei Yang, Li Cao, Han Wen, Taotao Fu, Siqi Ma, Chunyu Liu, Lihui Quan, Yonghong Liao Key Laboratory of Bioactive Substances and Resources Utilization of Chinese Herbal Medicine, Institute of Medicinal Plant Development, Chinese Academy
Cong ZQ, Yang FF, Cao L, Wen H, Fu TT, Ma SQ, Liu CY, Quan LH, Liao YH   +8 more
doaj  

Microfluidic reactors for controlled synthesis of polymeric micelles

, 2010
This study outlines the relationship between polymer concentration, flow rate ratio and microreactor dimension and the size of polymeric micelles produced in continuous flow microreactors.
Wei Chengx, Zhang, Xunli, Lorenzo Capretto, Cheng, Wei, Dario Carugo, Capretto, Lorenzo, Carugo, Dario, Xunli Zhang, Hill, Martyn, Martyn Hill   +9 more
core   +1 more source

Helical Single Crystals of Porous Hydrogen‐Bonded Organic Frameworks as a Candidate for Morphologically Functional Organic Materials

Angewandte Chemie, EarlyView.
Helical‐shaped crystals of a hydrogen‐bonded organic framework (HOF) with permanent porosity have been developed. The helical HOF shows expansion and contraction, respectively, upon desorption and adsorption of solvents. Moreover, doping of additive molecules can modulate the photophysical properties and morphology of the helical HOF, showing the ...
Yuzuki Murata, Taito Hashimoto, Ryusei Oketani, Miki Naruoka, Yuuya Nagata, Ryosuke Tamura, Masayuki Morimoto, Mio Yamashita, Daisuke Sakamaki, Norimitsu Tohnai, Hitoshi Asakawa, Ichiro Hisaki   +11 more
wiley   +2 more sources

Folate-targeted paclitaxel-conjugated polymeric micelles inhibits pulmonary metastatic hepatoma in experimental murine H22 metastasis models

, 2014
Yan Zhang,1 Hui Zhang,2 Wenbin Wu,2 Fuhong Zhang,3,4 Shi Liu,3 Rui Wang,3 Yingchun Sun,1 Ti Tong,1 Xiabin Jing3 1Department of Thoracic Surgery, The Second Hospital of Jilin University, Changchun, Jilin, People's Republic of China; 2Department of ...
Wu WB, Zhang FH, Wang R, Jing XB, Zhang Y, Zhang H, Liu S, Sun YC, Tong T   +8 more
core  

One‐Pot Synthesis of Aqueous PEDOT‐Based Conductive Inks via Sequential RAFT/Oxidative Polymerization

Angewandte Chemie, EarlyView.
We developed a fast, aqueous one‐pot synthesis for PEDOT:PSTFSI, combining sequential reversible addition–fragmentation chain‐transfer (RAFT) and oxidative polymerization. This method eliminates toxic solvents and purification steps, achieving full monomer conversion in under 3 h.
Fantine Negny, Melanie Bousquet, Benjamin Cabannes‐Boué, Pierre‐Yves Dugas, Lionel Hirsch, Thiago R. Guimaraes, Eric Cloutet   +6 more
wiley   +2 more sources

Neutral Polymeric Micelles for RNA Delivery

, 2016
RNA interference (RNAi) drugs have significant therapeutic potential, but delivery systems with appropriate efficacy and toxicity profiles are still needed.
Patrick S. Stayton (1881700), Anthony Convertine (1954570), Martina Miteva (1349562), Brittany B. Lundy (1978768)   +3 more
core   +1 more source

Oxygen‐Tolerant, Controlled Synthesis of Degradable and Water‐Soluble Poly(Vinyl Amide)s via Radical Ring‐Opening Copolymerization of Cyclic Dithiothreitol

Angewandte Chemie, EarlyView.
Oxygen‐tolerant photoinduced electron/energy transfer reversible addition–fragmentation chain transfer (PET‐RAFT) polymerization enables the controlled radical ring‐opening (rROP) copolymerization of cyclic dithiothreitol (cDTT) with less‐activated vinyl monomers, affording degradable polymers with predictable molecular weights, low dispersities, and ...
Alessandro Magro, Ivan O. Levkovsky, Hironobu Murata, Francesca Lorandi, Edmondo M. Benetti, Krzysztof Matyjaszewski   +5 more
wiley   +2 more sources

Polymeric micelles for drug delivery: from synthesis to in vivo studies [PDF]

, 2014
Drug delivery systems have been extensively utilized to increase water-solubility of hydrophobic chemotherapeutic drugs and target the drugs to tumors, which enhances the efficacy of chemotherapy and simultaneously decreases non-specific disposition of ...
Shi, Yang, Pharmaceutics, Sub General Pharmaceutics   +2 more
core