Results 61 to 70 of about 2,445 (197)

Stimuli-responsive polymersomes and nanoreactors [PDF]

Journal of Materials Chemistry B, 2016
Macromolecular self-assembly is attracting increasing scientific interest in polymer science.
Che, H., van Hest, J.C.M., van Hest, J.C.M.   +2 more
openaire   +3 more sources

Polyglycerol-Shelled Reduction-Sensitive Polymersome for DM1 Delivery to HER-2-Positive Breast Cancer. [PDF]

Biomacromolecules
Supramolecular delivery systems with the prolonged circulation, the potential for diverse functionalization, and few toxin-related limitations have been extensively studied.
Ma G, Braatz D, Tang P, Yang Y, Quaas E, Ludwig K, Ma N, Sun H, Zhong Z, Haag R.   +9 more
europepmc   +2 more sources

Artificial Cell Catalysts for Biotransformation: Design Principles and Process Integration

Biotechnology and Bioengineering, EarlyView.
ABSTRACT Artificial cell catalysts are emerging as programmable biocatalytic platforms for sustainable molecular conversion. By reconstituting enzymes and functional modules within synthetic compartments, they combine the selectivity of biological catalysis with the design flexibility of synthetic materials.
Iori Kobayashi, Shogo Yoshimoto, Katsutoshi Hori   +2 more
wiley   +1 more source

Synthetic Vesicle-Based Drug Delivery Systems for Oral Disease Therapy: Current Applications and Future Directions

Journal of Functional Biomaterials
Oral diseases such as dental caries, periodontitis, and oral cancer are prevalent and present significant challenges to global public health. Although these diseases are typically treated through procedures like dental preparation and resin filling ...
Pengjie Huang, Weichang Li, Jiezhong Guan, Yibing Jia, Dan Wang, Yurun Chen, Niu Xiao, Songyue Ou, Yan Wang, Bo Yang   +9 more
doaj   +1 more source

Density-tunable conjugation of cyclic RGD ligands with polyion complex vesicles for the neovascular imaging of orthotopic glioblastomas

Science and Technology of Advanced Materials, 2015
Introduction of ligands into 100 nm scaled hollow capsules has great potential for diagnostic and therapeutic applications in drug delivery systems. Polyethylene glycol-conjugated (PEGylated) polyion complex vesicles (PICsomes) are promising hollow nano ...
Wataru Kawamura, Yutaka Miura, Daisuke Kokuryo, Kazuko Toh, Naoki Yamada, Takahiro Nomoto, Yu Matsumoto, Daiki Sueyoshi, Xueying Liu, Ichio Aoki, Mitsunobu R Kano, Nobuhiro Nishiyama, Tsuneo Saga, Akihiro Kishimura, Kazunori Kataoka   +14 more
doaj   +1 more source

Polymersome-mediated cytosolic delivery of cyclic dinucleotide STING agonist enhances tumor immunotherapy

Bioactive Materials, 2022
Cyclic dinucleotides (CDNs) as stimulator of interferon genes (STING) agonists capable of inducing strong antitumor innate immune response are highly promising for tumor immunotherapy. The efficacy of these CDNs is, however, reduced greatly by their fast
Huan Zheng, Beibei Guo, Xinyun Qiu, Yifeng Xia, Yan Qu, Liang Cheng, Fenghua Meng, Zhiyuan Zhong   +7 more
doaj   +1 more source

Crystalline Poly(L‐Lactic Acid) Nanoparticles via Nonsolvent‐Induced Cascade Phase Separation

Journal of Polymer Science, EarlyView.
Water is used as the nonsolvent to induce liquid/liquid phase separation (LLPS) of poly(L‐lactic acid) (PLLA)/propylene carbonate solution and PLLA crystallization. Due to the two levels of cascade LLPS coupled with confined PLLA crystallization, three types of polymeric nanoparticles, including PLLA single crystals, Ouzo crystalsomes, and sheaf‐like ...
Niloofar Esmati, Shichen Yu, Carl T. Furner, Christopher Y. Li   +3 more
wiley   +1 more source

Development of a Polymersome Blood Ammonia Assay Coupled with a Portable Near-Infrared Fluorometer [PDF]

ACS Bio & Med Chem Au
Marie-Lynn Al-Hawat, Justine Caron, Sarah Djebbar, Simon Matoori   +3 more
doaj   +2 more sources

Mechano‐Chemical Coordination of Nanoparticle‐Based Artificial Antigen‐Presenting Cells Synergistically Tunes T Cell Activation and Expansion Phenotypes

Small, EarlyView.
Mechanically distinct nano artificial antigen‐presenting cells with independently controlled antibody density are used to reveal how physical and biochemical cues jointly regulate human T‐cell activation. Increasing stiffness and antibody density accelerates activation, enhances expansion, and promotes effector‐associated differentiation, whereas ...
Zichao Guo, Fei Hou, Yali Zhang, Zilin Ye, Yang Li, Supun Ranaweera, Yue Hui, Chun‐Xia Zhao   +7 more
wiley   +1 more source

Optical Control of Therapeutic Synthetic Cells: Controlling Biomolecule Synthesis, Activation, and Communication

Small Methods, EarlyView.
Combining synthetic cells engineering, cell‐free expression, and optical regulation may enable a new generation of programmable synthetic cell platforms. By providing spatiotemporal control over biomolecule synthesis, activation, transport, release, and communication, light offers a versatile strategy for coordinating proteins, RNAs, peptides, and ...
Gia Bao Leon Hoang, Taniya Chakraborty
wiley   +1 more source