Results 71 to 80 of about 104,249 (311)
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
Functional Modelling of Water Vapour Transmission through Surface Defects Using Surface Segmentation Analysis [PDF]
, 2015 Flexible photovoltaic films have been recently shown to have efficiencies comparable to those of solid Si based photovoltaics. Flexible PV films have significant advantages in terms of ease of manufacture by roll-to-roll (R2R) techniques and in easy ...
Blunt, Liam, Elrawemi, Mohamed
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KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer
Molecular Oncology, EarlyView.Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan +16 more
wiley +1 more source
FEBS Open Bio, EarlyView.Mouse pre‐implantation development involves a transition from totipotency to pluripotency. Integrating transcriptomics, epigenetic profiling, low‐input proteomics and functional assays, we show that eight‐cell embryos retain residual totipotency features, whereas cytoskeletal remodeling regulated by the ubiquitin‐proteasome system drives progression ...
Wanqiong Li +8 more
wiley +1 more source
PARP inhibitors induce a senescence phenotype in non‐small cell lung carcinoma cell lines
FEBS Open Bio, EarlyView.Talazoparib is the most potent inducer of senescence among different PARP1 inhibitors in human NSCLC cells. In the absence of PARP, no senescence phenotype was observed, demonstrating that PARP1 is necessary for the induction of senescence by this inhibitor.
Camille Huart +7 more
wiley +1 more source
Polyaniline membranes for use in organic solvent nanofiltration [PDF]
, 2009 Imperial Users ...
Loh, Xun Xing, Loh, Xun Xing
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Thermo-mechanical processing of sugar beet pulp. I. Twin-screw extrusion process [PDF]
, 2006 Sugar beet pulp (SBP) is the raffinate of sugar extraction. Composed of empty vegetal cells, three quarters of it consist of polysaccharides. As it is cheap and produced in great quantities SBP is a potential raw material for industrial applications ...
Jorda, Jérémy +2 more
core +2 more sources
Thermosetting polymer composites: Manufacturing and properties study
REVIEWS ON ADVANCED MATERIALS SCIENCE, 2023 Abstract In the proposed study, TiC is used in different sizes (i.e., 70–150 nm and 200–250 μm) and different ratios (e.g., 0, 10, 20, and 30 wt%) to reinforce the epoxy matrix. Micro- or nano-epoxy–TiC mixtures are poured into molds that have been prepared.
openaire +2 more sources
FEBS Open Bio, EarlyView.Matrix metalloproteinase‐9 (MMP9) drives ovarian cancer progression. Using MMP9‐null cells (M9‐KO) created from ovarian cancer cells, we found MMP9 loss did not block Epidermal Growth Factor (EGF)‐driven E‐cadherin dissolution or EMT but delayed and reduced EGF‐driven membrane protrusions. Transient MMP9 re‐expression drove membrane protrusion.
Claire Strauel +8 more
wiley +1 more source
Mechanical Properties and Biological Responses of Bioactive Glass Ceramics Processed using Indirect SLS [PDF]
, 2005 This paper will report on research which aims to generate bone replacement components by processing bioactive glass-ceramic powders using indirect selective laser sintering.
Dalgarno, K. W. +6 more
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