Results 81 to 90 of about 3,624 (199)

Synthetic Vesicle-Based Drug Delivery Systems for Oral Disease Therapy: Current Applications and Future Directions

Journal of Functional Biomaterials
Oral diseases such as dental caries, periodontitis, and oral cancer are prevalent and present significant challenges to global public health. Although these diseases are typically treated through procedures like dental preparation and resin filling ...
Pengjie Huang, Weichang Li, Jiezhong Guan, Yibing Jia, Dan Wang, Yurun Chen, Niu Xiao, Songyue Ou, Yan Wang, Bo Yang   +9 more
doaj   +1 more source

Density-tunable conjugation of cyclic RGD ligands with polyion complex vesicles for the neovascular imaging of orthotopic glioblastomas

Science and Technology of Advanced Materials, 2015
Introduction of ligands into 100 nm scaled hollow capsules has great potential for diagnostic and therapeutic applications in drug delivery systems. Polyethylene glycol-conjugated (PEGylated) polyion complex vesicles (PICsomes) are promising hollow nano ...
Wataru Kawamura, Yutaka Miura, Daisuke Kokuryo, Kazuko Toh, Naoki Yamada, Takahiro Nomoto, Yu Matsumoto, Daiki Sueyoshi, Xueying Liu, Ichio Aoki, Mitsunobu R Kano, Nobuhiro Nishiyama, Tsuneo Saga, Akihiro Kishimura, Kazunori Kataoka   +14 more
doaj   +1 more source

One-pot RAFT and fast polymersomes assembly: a ‘beeline’ from monomers to drug-loaded nanovectors [PDF]

, 2016
Rapid and simple routes to functional polymersomes are increasingly needed to expand their clinical or industrial applications. Here we describe a novel strategy where polymersomes are prepared through an in-line process in just a few hours, starting ...
A. D. Johnstone, A. F. Breen, Ahmed, Anajafi, Battaglia, Battaglia, Blanazs, Bleul, Brinkhuis, C. Alexander, C. Grainger-Boultby, Caliceti, Capello, Chambon, Discher, Discher, Duncanson, F. Mastrotto, Fissan, G. E. Marsh, G. Mantovani, G. Sicilia, Gody, Gody, Gody, Gody, Gonzato, Guan, Hadjiantoniou, Hammer, Hoo, Huo, Kamat, Karagoz, Kim, Ladmiral, Lee, Li, Liang, Lim Soo, Liu, Liu, Lutz, Marsden, Mastrotto, Mastrotto, Meng, Messager, Moad, Moad, N. A. Russell, Nardin, Peters, Qi, S. Murdan, Sato, Schillén, Sugihara, Thiele, Tian, Tomaszewska, Vandenbergh, Wang, Wang, Warren, Wilson, Yeow, Yeow, Zhang, Zhao   +69 more
core   +2 more sources

Quantification of intracellular payload release from polymersome nanoparticles

, 2016
Polymersome nanoparticles (PMs) are attractive candidates for spatio-temporal controlled delivery of therapeutic agents. Although many studies have addressed cellular uptake of solid nanoparticles, there is very little data available on intracellular ...
Bailey, Joanne L., Cheong, Ying C., Evans, Nicholas D., Janeczek, Agnieszka A., Johnston, Alexander H., Newman, Tracey A., Oreffo, Richard O.C., Scarpa, Edoardo, Stumpf, Patrick S., Woo, Yin L.   +9 more
core   +1 more source

Haemoglobin, oxygen carriers and perioperative organ perfusion [PDF]

, 2008
Under normal conditions, only 20-30% of the delivered oxygen is metabolised. In normovolaemic anaemia, the organism reacts with increases in cardiac output and oxygen extraction.
Kocian, R, Spahn, D R
core   +1 more source

pH responsive polymersome Pickering emulsion for simple and efficient Janus polymersome fabrication [PDF]

Chem. Commun., 2014
A versatile and easy to use method is reported for the preparation of Janus polymersomes via a Pickering emulsion strategy.
Wang, Z.P., Rutjes, F.P.J.T., van Hest, J.C.M., van Hest, J.C.M.   +3 more
openaire   +3 more sources

Transmembrane Condensation in Albumin‐Loaded Giant Vesicles Induced by an Intrinsically Disordered Protein

ChemSystemsChem, Volume 8, Issue 3, May 2026.
An intrinsically disordered protein, Q20, forms transmembrane condensates with albumin‐loaded lipid and hybrid giant vesicles. Condensate insertion and membrane remodeling depend on giant vesicle size and membrane properties, inducing local lipid coupling without leakage and revealing a robust membrane‐condensate interplay.
Paula De Dios Andres, Ankush Garg, Ramy Alam, Isabella N. Westensee, Magnus Kjaergaard, Brigitte Städler   +5 more
wiley   +1 more source

Shaping polymersomes into predictable morphologies via out-of-equilibrium self-assembly

Nature Communications, 2016
Polymersomes are used in many applications, ranging from drug delivery to microfluidics, but controlling their shape is difficult. Here, Christianen and co-workers have precisely controlled polymersome shape via an out-of-equilibrium process and fully ...
R. S. M. Rikken, H. Engelkamp, R. J. M. Nolte, J. C. Maan, J. C. M. van Hest, D. A. Wilson, P. C. M. Christianen   +6 more
doaj   +1 more source

Natural channel protein inserts and functions in a completely artificial, solid-supported bilayer membrane [PDF]

, 2013
Reconstitution of membrane proteins in artificial membrane systems creates a platform for exploring their potential for pharmacological or biotechnological applications.
Fu, Wangyang, Meier, Wolfgang, Palivan, Cornelia G., Zhang, Xiaoyan   +3 more
core   +1 more source

Therapeutic Gases in Biomedicine: Updates on Nitric Oxide and Beyond

Advanced Science, Volume 13, Issue 23, 23 April 2026.
Therapeutic gases, including NO, CO, H2S, H2, CO2, O2, and Xe, play vital roles in cellular signaling and repair. This review highlights the emerging carriers and delivery systems that enable controlled, localized gas release for diagnostic and therapeutic applications.
Syed Muntazir Andrabi, Navatha Shree Sharma, Imran Ibn Gani Rather, S. M. Shatil Shahriar, Jingwei Xie   +4 more
wiley   +1 more source