Results 81 to 90 of about 277,094 (244)

Development and Evaluation of a Water Soluble Fluorometholone Eye Drop Formulation Employing Polymeric Micelle

open access: yesPharmaceutics, 2018
Low aqueous solubility of drug causes difficulties in preparation and inconvenience of administration. Polymeric micelles of fluorometholone (FML) using solid dispersion technique were prepared to develop an eye drop formulation with enhanced water ...
Gyubin Noh   +8 more
doaj   +1 more source

Polymeric micelles for acyclovir drug delivery

open access: yes, 2014
Polymeric prodrug micelles for delivery of acyclovir (ACV) were synthesized. First, ACV was used directly to initiate ring-opening polymerization of e{open}-caprolactone to form ACV-polycaprolactone (ACV-PCL).
Sawdon, Alicia J., Peng, Ching An
core   +1 more source

Engineering Ultrastable Intrinsic Radicals: Graphene Quantum Dots With NIR‐II Emission for Dynamic Deep‐Tissue Bioimaging

open access: yesAdvanced Science, EarlyView.
Stable radicals are attractive for photonic and quantum information technologies but are often limited by instability. We stabilize intrinsic radicals in graphene quantum dots via 2D polymerization of perylene derivatives, where bilayer defect confinement suppresses quenching (100–500 K).
Qin Xu   +9 more
wiley   +1 more source

PEG-Derivatized Dual-Functional Nanomicelles for Improved Cancer Therapy

open access: yesFrontiers in Pharmacology, 2019
Polymeric micelles have attracted considerable attention for effective delivery of poorly water-soluble cancer drugs. Polyethylene glycol (PEG), which has been approved for human use by the US Food and Drug Administration, is the most commonly used ...
Yanping Li   +4 more
doaj   +1 more source

Bypassing Heteronuclear MRI: Metal‐Free Organosilicon Nanotracers for Background‐Free Hotspot 1H Imaging on Clinical Hardware

open access: yesAdvanced Science, EarlyView.
Organosilicon micelles enable background‐free molecular magnetic resonance imaging (MRI) while remaining fully compatible with standard proton (1H) hardware. By exploiting a spectrally silent 1H window at ∼0 ppm, the silicone nanotracer allows hotspot detection by 1H chemical‐shift imaging (CSI) without metals or heteronuclei, enabling direct overlay ...
Martin Orsagh   +4 more
wiley   +1 more source

Colloidal Drug Delivery Systems – Recent Advances With Polymeric Micelles

open access: yesCHIMIA, 2008
With the emergence of nanotechnology in drug delivery, colloidal systems and particularly polymeric micelles have attracted great attention. Polymeric micelles formed by the self-assembly of amphiphilic copolymers adopt a core-shell structure ...
Karine Mondon   +2 more
doaj   +1 more source

Triple‐Helix Biomolecules Construct Self‐Adaptive Multi‐Phase Interfaces for Dendrites Immunized Zinc Metal Anodes

open access: yesAdvanced Science, EarlyView.
A bio‐derived triple‐helix framework enables adaptive interphase engineering for aqueous Zn metal batteries. Directional Zn2+ migration channels and dynamic transformation into β‐sheet domains construct an optimized solid electrolyte interphase with flexible–rigid synergy, delivering dendrite‐free Zn deposition and exceptional long‐term battery cycling
Tianyi Wang   +11 more
wiley   +1 more source

Characterization of astaxanthin encapsulated mPEG-PCL polymeric micelles.

open access: yes, 2019
(A) Representative particle size distribution of mPEG-PCL polymeric micelles and astaxanthin-encapsulated mPEG-PCL polymeric micelles. The average size of mPEG-PCL polymeric micelles was 87.1 ± 9.1 nm; the average size of astaxanthin-encapsulated mPEG ...
Jun Zhang (48506), Ching-An Peng (49628)
core   +1 more source

Recapitulating In Vivo Pharmacokinetics and Size‐Dependent Nanomedicine Delivery in a Microfluidic Platform

open access: yesAdvanced Science, EarlyView.
A microfluidic tumor platform integrates pharmacokinetic flow control, vascular‐like barriers, and 3D tumor spheroids to emulate in vivo drug exposure. The system reproduces dynamic concentration–time profiles and enables size‐dependent nanoparticle transport and efficacy evaluation, providing a predictive framework for assessing nanomedicine ...
Su Jeong Kang   +5 more
wiley   +1 more source

Poly(Ethylene Glycol)–Polylactide Micelles for Cancer Therapy

open access: yesFrontiers in Pharmacology, 2018
For the treatment of malignancy, many therapeutic agents, including small molecules, photosensitizers, immunomodulators, proteins and genes, and so forth, have been loaded into nanocarriers for controllable cancer therapy.
Jixue Wang   +8 more
doaj   +1 more source

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