Results 101 to 110 of about 277,094 (244)

Polymer Concepts in Cellular Function

Advanced Science, EarlyView.
Miao Yu, Shikha Dhiman, Dorothee Dormann, Frauke Gräter, Katja Luck, Friederike Schmid, Andreas Walther, Edward A. Lemke   +7 more
wiley   +1 more source

ROS‐Responsive Nanoparticle Delivery of Dexmedetomidine Protects the Gut Vascular Barrier After Intestinal Ischemia/Reperfusion via the HDAC‐H3K27ac‐TCF4 Axis

Advanced Science, EarlyView.
A low dose of dexmedetomidine, delivered by ROS‐responsive nanoparticles, preferentially accumulates in the ischemic intestine and restores gut vascular barrier integrity after ischemia/reperfusion injury. This nanoparticle‐based strategy prevents bacterial translocation and liver damage without cardiorespiratory side effects, working through HDAC ...
Hu‐Fei Zhang, Jian‐Tong Shen, Hua‐Hua Zhang, Si‐Qi Gao, Ji‐Ao Wang, Yue‐Ling Wang, Mei‐Ling Li, Zi‐Meng Liu, Yi‐Nan Zhang, Yan Li, Xu‐Yu Zhang   +10 more
wiley   +1 more source

Click'n ROPISA: One‐Pot Synthesis of Ultrabright Fluorescent Nanoparticles Made of Polypeptides

Angewandte Chemie, EarlyView.
Self‐assembly and fluorophore conjugation proceed rapidly in a one‐pot “Click'n ROPISA” process, yielding intensely fluorescent polypeptide nanoparticles with tunable visible emission. High dye loading enables efficient energy transfer and single‐particle visualization, while the straightforward synthesis provides versatile access to bright ...
Amin El Jarroudi Hammou, Juliette Lavainne, Rohit Mangalwedhekar, Jyothis Devasia, Laurent Cognet, Sébastien Lecommandoux, Colin Bonduelle, Chloé Grazon   +7 more
wiley   +2 more sources

RGD peptide-mediated chitosan-based polymeric micelles targeting delivery for integrin-overexpressing tumor cells

, 2011
Li-Li Cai1, Ping Liu1, Xi Li1, Xuan Huang2, Yi-Qing Ye3, Feng-Ying Chen3, Hong Yuan1, Fu-Qiang Hu1, Yong-Zhong Du11College of Pharmaceutical Science, Zhejiang University, Hangzhou, 2Department of Pharmacy, School of Medicine, Jiaxing College, Jiaxing ...
Li X, Hu FQ, Du YZ, Huang X, Liu P, Ye YQ, Yuan H, Cai LL, Chen FY   +8 more
core  

Polymeric Micelles: Principles, Perspectives and Practices

, 2023
This book thoroughly reviews the advancements in design and applications of Polymeric Micelles (PMs) in drug ...
Mutalik, S, Dua, K, Dhanasekaran, M, Singh, SK, Gulati, M   +4 more
core  

Pathological Signal‐Responsive Nanoplatforms for Sepsis: Integrating Biomarker Sensing With Spatiotemporal Drug Delivery and Immunomodulation

Advanced Science, EarlyView.
Biomarker‐triggered nanoplatforms transform sepsis therapy by coupling pathological sensing with precision drug release. This review reveals how microenvironment‐responsive nanomedicines enable stage‐specific intervention, improve therapeutic efficacy, and minimize systemic toxicity, while highlighting emerging opportunities for AI‐assisted and ...
Yukun Liu, Kang Wang, Kwet Kyawl Yan, Zhikai Xu, Xuan Zhao, Xiangjun Bai, Zhanfei Li, Yuchang Wang   +7 more
wiley   +1 more source

Biodegradable polymeric micelles coencapsulating paclitaxel and honokiol: a strategy for breast cancer therapy in vitro and in vivo

, 2017
Ning Wang, Zhihan Wang,* Shihong Nie,* Linjiang Song, Tao He, Suleixin Yang, Xi Yang, Cheng Yi, Qinjie Wu, Changyang Gong State Key Laboratory of Biotherapy and Cancer Center, Collaborative Innovation Center for Biotherapy, West China Hospital, Sichuan ...
Song L, Yang X, Wang N, Nie S, He T, Gong C, Wu Q, Yi C, Wang Z, Yang S   +9 more
core  

Beyond Conventional: A Review of Phytochemical‐Hydrogel Systems Enhanced by AI and 3D Printing for Chronic Wound Management

Advanced Science, EarlyView.
This review systematically bridges chronic wound pathology with natural phytochemical hydrogel therapeutics. A pathology‐to‐phytochemical mechanistic mapping framework is established, linking specific wound hallmarks to targeted phytochemical interventions.
Yitao Zhou, Xing Liu, Cuiyi Wang, Xiaoxuan Zhao, Pengrun Zhang, Jingjing Gu, Qiuhua Sun, Malcolm Xing, Yeqin Yang   +8 more
wiley   +1 more source

Monolithic Porous Polymer Architectures for Visible‐to‐UV Upconversion‐Driven Photochemical Reactions

Angewandte Chemie, EarlyView.
Porous polymer monoliths embedded with sensitizer–annihilator dye pairs enable efficient solid‐state visible‐to‐ultraviolet triplet–triplet annihilation‐based photon upconversion under low‐intensity blue and green light. Their co‐continuous porous architectures balance chromophore interactions with substrate accessibility, providing robust and tunable ...
Sakura Nakagawa, Naoto Matsumoto, Masanori Uji, Maria‐Sophie Bertrams, Christoph Kerzig, Nobuhiro Yanai   +5 more
wiley   +2 more sources

The Antidiabetic Potential of Alpha‐Mangostin: A Review of Preclinical and Clinical Evidence

AgriFood: Journal of Agricultural Products for Food, EarlyView.
Alpha‐mangostin is a compound from the pericarp of Garcinia mangostana. The antidiabetic effects of alpha‐mangostin include enhancing insulin secretion, improving glucose uptake through GLUT receptor upregulation, reducing oxidative stress and inflammation, promoting wound healing, reducing HbA1C, reducing HOMA‐IR index, and decreased mRNA expressions ...
Oliver Dean John, Nur Damia Iwani Zulkiflee, Siti Raihanah Shafie, Ramlah George, Melonney Patrick   +4 more
wiley   +1 more source