Results 101 to 110 of about 3,624 (199)
Independent responsive behaviour and communication in hydrogel objects [PDF]
, 2017 In this work, we show the fabrication of soft hydrogel alginate-based objects, namely fibres and beads, that have an individually programmed time delay in their response to a shared environmental stimulus. We utilize the enzyme urease to programme a self-
Bon, Stefan A. F., Jaggers, Ross W.
core +1 more source
Enzymatically triggered rupture of polymersomes [PDF]
Soft Matter, 2016 Polymersomes are robust vesicles made from di-block co-polymers. We have engineered a two step enzymatic cascade to trigger the release of contents from polymersomes, in which extravesicular glucose oxidase makes hydrogen peroxide, when then penetrates the membrane and is converted by entrapped catalase to oxygen, leading to vesicle failure.
Woo-Sik, Jang +6 more
openaire +2 more sources
Tissue plasminogen activator-based clot busting: Controlled delivery approaches. [PDF]
, 2014 Cardiovascular diseases are the leading cause of death worldwide. Thrombosis, the formation of blood clot (thrombus) in the circulatory system obstructing the blood flow, is one of the main causes behind various ischemic arterial syndromes such as ...
El-Sherbiny, IM, Elkholi, IE, Yacoub, MH
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Recent advances in arsenic trioxide encapsulated nanoparticles as drug delivery agents to solid cancers [PDF]
, 2017 Since arsenic trioxide (ATO) was first approved as the front line therapy for acute promyelocytic leukemia (APL) 25 years ago, its anti-cancer properties for various malignancies have been under intense investigation.
Akhtar, Anam +4 more
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Phasentrennung von Nukleinsäuren: Mechanismen, Eigenschaften und Anwendungen
Angewandte Chemie, Volume 138, Issue 11, 9 March 2026.Jüngste Entdeckungen zeigen, dass einzelsträngige langkettige Nukleinsäuren temperaturinduziert phasentrennen und dabei mikrometergroße Kondensate bilden. Dieser Minireview fasst das aktuelle mechanistische Verständnis dieses Phänomens zusammen, beschreibt Strategien zur gezielten Kontrolle der physikalischen und chemischen Eigenschaften der Kondensate
Weixiang Chen +2 more
wiley +1 more source
Vesicle Morphogenesis in Amphiphilic Triblock Copolymer Solutions
Colloids and InterfacesCoarse-grained molecular dynamics simulations are employed to investigate the spatiotemporal evolution of vesicles (polymersomes) through the self-assembly of randomly distributed amphiphilic BAB triblock copolymers with hydrophilic A and hydrophobic B ...
Senyuan Liu +2 more
doaj +1 more source
Elucidating the Influence of Tumor Presence on the Polymersome Circulation Time in Mice
Pharmaceutics, 2019 The use of nanoparticles as tumor-targeting agents is steadily increasing, and the influence of nanoparticle characteristics such as size and stealthiness have been established for a large number of nanocarrier systems.
Robin M. de Kruijff +7 more
doaj +1 more source
Superparamagnetic iron oxide nanoparticles mediated 131I-hVEGF siRNA inhibits hepatocellular carcinoma tumor growth in nude mice [PDF]
, 2014 BACKGROUND: Hepatocellular carcinoma (HCC) is a primary liver tumor and is the most difficult human malignancy to treat. In this study, we sought to develop an integrative approach in which real-time tumor monitoring, gene therapy, and internal ...
Fei Chen +7 more
core +1 more source
Phase Separation of Nucleic Acids: Mechanisms, Properties, and Applications
Angewandte Chemie International Edition, Volume 65, Issue 11, 9 March 2026.Recent discoveries have shown that single‐stranded long‐chain nucleic acids can undergo temperature‐induced phase separation, enabling formation of micrometer‐sized condensates. This Minireview discusses the current mechanistic understanding of this phenomenon, highlights strategies for controlling the physical and chemical properties of these ...
Weixiang Chen +2 more
wiley +1 more source