Results 81 to 90 of about 32,544 (317)

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

FEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane, Lea Nikolić, Lorenzo Maraio, Thomas Goiran, Nathan Karpilovsky, Stefano Sellitto, Vangelis Bouris, Jiang‐An Yin, Ronald Melki, Edward A Fon, Adriano Aguzzi, Elena De Cecco   +11 more
wiley   +1 more source

Design and Development of Concretes for Special Rehabilitation Tasks

MATEC Web of Conferences, 2018
The requirements for concrete restoration are not only aspects of retrofitting or restoration of bearing capacity but also aspects of preservation of historic structures, such as industrial monuments or civil engineering structures and buildings of the ...
Flohr Alexander, Osburg Andrea
doaj   +1 more source

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

FEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová, Grigorii Rakhalskii, Miroslav Almáši   +2 more
wiley   +1 more source

Tunnel Encapsulation Technology for Durability Improvement in Stretchable Electronics Fabrication

Micromachines, 2018
Great diversity of process technologies and materials have been developed around stretchable electronics. A subset of them, which are made up of zigzag metal foil and soft silicon polymers, show advantages of being easy to manufacture and low cost ...
Kangmin Leng, Chuanfei Guo, Kang Wu, Zhigang Wu   +3 more
doaj   +1 more source

Additive manufacturing of highly entangled polymer networks

Science
Incorporation of polymer chain entanglements within a single network can synergistically improve stiffness and toughness, yet attaining such dense entanglements through vat photopolymerization additive manufacturing [e.g., digital light processing (DLP)] remains elusive.
Abhishek P. Dhand, Matthew D. Davidson, Hannah M. Zlotnick, Thomas J. Kolibaba, Jason P. Killgore, Jason A. Burdick   +5 more
openaire   +3 more sources

Fabrication and characterisation of 3 dimensional scaffold for tissue engineering application via microstereolithography technique [PDF]

Microstereolithography is a method used for rapid prototyping of polymeric and ceramic components. This technique converts a computer-aided design (CAD) to a three dimensional (3D) model, and enables layer-per-layer fabrication curing a liquid resin ...
Talib, Marina
core  

Elaboração e caracterização de membranas de gelatina eletrofiadas e modificadas por Glutaraldeído ou nanocristais de celulose [PDF]

, 2015
Tese (doutorado) - Universidade Federal de Santa Catarina, Centro Tecnológico, Programa de Pós-Graduação em Engenharia Química, Florianópolis, 2015.A gelatina é um polímero obtido a partir do colágeno que apresenta diferentes características e ...
Niehues, Eduardo
core  

Evaluating the involvement of autolysosomes in the nuclear translocation of fluorescent proteins

FEBS Open Bio, EarlyView.
Endogenously expressed fluorescent proteins can be degraded by autophagy and transported to cell nuclei via the nuclear pore complex. But in some cell lines, for example, HeLa cells which are positive for immunoreactivity of a receptor ligand, such as UCN I, in cell nuclei, fusion of autolysosome with the nuclear envelope is involved in the nuclear ...
Keiichi Ikeda
wiley   +1 more source

Artificial Intelligence in Advanced Polymer Manufacturing

MRS Communications
Artificial intelligence (AI) is currently transforming the polymer lifecycle, from materials discovery and design to manufacturing and recycling processes. In this review, we will discuss the undergoing paradigm shift from conventional labor-intensive processes to machine learning and data driven automation, including the key machine learning models ...
Jihua Chen, Rigoberto Advincula
openaire   +1 more source

A new flow chip in combination with multiphoton microscopy as a protocol for longitudinal 3D imaging of tissue calcification under shear stress

FEBS Open Bio, EarlyView.
Miniaturized flow chip platform enabling continuous perfusion and longitudinal multiphoton 3D imaging of vascular smooth muscle cell constructs under physiological flow. Brightfield imaging guides region selection, while CellTracker Green and mRuby‐labeled fetuin‐A visualize cells and mineral deposition, respectively. Magnesium supplementation markedly
Vytautas Kučikas, Aaron D. Morgan, Ignas Čiurlionis, Christian Böhm, Stefan Jockenhövel, Willi Jahnen‐Dechent, Marc A. M. J. van Zandvoort   +6 more
wiley   +1 more source