Results 61 to 70 of about 333,924 (199)

Micellization model for the polymerization of clathrin baskets [PDF]

open access: yesThe Journal of Chemical Physics, 2013
A thermodynamic model is used to investigate the conditions under which clathrin triskelions form polyhedral baskets. The analysis, which is similar to classical methods used to study micelle formation, relates clathrin basket energetics to system parameters linked to triskelial rigidity, the natural curvature of an isolated triskelion, and ...
M, Muthukumar, Ralph, Nossal
openaire   +2 more sources

Reduction of protein adsorption on surfaces coated with Complex Coacercate Core Micelles [PDF]

open access: yes, 2010
The structure and formation of Ionomer Complexes (ICs) consisting of linear polyelectrolytes (C3Ms) has been extensively studied in the past years. Recently, these structures were also considered for several applications.
Brzozowska, A.M.
core  

Exploring Polymeric Micelles for Improved Delivery of Anticancer Agents: Recent Developments in Preclinical Studies

open access: yesPharmaceutics, 2013
As versatile drug delivery systems, polymeric micelles have demonstrated particular strength in solubilizing hydrophobic anticancer drugs while eliminating the use of toxic organic solvents and surfactants. However, the true promise of polymeric micelles
Wei Fan, Yingzhe Wang, Chalet Tan
doaj   +1 more source

The synthesis and ring-opening polymerisation of novel cyclic esters from malic acid [PDF]

open access: yes
The work in this thesis is directed towards the preparation of cyclic ester monomers using malic acid as a renewable resource. Their subsequent controlled ring-opening polymerisation (ROP) to yield functionalised poly(ester)s is studied and ...
Pounder, Ryan J.
core  

Advances in Polymer Micelles for Cancer Therapy: From Conventional to Smart Delivery Systems

open access: yesPharmaceutics
Polymeric micelles have become a versatile and clinically significant class of nanocarriers for cancer therapy. They effectively solubilize poorly water-soluble anticancer drugs, extend their circulation in the bloodstream, and promote accumulation in ...
Rayna Georgieva Bryaskova   +2 more
doaj   +1 more source

MRI-detectable polymeric micelles incorporating platinum anticancer drugs enhance survival in an advanced hepatocellular carcinoma model

open access: yes, 2015
Nguyen Quoc Vinh,1 Shigeyuki Naka,1 Horacio Cabral,2 Hiroyuki Murayama,1 Sachiko Kaida,1 Kazunori Kataoka,2 Shigehiro Morikawa,3 Tohru Tani4 1Department of Surgery, Shiga University of Medical Science, Shiga, Japan; 2Department of Bioengineering ...
Morikawa S   +7 more
core  

Liposomal and Micellar-Based Nanoformulations of Fluorinated Curcumin Derivative and Naringenin—Comparative Studies

open access: yesNanomaterials
Background/Objectives: Poor aqueous solubility and low bioavailability limit the therapeutic use of many hydrophobic anticancer agents. This study developed liposomal and polymeric micellar formulations of a fluorinated curcumin derivative (FCur) and ...
Joanna Kuzminska   +9 more
doaj   +1 more source

Development and Evaluation of a Water Soluble Fluorometholone Eye Drop Formulation Employing Polymeric Micelle

open access: yesPharmaceutics, 2018
Low aqueous solubility of drug causes difficulties in preparation and inconvenience of administration. Polymeric micelles of fluorometholone (FML) using solid dispersion technique were prepared to develop an eye drop formulation with enhanced water ...
Gyubin Noh   +8 more
doaj   +1 more source

Stimuli-responsive polymeric micelles for drug delivery and cancer therapy

open access: yes, 2018
Qing Zhou,1,* Li Zhang,2,* TieHong Yang,1 Hong Wu1 1Department of Pharmaceutical Analysis, School of Pharmacy, Air Force Military Medical University, Xi’an, People’s Republic of China; 2State Key Laboratory of Military Stomatology, Air Force
Zhou Q, Zhang L, Yang T, Wu H
core  

PEG-Derivatized Dual-Functional Nanomicelles for Improved Cancer Therapy

open access: yesFrontiers in Pharmacology, 2019
Polymeric micelles have attracted considerable attention for effective delivery of poorly water-soluble cancer drugs. Polyethylene glycol (PEG), which has been approved for human use by the US Food and Drug Administration, is the most commonly used ...
Yanping Li   +4 more
doaj   +1 more source

Home - About - Disclaimer - Privacy