iRGD peptide conjugation potentiates intraperitoneal tumor delivery of paclitaxel with polymersomes [PDF]
Biomaterials, 2016 Polymersomes are versatile nanoscale vesicles that can be used for cytoplasmic delivery of payloads. Recently, we demonstrated that pH-sensitive polymersomes exhibit an intrinsic selectivity towards intraperitoneal tumor lesions.
Lorena Simón-Gracia +2 more
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Co-delivery of anti-inflammatory and antioxidant agents via polymersomes for osteoarthritis therapy [PDF]
Frontiers in PharmacologyBackgroundOsteoarthritis (OA) is a chronic degenerative joint disease primarily driven by inflammation and oxidative stress. This study aimed to develop a polymersome-based co-delivery system encapsulating hydrophilic cordycepin and hydrophobic ...
Mengjie Rui +9 more
doaj +2 more sources
Characterization of Gramicidin A in Triblock and Diblock Polymersomes and Hybrid Vesicles via Continuous Wave Electron Paramagnetic Resonance Spectroscopy [PDF]
BiomimeticsStudying membrane proteins in a native environment is crucial to understanding their structural and/or functional studies. Often, widely accepted mimetic systems have limitations that prevent the study of some membrane proteins.
Emma A. Gordon +3 more
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Designing polymersomes with surface-integrated nanoparticles through hierarchical phase separation [PDF]
Nature CommunicationsPolymersomes with surface-integrated nanoparticles, in which a smaller sphere is attached to a larger capsule, are typically formed through complex processes like membrane deformation, polymerization, or membrane functionalization.
Jingxin Shao +12 more
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Polymersomes Based Versatile Nanoplatforms for Controlled Drug Delivery and Imaging [PDF]
Advanced Pharmaceutical Bulletin, 2023 Drug delivery systems made based on nanotechnology represent a novel drug carrier system that can change the face of therapeutics and diagnosis. Among all the available nanoforms polymersomes have wider applications due to their unique characteristic ...
Rohini Kotha +4 more
doaj +1 more source
Pharmaceutics, 2021 Posterior eye tissues, such as retina, are affected in many serious eye diseases, but drug delivery to these targets is challenging due to various anatomical eye barriers.
Vijayabhaskarreddy Junnuthula +8 more
doaj +1 more source
Inherently Fluorescent Peanut-Shaped Polymersomes for Active Cargo Transportation
Pharmaceutics, 2023 Nanomotors have been extensively explored for various applications in nanomedicine, especially in cargo transportation. Motile properties enable them to deliver pharmaceutical ingredients more efficiently to the targeted site. However, it still remains a
Jianhong Wang +6 more
doaj +1 more source
Polymersomes as a potential platform for cancer immunotherapy
Materials Today Advances, 2022 With the focus in the field of cancer nanomedicine shifting from direct tumor targeting to modulation of the immune system, new opportunities arise for the employment of nanocarrier systems.
J.F. Scheerstra +4 more
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Light-Triggered Polymersome-Based Anticancer Therapeutics Delivery
Nanomaterials, 2022 Polymersomes are biomimetic cell membrane-like model structures that are self-assembled stepwise from amphiphilic copolymers. These polymeric (nano)carriers have gained the scientific community’s attention due to their biocompatibility, versatility, and ...
Elisa Hernández Becerra +3 more
doaj +1 more source
Dynamic metastable polymersomes enable continuous flow manufacturing
Nature Communications, 2023 Polymersomes are polymeric analogues of liposomes with exceptional physical and chemical properties. Despite being dubbed as next-generation vesicles since their inception nearly three decades ago, polymersomes have yet to experience translation into the
Chin Ken Wong +2 more
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