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Polymeric Micelles for the Treatment of Rheumatoid Arthritis

Critical Reviews™ in Therapeutic Drug Carrier Systems, 2019
Rheumatoid arthritis (RA) affects around 1% of the world's population and places heavy burdens on patients and society. RA pathogenesis has been studied for centuries, and findings suggest that it is activated by varied factors such as infection, genetic activation, and environmental changes, and travels differential pathways in patients, which ...
Linsen, Yun   +3 more
openaire   +2 more sources

Polymeric micelles for oral drug delivery

European Journal of Pharmaceutics and Biopharmaceutics, 2010
In the case of chronic therapies, the oral route is often the preferred route for drug administration given its acceptability and convenience. However, various factors which limit drug absorption through the gastro-intestinal (GI) mucosa contribute to restricting the bioavailability of the drug, that is, the actual amount which reaches the bloodstream.
Geneviève, Gaucher   +4 more
openaire   +2 more sources

Polymeric micelles encapsulating pH‐responsive doxorubicin prodrug and glutathione‐activated zinc(II) phthalocyanine for combined chemotherapy and photodynamic therapy

Journal of Controlled Release, 2018
A series of polymeric micelles encapsulating different ratios of doxorubicin (DOX) and zinc(II) phthalocyanine (ZnPc) have been prepared for dual chemotherapy and photodynamic therapy (PDT). The amphiphilic block copolymers consist of methoxypolyethylene
Di Gao, P. Lo
semanticscholar   +1 more source

Pluronic-Based Mixed Polymeric Micelles Enhance the Therapeutic Potential of Curcumin

AAPS PharmSciTech, 2018
Curcumin is a naturally occurring constituent of turmeric that is a good substitute for synthetic medicines for the treatment of different diseases, due to its comparatively safer profile.
M. Akbar   +5 more
semanticscholar   +1 more source

Reverse polymeric micelles for pharmaceutical applications

Journal of Controlled Release, 2008
Star-shaped (4- to 8-arms) and linear poly(glycidyl methacrylate)s were synthesized by atom transfer radical polymerization as precursors of poly(glycerol methacrylate)s (PG(OH)MAs). The water-soluble PG(OH)MA backbones were modified through the esterification of pendant hydroxyl functions with acyl chlorides (12 to 18 carbons). Alkyated PG(OH)MAs were
Marie-Christine, Jones   +2 more
openaire   +2 more sources

Thermo- and pH dual responsive polymeric micelles and nanoparticles.

Chemico-Biological Interactions, 2018
A new generation of the more effective polymeric micelle and nanoparticle drug delivery systems evolved due to the emergence of stimuli-responsive polymers.
Rahul S. Kalhapure, Jwala Renukuntla
semanticscholar   +1 more source

Polymerized Micelles and Their Use as Adjuvants in Immunology

Journal of Pharmaceutical Sciences, 1976
A polymerization process is described for the preparation of hydrophilic micelles containing solubilized drug molecules in a colloidal aqueous system of dissolved monomers. A hydrocarbon medium constitutes the outer phase. After secondary solubilization with the aid of selected surfactants, polymerization of micelles under different conditions takes ...
G, Birrenbach, P P, Speiser
openaire   +2 more sources

Polymerization of Rodlike Micelles

Langmuir, 1999
A new polymerizable surfactant, cetyltrimethylammonium 4-vinylbenzoate (CTVB), has been prepared and investigated. In aqueous solution, highly entangled rodlike aggregates are formed at millimolar surfactant concentrations. Free-radical polymerization of the surfactant counterions results in nearly complete conversion to a stable, nonviscous solution ...
openaire   +1 more source

Synthesis of Photolabile Fluorescent Polymeric Micelles

Journal of Nanoscience and Nanotechnology, 2014
A new amphiphilic block copolymers were synthesized with the atom transfer radical polymerization (ATRP) method. Then, the micelle structures were fabricated with a self-assembly method for application in nanocarriers and sensing. The fluorescent intensity was increased by a factor of 4 in the micelle solution due to more stacked pyrene moieties.
Teahoon, Park   +3 more
openaire   +2 more sources

Polymerized micelles with compartments

Current Opinion in Colloid & Interface Science, 2003
Multicompartment micelles with distinct hydrophobic microdomains having different properties have been realized via micellar polymers bearing hydrocarbon and fluorocarbon fragments. In aqueous solution, such polymers can self-organize into coexisting hydrocarbon and fluorocarbon microdomains that selectively solubilize different hydrophobes.
openaire   +2 more sources

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