Results 81 to 90 of about 2,445 (197)

Formation of non-spherical polymersomes driven by hydrophobic directional aromatic perylene interactions

Nature Communications, 2017
Polymersomes have become a powerful tool in drug delivery and synthetic biology, but their use can be restricted by a lack of versatile methods for shape control. Here the authors demonstrate access to a range of non-spherical polymersome morphologies by
Chin Ken Wong, Alexander F. Mason, Martina H. Stenzel, Pall Thordarson   +3 more
doaj   +1 more source

Polymersomes with micellar patches

Journal of Colloid and Interface Science
Hollow block copolymer particles called polymer vesicles (polymersomes) serve as versatile containers for compartmentalization in synthetic biology and drug delivery. Recently, there has been growing interest in using polymersomes as colloidal building blocks for creating higher-order clustered structures.
Chin Ken Wong, Rebecca Y. Lai, Martina H. Stenzel   +2 more
openaire   +2 more sources

Chemical and Biological Determinants of PEG‐Lipid Shedding From Therapeutic Nanoparticles

Small, Volume 22, Issue 58, 16 October 2026.
PEG‐lipids play a central role in governing lipid nanoparticle stability, targeting, and function. However, PEG‐lipids can “shed” from the nanoparticle surface in biological environments, with the extent and kinetics of shedding influenced by chemical and biological factors.
Ethan P. Cisneros, Aadya S. Wijesekera, Lisa R. Volpatti   +2 more
wiley   +1 more source

Enzymatically triggered rupture of polymersomes [PDF]

Soft Matter, 2016
Polymersomes are robust vesicles made from di-block co-polymers. We have engineered a two step enzymatic cascade to trigger the release of contents from polymersomes, in which extravesicular glucose oxidase makes hydrogen peroxide, when then penetrates the membrane and is converted by entrapped catalase to oxygen, leading to vesicle failure.
Woo-Sik, Jang, Seung Chul, Park, Ellen H, Reed, Kevin P, Dooley, Samuel F, Wheeler, Daeyeon, Lee, Daniel A, Hammer   +6 more
openaire   +2 more sources

Fluorescence recovery after photobleaching (FRAP) analysis shows that polymersome membranes are fluid.

, 2016
(a) Epifluorescence imaging of a representative PEO-PBD polymersome pre-, during and post-fluorescence bleaching. The region of the membrane that was bleached is circled. Scale bar = 10 μm.
Andrew Gomez (3155220), Walter F. Paxton (1277802), Virginia VanDelinder (1634374), Ian M. Henderson (1568662), Adrienne C. Greene (3155223), George D. Bachand (1634359)   +5 more
core   +1 more source

Nanoparticle and Membrane Responses in Plasmonic Polymeric Vesicles Under Distinct Pulsed Laser Irradiation Regimes

Small Structures, Volume 7, Issue 10, October 2026.
This investigation combines experimental characterization with numerical modeling to reveal how laser parameters such as fluence and pulse duration influence the behavior of membrane‐incorporated photoexcited gold nanoparticles. This gives rise to distinct nanoparticle modifications and membrane response pathways ranging from localized permeabilization
Regina L. Salzer, Cory J. Trout, Ajay N. Shah, Jiantao Kong, Sean M. O’Malley, Julianne C. Griepenburg   +5 more
wiley   +1 more source

Vesicle Morphogenesis in Amphiphilic Triblock Copolymer Solutions

Colloids and Interfaces
Coarse-grained molecular dynamics simulations are employed to investigate the spatiotemporal evolution of vesicles (polymersomes) through the self-assembly of randomly distributed amphiphilic BAB triblock copolymers with hydrophilic A and hydrophobic B ...
Senyuan Liu, Mohammad Sadegh Samie, Radhakrishna Sureshkumar   +2 more
doaj   +1 more source

Bacteria‐Responsive Nanostructured Drug Delivery Systems for Targeted Antimicrobial Therapy

Advanced Materials, Volume 38, Issue 51, 11 September 2026.
Bacteria‐responsive nanocarriers are designed to release antimicrobials only in the presence of infection‐specific cues. This selective activation ensures drug release precisely at the site of infection, avoiding premature or indiscriminate release, and enhancing efficacy.
Guillermo Landa, Gracia Mendoza, Silvia Irusta, Manuel Arruebo   +3 more
wiley   +1 more source

Biocompatible Functionalization of Polymersome Surfaces: A New Approach to Surface Immobilization and Cell Targeting Using Polymersomes

, 2016
Vesicles assembled from amphiphilic block copolymers represent promising nanomaterials for applications that include drug delivery and surface functionalization.
Stefan Egli (2217757), Vimalkumar Balasubramanian (1597528), Cornelia Palivan (2051548), Martin G. Nussbaumer (2217754), Mohamed Chami (367546), Nico Bruns (1300149), Wolfgang Meier (1277130)   +6 more
core   +1 more source

Self-Reporting Polysaccharide Polymersome for Doxorubicin and Cisplatin Delivery to Live Cancer Cells

, 2021
We report self-reporting fluorescent polysaccharide polymersome nanoassemblies for enzyme-responsive intracellular delivery of two clinical anticancer drugs doxorubicin (DOX) and cisplatin to study the real-time drug-releasing aspects by fluorescent ...
Mishika Virmani, Manickam Jayakannan (1443418), Manickam Jayakannan, Nilesh Umakant Deshpande, Shahidkhan Pathan, Mishika Virmani (11883099), Shahidkhan Pathan (11883102), Nilesh Umakant Deshpande (1546804)   +7 more
core   +1 more source